Zobrazeno 1 - 10
of 281
pro vyhledávání: '"Claus Johansen"'
Autor:
Maria Danielsen, Thomas Emmanuel, Morten Muhlig Nielsen, Lise Maria Lindahl, Maria Gluud, Niels Ødum, Line Raaby, Torben Steiniche, Lars Iversen, Rikke Bech, Terkild Brink Buus, Claus Johansen
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionThe majority of patients with mycosis fungoides (MF) have an indolent disease course, but a substantial fraction (20-30%) of patients progress to advanced stages – usually with a grave prognosis. Early differentiation between indolent a
Externí odkaz:
https://doaj.org/article/032ca7a08f2441cebfb7829eb806389e
Autor:
Thomas Emmanuel, Borislav Ignatov, Trine Bertelsen, Thomas Litman, Morten Muhlig Nielsen, Mikkel Bo Brent, Toke Touborg, Anders Benjamin Rønsholdt, Annita Petersen, Mette Boye, Ida Kaaber, Daniel Sortebech, Dorte Lybæk, Torben Steiniche, Anne Bregnhøj, Liv Eidsmo, Lars Iversen, Claus Johansen
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6086 (2024)
Secukinumab and Dead Sea treatment result in clear skin for many psoriasis patients, through distinct mechanisms. However, recurrence in the same areas after treatments suggests the existence of a molecular scar. We aimed to compare the molecular and
Externí odkaz:
https://doaj.org/article/d735d84e244343d09c858131487c8d1a
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
BackgroundHeat shock protein 90 (HSP90) is an important chaperone supporting the function of many proinflammatory client proteins. Recent studies indicate HSP90 inhibition may be a novel mechanism of action for inflammatory skin diseases; however, th
Externí odkaz:
https://doaj.org/article/f467e1c9a7b047479ba2c01ba6bc2563
Publikováno v:
JEADV Clinical Practice, Vol 1, Iss 4, Pp 307-316 (2022)
Abstract Psoriasis is a chronic inflammatory skin disease, in which molecular and cellular changes retain following clinical resolution of psoriatic lesions, a form of disease memory (‘molecular scar’) that may reestablish the psoriatic inflammat
Externí odkaz:
https://doaj.org/article/5ec9ce105bc042ff8bd8c393c8f67df1
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 17014 (2023)
Hidradenitis suppurativa is a chronic inflammatory skin disease with limited treatment options. The poorly understood pathogenesis hinders the development of effective treatments; therefore, a pressing need exists to further elucidate the molecular m
Externí odkaz:
https://doaj.org/article/d0eda3c93ae8485badbe44cab5dafe90
Autor:
Hakim Ben Abdallah, Sabine Seeler, Anne Bregnhøj, Gautam Ghatnekar, Lasse S. Kristensen, Lars Iversen, Claus Johansen
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionChronic inflammatory skin diseases may have a profound negative impact on the quality of life. Current treatment options may be inadequate, offering an unsatisfactory response or side effects. Therefore, ongoing efforts exist to identify
Externí odkaz:
https://doaj.org/article/7c72aed23989487c8e622afff88ded0b
Publikováno v:
Dermatopathology, Vol 9, Iss 2, Pp 82-93 (2022)
Immunohistochemical quantification of inflammatory cells in skin biopsies is a valuable tool for diagnosing skin diseases and assessing treatment response. The quantification of individual cells in biopsies is time-consuming, tedious, and difficult.
Externí odkaz:
https://doaj.org/article/6b6de25e761743c1b62677f006f34238
Autor:
Stefania Vetrano, Gerben Bouma, Robert J. Benschop, Thomas Birngruber, Antonio Costanzo, G. R. A. M. D’Haens, Loredana Frasca, Rainer Hillenbrand, Lars Iversen, Claus Johansen, Arthur Kaser, Hans J. P. M. Koenen, Christa Noehammer, Laurent Peyrin-Biroulet, Jeroen Raes, Leonardo Ricotti, Philip Rosenstiel, Venkata P. Satagopam, Stefan Schreiber, Severine Vermeire, Andreas Wollenberg, Stephan Weidinger, Daniel Ziemek, Silvio Danese, ImmUniverse Consortium, Alessandro Armuzzi, Alessia Butera, Andrea Cafarelli, Lucia Ciglar, Ellen van den Bogaard, Elke MGJ de Jong, Ernst Dow, Marjolijn Duijvenstein, Ahmed Essaghir, Rebecca Favaro, Gionata Fiorino, Soumyabrata Ghosh, Wei Gu, Robert Häsler, Xuehui He, Roberto Lande, Judith Logmans, Christoph Magnes, Karl Nocka, Loulou Peisl, Samuel Pineda Chavez, Angela Sorriento, Klemens Vierlinger, Laurien Waaijer, Xinhui Wang, Nicolas Wisniacki, Mary Zuniga
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Immune mediated inflammatory diseases (IMIDs) are a heterogeneous group of debilitating, multifactorial and unrelated conditions featured by a dysregulated immune response leading to destructive chronic inflammation. The immune dysregulation can affe
Externí odkaz:
https://doaj.org/article/25c0b3e1103d4243ac5ad47318b6a393
Autor:
Sabine Seeler, Liviu-Ionut Moldovan, Trine Bertelsen, Henrik Hager, Lars Iversen, Claus Johansen, Jørgen Kjems, Lasse Sommer Kristensen
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0275219 (2022)
Psoriasis is a common chronic inflammatory skin disease accompanied by heterogenous clinical and histological features, including a characteristic keratinocyte hyperproliferation and dermal immunogenic profile. In addition, psoriasis is associated wi
Externí odkaz:
https://doaj.org/article/8509030fd17848ec958f7cae86d00585
Autor:
Liviu-Ionut Moldovan, Thomas Birkballe Hansen, Morten Trillingsgaard Venø, Trine Line Hauge Okholm, Thomas Levin Andersen, Henrik Hager, Lars Iversen, Jørgen Kjems, Claus Johansen, Lasse Sommer Kristensen
Publikováno v:
BMC Medical Genomics, Vol 12, Iss 1, Pp 1-17 (2019)
Abstract Background Psoriasis is a chronic inflammatory skin disease characterized by hyperproliferation and abnormal differentiation of keratinocytes. It is one of the most prevalent chronic inflammatory skin conditions in adults worldwide, with a c
Externí odkaz:
https://doaj.org/article/e128b91bc28446c18746bdc4ef495a04