Výsledky vyhledávání - "Claudius Gottschalk"

Akademický článek

Immunosuppressive therapy influences the accelerated age-dependent T-helper cell differentiation in systemic lupus erythematosus remission patients

Autor: Matthias Schaier, Claudius Gottschalk, Lorenz Uhlmann, Claudius Speer, Florian Kälble, Volker Eckstein, Carsten Müller-Tidow, Stefan Meuer, Karsten Mahnke, Hanns-Martin Lorenz, Martin Zeier, Andrea Steinborn

Publikováno v: Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-17 (2018)

Abstract Background CD4+ T cells are of great importance in the pathogenesis of systemic lupus erythematosus (SLE), as an imbalance between CD4+ regulatory T cells (Tregs) and CD4+ responder T cells (Tresps) causes flares of active disease in SLE pat

Externí odkaz: https://doaj.org/article/ac2b83be5c3b4ba180c6c858fbe4955c

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Akademický článek

The Abbott PanBio WHO emergency use listed, rapid, antigen-detecting point-of-care diagnostic test for SARS-CoV-2-Evaluation of the accuracy and ease-of-use.

Publikováno v: PLoS ONE, Vol 16, Iss 5, p e0247918 (2021)

ObjectivesDiagnostics are essential for controlling the pandemic. Identifying a reliable and fast diagnostic device is needed for effective testing. We assessed performance and ease-of-use of the Abbott PanBio antigen-detecting rapid diagnostic test

Externí odkaz: https://doaj.org/article/17c0889f27b042c09c9b2af49f36aedd

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Akademický článek

Can we predict the severe course of COVID-19 - a systematic review and meta-analysis of indicators of clinical outcome?

Autor: Stephan Katzenschlager, Alexandra J Zimmer, Claudius Gottschalk, Jürgen Grafeneder, Stephani Schmitz, Sara Kraker, Marlene Ganslmeier, Amelie Muth, Alexander Seitel, Lena Maier-Hein, Andrea Benedetti, Jan Larmann, Markus A Weigand, Sean McGrath, Claudia M Denkinger

Publikováno v: PLoS ONE, Vol 16, Iss 7, p e0255154 (2021)

BackgroundCOVID-19 has been reported in over 40million people globally with variable clinical outcomes. In this systematic review and meta-analysis, we assessed demographic, laboratory and clinical indicators as predictors for severe courses of COVID

Externí odkaz: https://doaj.org/article/d9f9f32e78b04c228da67af04b5136d6

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Akademický článek

Prediction of local COVID-19 spread in Heidelberg [version 1; peer review: 1 approved, 2 approved with reservations]

Autor: Lisa Koeppel, Claudius Gottschalk, Andreas Welker, Britta Knorr, Claudia M. Denkinger

Publikováno v: F1000Research, Vol 9 (2020)

Since the first identified case of COVID-19 in Wuhan, China, the disease has developed into a pandemic, imposing a major challenge for health authorities and hospitals worldwide. Mathematical transmission models can help hospitals to anticipate and p

Externí odkaz: https://doaj.org/article/860d7c5e835d41b1830d1111a18cb940

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The onset of active disease in systemic lupus erythematosus patients is characterised by excessive regulatory CD4+-T-cell differentiation

Autor: Matthias, Schaier, Claudius, Gottschalk, Florian, Kälble, Lorenz, Uhlmann, Volker, Eckstein, Carsten, Müller-Tidow, Stefan, Meuer, Karsten, Mahnke, Hanns-Martin, Lorenz, Martin, Zeier, Andrea, Steinborn

Publikováno v: Clinical and Experimental Rheumatology. 39:279-288

An imbalance between CD4+-regulatory T-cells (Tregs) and CD4+-responder T-cells (Tresps) correlates with active disease flares in systemic lupus erythematosus (SLE) patients. Both cell subsets consist of highly proliferating Tregs/Tresps expressing i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7c5af2e3ae104637e63323c0673061
https://doi.org/10.55563/clinexprheumatol/cg29xj

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Evaluation of the accuracy and ease-of-use of Abbott PanBio - A WHO emergency use listed, rapid, antigen-detecting point-of-care diagnostic test forSARS-CoV-2

BackgroundDiagnostics are essential for controlling the pandemic. Identifying a reliable and fast diagnostic is needed to support testing. We assessed performance and ease-of-use of the Abbott PanBio antigen-detecting rapid diagnostic test (Ag-RDT).M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39ffe829917b8019e2e4380ebbec0292
https://doi.org/10.1101/2020.11.27.20239699

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Evaluation of the accuracy, ease of use and limit of detection of novel, rapid, antigen-detecting point-of-care diagnostics for SARS-CoV-2

BackgroundReliable point-of-care (POC) diagnostics not requiring laboratory infrastructure could be a game changer in the COVID-19 pandemic, particularly in the Global South. We assessed performance, limit of detection and ease-of-use of three antige

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0c899b65955f1a33f9761786b1f2b8f
https://doi.org/10.1101/2020.10.01.20203836

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P0413THE ICOS+ TREG/ICOS+ TRESP BALANCE HAS A DECISIVE ROLE REGARDING THE PRESERVATION OF THE REMISSION PHASE IN SLE PATIENTS

Autor: Claudius Gottschalk, Florian Kälble, Andrea Steinborn, Matthias Schaier, Martin Zeier

Publikováno v: Nephrology Dialysis Transplantation. 35

Background and Aims An imbalance between CD4+-regulatory T-cells (Tregs) and CD4+-responder T-cells (Tresps) correlates with active disease flares in Systemic Lupus Erythematosus (SLE) patients. Both cell subsets consist of highly proliferative induc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4499bf13424a5d1e1ba90b6e205859b6
https://doi.org/10.1093/ndt/gfaa142.p0413

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