Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Claus, Desler"'
Autor:
Helena Borland Madsen, Jon Ambæk Durhuus, Ove Andersen, Per thor Straten, Anne Rahbech, Claus Desler
Publikováno v:
npj Metabolic Health and Disease, Vol 2, Iss 1, Pp 1-8 (2024)
Abstract The COVID-19 pandemic, caused by SARS-CoV-2, has resulted in widespread morbidity and mortality, with a significant portion of the affected population experiencing long-term health complications. This review explores the mechanisms of mitoch
Externí odkaz:
https://doaj.org/article/4083a3d8cd894abaa18d46f573504756
Autor:
Sharath Anugula, Zhiquan Li, Yuan Li, Alexander Hendriksen, Peter Bjarn Christensen, Lin Wang, Jonathan M. Monk, Niels de Wind, Vilhelm A. Bohr, Claus Desler, Robert K. Naviaux, Lene Juel Rasmussen
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e17392- (2023)
Replication stress, caused by Rev1 deficiency, is associated with mitochondrial dysfunction, and metabolic stress. However, the overall metabolic alterations and possible interventions to rescue the deficits due to Rev1 loss remain unclear. Here, we
Externí odkaz:
https://doaj.org/article/c97fbe219a0b4f4aba53cc5c825abbed
Autor:
Veena Subramanian, Brian Rodemoyer, Vivek Shastri, Lene J. Rasmussen, Claus Desler, Kristina H. Schmidt
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Bloom Syndrome (BS; OMIM #210900; ORPHA #125) is a rare genetic disorder that is associated with growth deficits, compromised immune system, insulin resistance, genome instability and extraordinary predisposition to cancer. Most efforts thus
Externí odkaz:
https://doaj.org/article/5530adb9437f48af9424959207bebd7f
Autor:
Liselotte Bruun Christiansen, Tine Lovsø Dohlmann, Trine Pagh Ludvigsen, Ewa Parfieniuk, Michal Ciborowski, Lukasz Szczerbinski, Adam Kretowski, Claus Desler, Luca Tiano, Patrick Orlando, Torben Martinussen, Lisbeth Høier Olsen, Steen Larsen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Statins lower the risk of cardiovascular events but have been associated with mitochondrial functional changes in a tissue-dependent manner. We investigated tissue-specific modifications of mitochondrial function in liver, heart and skeletal
Externí odkaz:
https://doaj.org/article/464bb8e1326e4d41b93a471fef364086
Autor:
Marlies J. W. Peeters, Pia Aehnlich, Adriano Pizzella, Kasper Mølgaard, Tina Seremet, Özcan Met, Lene Juel Rasmussen, Per thor Straten, Claus Desler
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
T-cell activation upon antigen stimulation is essential for the continuation of the adaptive immune response. Impairment of mitochondrial oxidative phosphorylation is a well-known disruptor of T-cell activation. Dihydroorotate dehydrogenase (DHODH) i
Externí odkaz:
https://doaj.org/article/d07890576b8949e18e9b8caa7c3ef5cf
Autor:
José Fernández Navarro, Deborah L. Croteau, Aleksandra Jurek, Zaneta Andrusivova, Beimeng Yang, Yue Wang, Benjamin Ogedegbe, Tahira Riaz, Mari Støen, Claus Desler, Lene Juel Rasmussen, Tone Tønjum, Marie-Christine Galas, Joakim Lundeberg, Vilhelm A. Bohr
Publikováno v:
iScience, Vol 23, Iss 10, Pp 101556- (2020)
Summary: Alzheimer disease (AD) is a devastating neurological disease associated with progressive loss of mental skills and cognitive and physical functions whose etiology is not completely understood. Here, our goal was to simultaneously uncover nov
Externí odkaz:
https://doaj.org/article/8d093f5f3f6e43889e1b6be067634ef0
Autor:
Sofie H. Møller, Maiken Mellergaard, Mikkel Madsen, Amaia V. Bermejo, Stine D. Jepsen, Marie H. Hansen, Rikke I. Høgh, Blanca I. Aldana, Claus Desler, Lene Juel Rasmussen, Elahu G. Sustarsic, Zachary Gerhart-Hines, Evangelia Daskalaki, Craig E. Wheelock, Thomas K. Hiron, Da Lin, Christopher A. O’Callaghan, Hans H. Wandall, Lars Andresen, Søren Skov
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Immune surveillance of cancer cells is facilitated by the Natural Killer Group 2D (NKG2D) receptor expressed by different lymphocyte subsets. It recognizes NKG2D ligands that are rarely expressed on healthy cells, but upregulated by tumorigenesis, pr
Externí odkaz:
https://doaj.org/article/fa640fb21c2945e8bdbb88bb137d7742
Autor:
Victoria A. Bjerregaard, Bitten Schönewolf-Greulich, Lene Juel Rasmussen, Claus Desler, Zeynep Tümer
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Background: Gilles de la Tourette syndrome (GTS) is a neurodevelopmental condition characterized by motor and vocal tics. The underlying etiology remains largely unknown, and GTS is considered as a complex multifactorial disorder associated with effe
Externí odkaz:
https://doaj.org/article/615a4a1638da401a81cfa28915ec3c8c
Autor:
Per thor Straten, Claus Desler, Marco Donia, Jürgen C. Becker, Özcan Met, Lene Juel Rasmussen, Inge Marie Svane, Gitte Holmen Olofsson, Mads Hald Andersen, Hólmfridur R. Halldórsdóttir, Evelina Martinenaite, Ana Micaela Carnaz Simões, Tina Seremet, Signe K. Skadborg, Anne Rahbech, Cathrin Ritter, Arianna Draghi, Donata Dulkeviciute, Marlies J.W. Peeters
Supplementary Methods. Table S1: primer sequences. Figure S1: PROS1 and MERTK co-expression on 3-day activated CD8+ T cells. Figure S2: TAM receptors TYRO3 and AXL are nearly absent or absent on CD8+ T cells. Figure S3: Phosphatidylserine is not a li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8718ffea8ac46e33c6d349343916074b
https://doi.org/10.1158/2326-6066.22543074.v1
https://doi.org/10.1158/2326-6066.22543074.v1
Autor:
Per thor Straten, Claus Desler, Marco Donia, Jürgen C. Becker, Özcan Met, Lene Juel Rasmussen, Inge Marie Svane, Gitte Holmen Olofsson, Mads Hald Andersen, Hólmfridur R. Halldórsdóttir, Evelina Martinenaite, Ana Micaela Carnaz Simões, Tina Seremet, Signe K. Skadborg, Anne Rahbech, Cathrin Ritter, Arianna Draghi, Donata Dulkeviciute, Marlies J.W. Peeters
The TAM family of receptor tyrosine kinases (TYRO3, AXL, and MERTK) is known to be expressed on antigen-presenting cells and function as oncogenic drivers and as inhibitors of inflammatory responses. Both human and mouse CD8+ T cells are thought to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::551d6c05a67ca18e22dde038a7b856c4
https://doi.org/10.1158/2326-6066.c.6550128.v1
https://doi.org/10.1158/2326-6066.c.6550128.v1