Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Claudiu M. Nelersa"'
Autor:
Steven G. Kernie, Claudiu M. Nelersa, Jose Mier, Tzong-Shiue Yu, Daniel J. Liebl, Kirsty J. Dixon, Michelle H. Theus, Lissette G. Travieso
Publikováno v:
Journal of Neurotrauma. 32:753-764
Although a myriad of pathological responses contribute to traumatic brain injury (TBI), cerebral dysfunction has been closely linked to cell death mechanisms. A number of therapeutic strategies have been studied in an attempt to minimize or ameliorat
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
NanoRNAs are RNA fragments 2 to 5 nucleotides in length that are generated as byproducts of RNA degradation and abortive transcription initiation. Cells have specialized enzymes to degrade nanoRNAs, such as the DHH phosphoesterase family member NanoR
Autor:
Stephanie J. Glass, Jerome Ricard, Erik Runko, Vance Lemmon, John L. Bixby, Yan Shi, Henry Barreras, Claudiu M. Nelersa, Daniel J. Liebl
Publikováno v:
SLAS Discovery. 17:785-795
Small-molecule compounds (SMCs) can provide an inexpensive and selective approach to modifying biological responses. High-content analysis (HCA) of SMC libraries can help identify candidate molecules that inhibit or activate cellular responses. In pa
Publikováno v:
IUBMB Life (International Union of Biochemistry and Molecular Biology: Life). 56:257-265
Ephrins and Eph receptors play important roles in the development of the central nervous system and peripheral tissues by orchestrating cellular movements, resulting in events such as axonal growth cone guidance, tissue segmentation, and angiogenic r
Publikováno v:
Acta crystallographica. Section F, Structural biology and crystallization communications. 67(Pt 10)
The final step in RNA degradation is the hydrolysis of RNA fragments five nucleotides or less in length (nanoRNA) to mononucleotides. In Escherichia coli this step is carried out by oligoribonuclease (Orn), a DEDD-family exoribonuclease that is conse
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 70:C212-C212
NanoRNA are RNA molecules 5 nt or less that are generated during several fundamental biological processes, including abortive transcription and RNA turnover. NanoRNA may play a role in the priming of transcription initiation. Degradation of nanoRNA i
Publikováno v:
Journal of the Neurological Sciences. 333:e702