Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Claudius Speer"'
Autor:
Rupert Bright, Christoph F. Mahler, Anamika Adwaney, Dhriti Dosani, Emma Morganti, Felix Friedl, Christian Nusshag, Claudius Speer, Louise Benning, Daniel Göth, Matthias Schaier, Claudia Sommerer, Markus Mieth, Arianeb Mehrabi, Martin Zeier, Christian Morath, Frank J. M. F. Dor, Florian Kälble, Damien Ashby
Publikováno v:
Transplant International, Vol 37 (2024)
As transplant programmes have evolved to allow a wider donor pool, organ acceptance decisions have become increasingly complex and lack transparency and equality. Clinical scoring tools exist but there is limited consensus on their use. From a prospe
Externí odkaz:
https://doaj.org/article/9372fe5389ea48d7b25e10326b729dd5
Autor:
Christoph F. Mahler, Felix Friedl, Christian Nusshag, Claudius Speer, Louise Benning, Daniel Göth, Matthias Schaier, Claudia Sommerer, Markus Mieth, Arianeb Mehrabi, Lutz Renders, Uwe Heemann, Markus Krautter, Vedat Schwenger, Fabian Echterdiek, Martin Zeier, Christian Morath, Florian Kälble
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe impact of deceased donor characteristics on kidney transplant outcomes is controversial. Correspondingly, the predictive performance of deceased donor scores remains moderate, and many transplant centers lack validated criteria for gr
Externí odkaz:
https://doaj.org/article/8edf63bba72a4c9ebd7ec4d076380905
Autor:
Louise Benning, Marie Bartenschlager, Heeyoung Kim, Christian Morath, Martin Zeier, Paul Schnitzler, Ralf Bartenschlager, Claudius Speer
Publikováno v:
Vaccines, Vol 12, Iss 7, p 738 (2024)
We recently showed that an adapted SARS-CoV-2 vaccine with wildtype and BA.4/BA.5 Omicron subtype epitopes induced a broad short-term immune response in hemodialysis patients. Antibodies with protective capacity were boosted significantly after a fol
Externí odkaz:
https://doaj.org/article/cd39910a4b1e49c190096ec53e541c09
Autor:
Tina Taut, Felix Kurz, Heinz-Peter Schlemmer, Clara Meinzer, Christoph Mahler, Claudius Speer, Louise Benning, Daniel Göth, Christian Nusshag, Claudia Sommerer, Matthias Schaier, Martin Zeier, Christian Morath, Florian Kälble
Publikováno v:
Ultrasound International Open, Vol 10, Iss (2024)
Purpose We analyzed which contrast-enhanced ultrasound (CEUS) parameters are associated with reduced kidney function in the early postoperative period and are prognostic for kidney function six months after transplantation.
Externí odkaz:
https://doaj.org/article/2c268b54af1645f6b4e13dbf09cc52ba
Autor:
Marvin Reineke, Christian Morath, Claudius Speer, Markus Rudek, Christian Bundschuh, Julian A.F. Klein, Christoph F. Mahler, Florian Kälble, Christian Nusshag, Jörg Beimler, Martin Zeier, Ralf Bartenschlager, Paul Schnitzler, Louise Benning
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Following kidney transplantation, lifelong immunosuppressive therapy is essential to prevent graft rejection. On the downside, immunosuppression increases the risk of severe infections, a major cause of death among kidney transplant recipients (KTRs)
Externí odkaz:
https://doaj.org/article/b7c9265149374386b4ed873db12357b9
Autor:
Louise Benning, Christian Morath, Annette Fink, Markus Rudek, Claudius Speer, Florian Kälble, Christian Nusshag, Jörg Beimler, Constantin Schwab, Rüdiger Waldherr, Martin Zeier, Caner Süsal, Thuong Hien Tran
Publikováno v:
Transplant International, Vol 36 (2023)
Donor-derived cell-free DNA (dd-cfDNA) identifies allograft injury and discriminates active rejection from no rejection. In this prospective study, 106 kidney transplant recipients with 108 clinically indicated biopsies were enrolled at Heidelberg Un
Externí odkaz:
https://doaj.org/article/dd27de4fe00d46a19c12bf2a47c50f5f
Autor:
Matthias Schaier, Christian Morath, Lei Wang, Christian Kleist, Gerhard Opelz, Thuong Hien Tran, Sabine Scherer, Lien Pham, Naruemol Ekpoom, Caner Süsal, Gerald Ponath, Florian Kälble, Claudius Speer, Louise Benning, Christian Nusshag, Christoph F. Mahler, Luiza Pego da Silva, Claudia Sommerer, Angela Hückelhoven-Krauss, David Czock, Arianeb Mehrabi, Constantin Schwab, Rüdiger Waldherr, Paul Schnitzler, Uta Merle, Vedat Schwenger, Markus Krautter, Stephan Kemmner, Michael Fischereder, Manfred Stangl, Ingeborg A. Hauser, Anna-Isabelle Kälsch, Bernhard K. Krämer, Georg A. Böhmig, Carsten Müller-Tidow, Jochen Reiser, Martin Zeier, Michael Schmitt, Peter Terness, Anita Schmitt, Volker Daniel
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe administration of modified immune cells (MIC) before kidney transplantation led to specific immunosuppression against the allogeneic donor and a significant increase in regulatory B lymphocytes. We wondered how this approach affected th
Externí odkaz:
https://doaj.org/article/e8a3a583d0ee42d7b2d399e91afea0aa
Autor:
Matthias Reinscheid, Hendrik Luxenburger, Vivien Karl, Anne Graeser, Sebastian Giese, Kevin Ciminski, David B. Reeg, Valerie Oberhardt, Natascha Roehlen, Julia Lang-Meli, Kathrin Heim, Nina Gross, Christina Baum, Siegbert Rieg, Claudius Speer, Florian Emmerich, Susanne Breisinger, Daniel Steinmann, Bertram Bengsch, Tobias Boettler, Georg Kochs, Martin Schwemmle, Robert Thimme, Christoph Neumann-Haefelin, Maike Hofmann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Vaccines induce beneficial immunity for COVID-19, but immune waning prompts boosting vaccination. Here, the authors show that a third, boosting dose of COVID-19 mRNA vaccine induces transient CD8 + T effector cell response while conserving the CD8 me
Externí odkaz:
https://doaj.org/article/fca8aca08c224586bb686b0fe9b5ffd3
Autor:
Christian Nusshag, Changli Wei, Eunsil Hahm, Salim S. Hayek, Jing Li, Beata Samelko, Christoph Rupp, Roman Szudarek, Claudius Speer, Florian Kälble, Matthias Schaier, Florian Uhle, Felix C.F. Schmitt, Mascha O. Fiedler, Ellen Krautkrämer, Yanxia Cao, Ricardo Rodriguez, Uta Merle, Jesper Eugen-Olsen, Martin Zeier, Markus A. Weigand, Christian Morath, Thorsten Brenner, Jochen Reiser
Publikováno v:
JCI Insight, Vol 8, Iss 7 (2023)
Acute kidney injury (AKI) secondary to sepsis results in poor outcomes and conventional kidney function indicators lack diagnostic value. Soluble urokinase plasminogen activator receptor (suPAR) is an innate immune–derived molecule implicated in in
Externí odkaz:
https://doaj.org/article/4d103726f05d4f84ae5ff657e01e292f
Autor:
Lei Wang, Arianeb Mehrabi, Maria-Luisa Schubert, Anita Schmitt, Brigitte Neuber, Alexander Kunz, Angela Hückelhoven-Krauss, Carsten Müller-Tidow, Michael Schmitt, Christian Morath, Martin Zeier, Constantin Schwab, Anja Sander, Sabine Scherer, Claudius Speer, Christian Kleist, Claudia Sommerer, Florian Kälble, Christian Nusshag, Matthias Schaier, Louise Benning, Vedat Schwenger, Caner Süsal, Gerhard Opelz, T. Hien Tran, Stephan Kemmner, Michael Fischereder, Manfred Stangl, Ingeborg A. Hauser, Christian Bischofs, Sandra Sauer, Rüdiger Waldherr, Christopher Büsch, David Czock, Georg A Böhmig, Jochen Reiser, Axel Roers, Peter Terness, Volker Daniel
Publikováno v:
BMJ Open, Vol 12, Iss 11 (2022)
Introduction Donor-derived modified immune cells (MIC) induced long-term specific immunosuppression against the allogeneic donor in preclinical models of transplantation. In a phase I clinical trial (TOL-1 Study), MIC treatment resulted in a cellular
Externí odkaz:
https://doaj.org/article/6362680b60bd43139a9d0cb0059a65b3