Zobrazeno 1 - 10
of 738
pro vyhledávání: '"Claus, Christiansen"'
Autor:
Cecilie Liv Bager, Joseph P. M. Blair, Man-Hung Eric Tang, Joachim Høg Mortensen, Anne-Christine Bay-Jensen, Peder Frederiksen, Diana Leeming, Claus Christiansen, Morten Asser Karsdal
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Citrullinated vimentin has been linked to several chronic and autoimmune diseases, but how citrullinated vimentin is associated with disease prevalence and genetic variants in a clinical setting remains unknown. The aim of this study was to
Externí odkaz:
https://doaj.org/article/c4f6f264d46947fc8cdd368070733f5f
Autor:
Susanne E. Mortazavi, Malin Inghammar, Claus Christiansen, Anne-Katrine Pesola, Mikael Stenkilsson, Magnus Paulsson
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background To prevent nosocomial transmission of SARS-CoV-2, infection prevention control (IPC) measures are implemented for patients with symptoms compatible with COVID-19 until reliable test results are available. This delays admission to
Externí odkaz:
https://doaj.org/article/91ed1a7386c14a109c111d2e31ea4307
Autor:
Anne-Christine Bay-Jensen, Asger Bihlet, Inger Byrjalsen, Jeppe Ragnar Andersen, Bente Juhl Riis, Claus Christiansen, Martin Michaelis, Hans Guehring, Christoph Ladel, Morten A. Karsdal
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The heterogeneous nature of osteoarthritis (OA) and the need to subtype patients is widely accepted in the field. The biomarker CRPM, a metabolite of C-reactive protein (CRP), is released to the circulation during inflammation. Blood CRPM le
Externí odkaz:
https://doaj.org/article/f2558c7d1f10478b8c5f1554b53e37d1
Autor:
Asger Reinstrup Bihlet, Inger Byrjalsen, Jeppe Ragnar Andersen, Simone Faurholt Simonsen, Kamilla Mundbjerg, Betina Helmer, Bente Juel Riis, Morten Asser Karsdal, Claus Christiansen
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Menopause is associated with detrimental changes in turnover of bone and cartilage and a variety of symptoms with negative impact on the quality of life. Naturally occurring isoflavones from Radix Pueraria lobata, Kudzu root, may possess
Externí odkaz:
https://doaj.org/article/fe2b4aa4d4d844318a655c0fe7a44ea6
Autor:
Line Mærsk Staunstrup, Cecilie Liv Bager, Peder Frederiksen, Jørn Wulff Helge, Søren Brunak, Claus Christiansen, Morten Karsdal
Publikováno v:
EBioMedicine, Vol 68, Iss , Pp 103391- (2021)
Background: The signalling peptide endotrophin is derived through proteolytic cleavage of the carboxyl-terminal during formation of type VI collagen. It is expressed by most descendants of the mesenchymal stem cells lineage, including adipocytes and
Externí odkaz:
https://doaj.org/article/1f571eeba36a478894bf5cad6567019f
Autor:
Asger Reinstrup Bihlet, Inger Byrjalsen, Anne-Christine Bay-Jensen, Jeppe Ragnar Andersen, Claus Christiansen, Bente Juel Riis, Morten A. Karsdal
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-10 (2019)
Abstract Background Excessive cartilage degradation is a known characteristic of osteoarthritis (OA). Biochemical markers, such as uCTX-II, have been shown to be associated with disease severity, yet the tissue origin of CTX-II has been disputed. Thi
Externí odkaz:
https://doaj.org/article/b0b4a66efd5a435386b7e6a1053b1c89
Autor:
Unnur Styrkarsdottir, Olafur A. Stefansson, Kristbjorg Gunnarsdottir, Gudmar Thorleifsson, Sigrun H. Lund, Lilja Stefansdottir, Kristinn Juliusson, Arna B. Agustsdottir, Florian Zink, Gisli H. Halldorsson, Erna V. Ivarsdottir, Stefania Benonisdottir, Hakon Jonsson, Arnaldur Gylfason, Kristjan Norland, Katerina Trajanoska, Cindy G. Boer, Lorraine Southam, Jason C. S. Leung, Nelson L. S. Tang, Timothy C. Y. Kwok, Jenny S. W. Lee, Suzanne C. Ho, Inger Byrjalsen, Jacqueline R. Center, Seung Hun Lee, Jung-Min Koh, L. Stefan Lohmander, Lan T. Ho-Pham, Tuan V. Nguyen, John A. Eisman, Jean Woo, Ping-C. Leung, John Loughlin, Eleftheria Zeggini, Claus Christiansen, Fernando Rivadeneira, Joyce van Meurs, Andre G. Uitterlinden, Brynjolfur Mogensen, Helgi Jonsson, Thorvaldur Ingvarsson, Gunnar Sigurdsson, Rafn Benediktsson, Patrick Sulem, Ingileif Jonsdottir, Gisli Masson, Hilma Holm, Gudmundur L. Norddahl, Unnur Thorsteinsdottir, Daniel F. Gudbjartsson, Kari Stefansson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Size and shape of bones are important for height and body shape. Here, Styrkarsdottir et al identify 12 loci in a GWAS for bone area derived from DXA scans and show that these loci associate with other bone-related phenotypes including osteoarthritis
Externí odkaz:
https://doaj.org/article/80e678269bfd4ce6a62646dd799db50a
Autor:
Asger Reinstrup Bihlet, Inger Byrjalsen, Anne-Christine Bay-Jensen, Jeppe Ragnar Andersen, Claus Christiansen, Bente Juel Riis, Ivo Valter, Morten A. Karsdal, Marc C. Hochberg
Publikováno v:
BMC Musculoskeletal Disorders, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Pain is the principal clinical symptom of osteoarthritis (OA), and development of safe and effective analgesics for OA pain is needed. Drug development of new analgesics for OA pain is impaired by substantial change in pain in pat
Externí odkaz:
https://doaj.org/article/aaa04b30ab1b4610b042db1c2904669f
Autor:
Morten Karsdal, Estrid Høgdall, Claus Christiansen, Jesper Skov Neergaard, Katrine Dragsbæk, Diana J. Leeming, Anne-Christine Bay-Jensen, Henrik B. Hansen, Stephanie N. Kehlet, Nicholas Willumsen, Cecilie L. Bager
Supplementary Figure 1. Serum biomarker levels in relation to time to diagnosis. Biomarker levels were plotted against the elapsed time interval between blood draw and cancer diagnosis. The plots were evaluated using a Spearman test.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656334cb2077042a0a3b8a223a9cb251
https://doi.org/10.1158/1055-9965.22437562.v1
https://doi.org/10.1158/1055-9965.22437562.v1
Autor:
Morten Karsdal, Estrid Høgdall, Claus Christiansen, Jesper Skov Neergaard, Katrine Dragsbæk, Diana J. Leeming, Anne-Christine Bay-Jensen, Henrik B. Hansen, Stephanie N. Kehlet, Nicholas Willumsen, Cecilie L. Bager
Background: An altered tumor microenvironment is one of the earliest signs of cancer and an important driver of the disease. We have seen previously that biomarkers reflecting tumor microenvironment modifications, such as matrix metalloproteinase (MM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b2a9b0a03895007857f80f7361ddda3
https://doi.org/10.1158/1055-9965.c.6515938.v1
https://doi.org/10.1158/1055-9965.c.6515938.v1