Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Claus J. Schmitges"'
Publikováno v:
Nachrichten aus Chemie, Technik und Laboratorium. 45:1105-1108
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::744180a7041fd4952746eb24d6d2c6bc
https://doi.org/10.1002/nadc.199700030
https://doi.org/10.1002/nadc.199700030
Autor:
Claus J. Schmitges, Robert D. Deeprose, Gail S. Duncan, Thomas P. Zimmerman, Gertrude B. Elion, Gerald Wolberg, Pedro Cuatrecasas
Publikováno v:
Proceedings of the National Academy of Sciences. 77:5639-5643
Mouse lymphocytes incubated with micromolar concentrations of adenosine or 3-deazaadenosine, in medium supplemented with L-homocysteine, rapidly accumulated supramillimolar concentrations of S-adenosylhomocysteine (AdoHcy) or S-3-deazaadenosylhomocys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea742a6f9e8ec929d026f4b3e8e1934
https://doi.org/10.1073/pnas.77.10.5639
https://doi.org/10.1073/pnas.77.10.5639
Publikováno v:
Life Sciences. 19:1971-1979
A naturally occurring compound, 2'-deoxyadenosine-3'-monophosphate (2'-deoxy-3'-AMP), is a potent inhibitor (K i about 10 μM) of the adenylate cuclase activity of various rat tissues, toad erythrocytes, and mammalian cells in culture. This inhibitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f7ff96e551fd807a6a7d037c0e312b
https://doi.org/10.1016/0024-3205(76)90133-8
https://doi.org/10.1016/0024-3205(76)90133-8
Publikováno v:
Proceedings of the National Academy of Sciences. 75:3693-3697
The mechanism of activation of adenylate cyclase by guanylyl-5'-imidodiphosphate [Gpp(NH)p] and NaF has been investigated by studying the reconstitution of Gpp(NH)p and NaF sensitivity of an enzyme rendered insensitive to these agents by differential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d4a9cdcc5107ec4be1e1312538c9f5
https://doi.org/10.1073/pnas.75.8.3693
https://doi.org/10.1073/pnas.75.8.3693
Publikováno v:
Journal of Biological Chemistry. 254:10459-10465
Adenylate cyclase was solubilized from rat brain particulate fraction with the nonionic detergent, Nonidet P-40. Incubation of detergent-solubilized adenylate cyclase with liposomes prepared from egg yolk phosphatidylcholine results in virtually quan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c71c2784c22566b9f60e7d6c415f5db
https://doi.org/10.1016/s0021-9258(19)86731-5
https://doi.org/10.1016/s0021-9258(19)86731-5
Autor:
Eduardo G. Lapetina, Marvin I. Siegel, Kuttikkatt Chandrabose, Pedro Cuatrecasas, Claus J. Schmitges
Publikováno v:
Proceedings of the National Academy of Sciences. 75:214-217
Various vasoactive agents (e.g., thrombin and bradykinin) and serum stimulate arachidonate production and thus prostaglandin biosynthesis in cultured fibroblasts. Treatment of 3T3 cells with the anti-inflammatory steroid, dexamethasone, inhibits this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::230df684f6a806fea0eb235f99dc69c4
https://doi.org/10.1073/pnas.75.1.214
https://doi.org/10.1073/pnas.75.1.214
Publikováno v:
Life sciences. 26(17)
3T3C 2 mouse fibroblasts rendered permeable to ( α −32 P)NAD + show cholera toxin-dependent labeling of a 45,000 m.w. protein and of a doublet of polypeptides around 52,000 m.w. These same bands are ADP-ribosylated in broken cells. Membranes prepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9528893a0dc83d2079198d7e587b1a8
https://pubmed.ncbi.nlm.nih.gov/7382723
https://pubmed.ncbi.nlm.nih.gov/7382723
Publikováno v:
Membrane Receptors ISBN: 9789400958685
A central question in biology concerns how regulation of cellular processes is achieved. A major aspect of this relates to the mechanism by which extracellular factors, e.g., growth factors, neurotransmitters, and hormones, exert their effects. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c22f8cdb5c88213b86acb76b09b278dc
https://doi.org/10.1007/978-94-009-5866-1_8
https://doi.org/10.1007/978-94-009-5866-1_8
Publikováno v:
Life sciences. 28(6)
5'-Deoxy-5'-S-isobutylthioadenosine (SIBA), a synthetic analogue of S-adenosylhomocysteine, has been reported by others to inhibit a number of biological processes and these effects of SIBA have been attributed generally to inhibition of methyltransf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cda9c63292be2b382004d72d595f76f
https://pubmed.ncbi.nlm.nih.gov/6259484
https://pubmed.ncbi.nlm.nih.gov/6259484
Molecular resolution and reconstitution of the GPP (NH) P and NAF sensitive adenylate cyclase system
Publikováno v:
Life sciences. 21(12)
When a special detergent-extraction procedure is applied to rat brain particulate fractions, the latter's adenylate cyclase activity becomes virtually unresponsive to NaF or Gpp (NH)p (guanylyl-5′-imidodiphosphate) despite the fact that under these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231601b52feed19bf9c9573fdcbc111d
https://pubmed.ncbi.nlm.nih.gov/415193
https://pubmed.ncbi.nlm.nih.gov/415193