Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Claudiu Supuran"'
Autor:
Alessia Costa, Barbara Rani, Fiorella Casamenti, Patrizio Blandina, Claudiu Supuran, Maria Passani, Gustavo Provensi
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S477-S478 (2023)
Externí odkaz:
https://doaj.org/article/36f33faf3e124722a0a76abc62f9e7e5
Autor:
Elisabetta Barresi, Rahul Ravichandran, Lorenzo Germelli, Andrea Angeli, Emma Baglini, Silvia Salerno, Anna Maria Marini, Barbara Costa, Eleonora Da Pozzo, Claudia Martini, Federico Da Settimo, Claudiu Supuran, Sandro Cosconati, Sabrina Taliani
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1783-1797 (2021)
Carbonic Anhydrase Activators (CAAs) could represent a novel approach for the treatment of Alzheimer’s disease, ageing, and other conditions that require remedial achievement of spatial learning and memory therapy. Within a research project aimed a
Externí odkaz:
https://doaj.org/article/61803acb569c43b59486f5dce895777a
Autor:
Claudiu Supuran
Publikováno v:
Future Medicinal Chemistry. 15:5-7
Autor:
Claudiu Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 37:2478-2488
The mitochondrial isoforms VA/VB of metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1) are involved in metabolic processes, such as
Carbonic anhydrases (CAs) are a metalloenzyme family that have important roles in cellular processes including pH homeostasis and have been implicated in multiple pathological conditions.1 Small molecule inhibitors have been developed to target carbo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aea2c2290f120f1513140bff7c74db56
https://doi.org/10.26434/chemrxiv-2023-r1cs3
https://doi.org/10.26434/chemrxiv-2023-r1cs3
Autor:
Bader Huwaimel, Sravan Jonnalagadda, Shirisha Jonnalagadda, Shikha Kumari, Alessio Nocentinic, Claudiu Supuran, Trippier Paul
Inhibition of specific carbonic anhydrase (CA) enzymes is a validated strategy for the development of agents to target cancer. The CA isoforms IX and XII are overexpressed in various human solid tumors wherein they play a critical role in regulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c42b1c4495703dd386680082f9e387cf
https://doi.org/10.26434/chemrxiv-2023-7l7d0
https://doi.org/10.26434/chemrxiv-2023-7l7d0
Autor:
Andrea Angeli, Claudiu Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 38
Autor:
Claudiu Supuran, Mattia Mori
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 672-679 (2022)
Acipimox, a nicotinic acid derivative in clinical use for the treatment of hyperlipidaemia, incorporates a free carboxylic acid and an N-oxide moiety, functionalities known to interact with the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1) and in
Autor:
Katarzyna Jakimiuk, Didem Sohretoglu, SUAT SARI, Robert Milewski, Claudiu Supuran, Michal Tomczyk
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 427-436 (2022)
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Flavonoids are widely distributed in plants and constitute the most common polyphenolic phytoconstituents in the human diet. In this study, the in vitro inhibitory activity of 44 different flavonoids (1–44) against mushroom tyrosinase was studied,
Autor:
Claudiu Supuran
Publikováno v:
Expert Opinion on Investigational Drugs. 30:1197-1208
Hypoxic tumors, unlike normal tissues, overexpress proteins involved in oxygen sensing, metabolism, pH regulation, angiogenesis, immunological response, and other survival mechanisms, which are under investigation as antitumor drug targets.Carbonic a