Induced hypothermia in patients with septic shock and respiratory failure (CASS):a randomised, controlled, open-label trial

Autor: Theis Skovsgaard Itenov, Maria Egede Johansen, Morten Bestle, Katrin Thormar, Lars Hein, Louise Gyldensted, Anne Lindhardt, Henrik Christensen, Stine Estrup, Henrik Planck Pedersen, Matthew Harmon, Uday Kant Soni, Silvia Perez-Protto, Nicolai Wesche, Ulrik Skram, John Asger Petersen, Thomas Mohr, Tina Waldau, Lone Musaeus Poulsen, Ditte Strange, Nicole P Juffermans, Daniel I Sessler, Else Tønnesen, Kirsten Møller, Dennis Karsten Kristensen, Alessandro Cozzi-Lepri, Jens D Lundgren, Jens-Ulrik Jensen, Jens-Ulrik Stæhr Jensen, Jens Lundgren, Susanne Illkjær, Henry Masur, Christian Torp-Pedersen, Andrew Copas, Birgit Riis Nielsen, Jesper Grarup, Jette Hansen, Kim Nielsen, Lone Valbjørn, Sanne Lauritzen, Tina Kold, Kathrine Grundahl, Rikke Hein Rasmussen, Nikolaj Wesche, Hasse Blom, Peer Eske Jensen, Tina Galle, Bente Thaarslund, Camilla Skandov, Iben Langholz, Rasmus Ehrenfried Berthelsen, Dorthe Kjær, Merete Uldbjerg, Lily Lipsius, Magaly Engsig, Rikke Helsted, Birgitte Andersen, Eigil Nygaard, Søren Strande, Aimal Khan Bangash, Peter Søe-Jensen, Hamid Tousi, Malene Tangager, Daniel Hagi-Pedersen, Rainer Karl-Heinz Gatz, Marte Kaasen Engen, Christian Åge Wamberg, Bo Westergaard, Stine Stoktoft, Rebecca Scherwin, Finn Bærentzen, Marlene Lauritzen, Frank Pott, Christina Bruun, Christian Meyhoff, Ditte Gry Strange, Dorthe Fris Palmqvist, Claus Hemmingsen, Rune Gärtner, Kai Dieter Jung, Louise La Porte, Mette Viuf, Johannes Troglauer, Silva Borovnjak, Nina Strandkjær, Claus Bretlau, Marianna Hansen, Lea Kielsgaard Zaulich, Christian Overgaard, Katja Bergenholtz, Tejs Jansen, Mette Astrup Bæk-Jensen, Monika Detlefsen, Tannie Lund Albrechtsen, Birgitte Margareta Sode, Hans Christian Boesen, Maria Thostrup, Torben Mogens Andersen, Katrine Kjelsteen, Cilia Klara Winther Kjær, Elsebeth Haunstrup, Ole Christensen, Lone Spliid, Birgitte Rasmussen, Henriette Jejlskov, Søren Borchorst, Akil Walli Raad Abdel-Wahab, Marianne Brysting, Jette Victor, Anette Stensbirk, Karen Bjerregaard, Anne Poulsen, Annette Brix Roed, Bianca Bech, Oguz Yilmaz, Sanchit Ahuja, Iman Suleiman, Rodrigo Iglesias, Olena Breum

Publikováno v: Itenov, T S, Johansen, M E, Bestle, M, Thormar, K, Hein, L, Gyldensted, L, Lindhardt, A, Christensen, H, Estrup, S, Pedersen, H P, Harmon, M, Soni, U K, Perez-Protto, S, Wesche, N, Skram, U, Petersen, J A, Mohr, T, Waldau, T, Poulsen, L M, Strange, D, Juffermans, N P, Sessler, D I, Tønnesen, E, Møller, K, Kristensen, D K, Cozzi-Lepri, A, Lundgren, J D, Jensen, J-U, Cooling and Surviving Septic Shock (CASS) Trial Collaboration & Torp-Pedersen, C 2018, ' Induced hypothermia in patients with septic shock and respiratory failure (CASS) : a randomised, controlled, open-label trial ', The Lancet. Respiratory Medicine, vol. 6, no. 3, pp. 183-192 . https://doi.org/10.1016/S2213-2600(18)30004-3
lancet. Respiratory medicine, 6(3), 183-192. Elsevier Limited
Cooling and Surviving Septic Shock (CASS) Trial Collaboration 2018, ' Induced hypothermia in patients with septic shock and respiratory failure (CASS) : a randomised, controlled, open-label trial ', The Lancet Respiratory Medicine, vol. 6, no. 3, pp. 183-192 . https://doi.org/10.1016/S2213-2600(18)30004-3
Cooling and Surviving Septic Shock (CASS) Trial Collaboration & Hägi-Pedersen, D 2018, ' Induced hypothermia in patients with septic shock and respiratory failure (CASS) : a randomised, controlled, open-label trial ', The Lancet Respiratory Medicine, vol. 6, no. 3, pp. 183-192 . https://doi.org/10.1016/S2213-2600(18)30004-3

BACKGROUND: Animal models of serious infection suggest that 24 h of induced hypothermia improves circulatory and respiratory function and reduces mortality. We tested the hypothesis that a reduction of core temperature to 32-34°C attenuates organ dy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fcb9a085ea019bd1ce343605912b4ae
https://vbn.aau.dk/da/publications/289bbe29-9efa-461c-8aac-b6c678350723

Separate Effects of 1,25-Dihydroxyvitamin D and Calcium on Renal Calbindin-D28k and Intestinal Calbindin-D9k

Autor: P. K. Nielsen, Klaus Olgaard, Claus Hemmingsen, Michael Staun

Publikováno v: Pharmacology & Toxicology. 91:111-115

The effects of normal, low and high plasma concentrations of 1,25-(OH) 2 vitamin D (1,25-(OH) 2 D) combined with normal, low and high concentrations of plasma calcium on renal calbindin-D28k and intestinal calbindin-D9k were examined in rats. We foun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e97aa6cfd002e577b6207e8cce4b9b4e
https://doi.org/10.1034/j.1600-0773.2002.910304.x

Bi-Level Positive Airway Pressure Treatment of Obstructive Sleep Apnoea Syndrome

Autor: Claus Hemmingsen, Bjørn Dreijer, Søren Bjørn Laursen, Erik Jacobsen

Publikováno v: Respiration. 65:114-119

We evaluated the effect of non-invasive nocturnal ventilation with the bi-level positive airway pressure (BiPAP) ventilator in 12 overweight patients with verified obstructive sleep apnoea syndrome (OSAS) and nocturnal hypercapnia. All patients exhib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f945d299612919447926df8a6abcf2d3
https://doi.org/10.1159/000029241

[Cyanide poisoning]

Autor: Søren, Møller, Claus, Hemmingsen

Publikováno v: Ugeskrift for laeger. 165(25)

Cyanide is a toxic compound which inhibits the cellular utilization of oxygen. A number of substances can give rise to cyanide intoxication, which in some cases may have a delayed onset. The symptoms are non-specific and reflect cellular hypoxia. Sev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8d204103a4592dac8301daabc184486e
https://pubmed.ncbi.nlm.nih.gov/12854272

Urinary calcium excretion and renal calbindin-D28k

Autor: Michael Staun, Klaus Olgaard, Kirsten Bang, Claus Hemmingsen, Karen Meibom

Publikováno v: Europe PubMed Central

The present investigation examined the possible influence of urinary calcium excretion on the concentration of renal calbindin-D28k. Thiazide diuretics stimulate calcium transport across the epithelial cells of the distal tubule, which express calbin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d90ee71326d2dce058ba1bc49dded40
https://pubmed.ncbi.nlm.nih.gov/9398030