Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Claudiu A Giurumescu"'
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 4, p e1000354 (2009)
During development, signaling networks control the formation of multicellular patterns. To what extent quantitative fluctuations in these complex networks may affect multicellular phenotype remains unclear. Here, we describe a computational approach
Externí odkaz:
https://doaj.org/article/17bfd3c18be946d98e8a694dfadc5952
Publikováno v:
Molecular Physics. 102:281-288
We have used Car–Parrinello constrained molecular dynamics to study the coupling of two molecules of methanol in the zeolite chabazite to form ethanol and water. We have chosen to study this reaction because it represents the formation of the first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e496e8215b0d18e8aeb17618f3cc795e
https://doi.org/10.1080/00268970410001703903
https://doi.org/10.1080/00268970410001703903
Publikováno v:
Genetics, vol 195, iss 3
Eph receptors and their ephrin ligands are key conserved regulators of axon guidance and can function in a variety of signaling modes. Here we analyze the genetic and cellular requirements for Eph signaling in a Caenorhabditis elegans axon guidance c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be68efab318d8225375700739ad52972
https://escholarship.org/uc/item/4b51z2w7
https://escholarship.org/uc/item/4b51z2w7
Quantitative semi-automated analysis of morphogenesis with single-cell resolution in complex embryos
Autor:
Andrew D. Chisholm, Joshua Bloomekatz, Sukryool Kang, Claudiu A. Giurumescu, Pamela C. Cosman, Deborah Yelon, Thomas A. Planchon, Eric Betzig
Publikováno v:
Giurumescu, C. A; Kang, S.; Planchon, T. A; Betzig, E.; Bloomekatz, J.; Yelon, D.; et al.(2012). Quantitative semi-automated analysis of morphogenesis with single-cell resolution in complex embryos. Development, 139(22), 4271-4279. doi: 10.1242/dev.086256. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/9767g76n
A quantitative understanding of tissue morphogenesis requires description of the movements of individual cells in space and over time. In transparent embryos, such as C. elegans, fluorescently labeled nuclei can be imaged in three-dimensional time-la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7288bcd0d8c69b478f4f937b3e46c5aa
http://www.escholarship.org/uc/item/9767g76n
http://www.escholarship.org/uc/item/9767g76n
Publikováno v:
SSIAI
We present a method for tracking nuclei of C. elegans cells in three dimensional time lapse (4D) data during embryogenesis. It is based on spherical model fitting with multiple target tracking. The algorithm tracks nuclei in a local search space, det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6941264da66476d74befe2c50aef65b4
https://doi.org/10.1109/ssiai.2012.6202442
https://doi.org/10.1109/ssiai.2012.6202442
Caenorhabditis elegans is uniquely suited to the analysis of cell lineage patterns. C. elegans has a small number of somatic cells whose position and morphology are almost invariant from animal to animal. Because C. elegans is virtually transparent,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fffd3f493db628067459559479935a69
https://doi.org/10.1016/b978-0-12-544172-8.00012-8
https://doi.org/10.1016/b978-0-12-544172-8.00012-8
Autor:
Andrew D. Chisholm, Claudiu A. Giurumescu, Ryann E. Swale, Alexandr Goncharov, Yishi Jin, Jennifer R. Gotenstein, Zilu Wu, Tetsuko Fukuda
Peroxidasins form a highly conserved family of extracellular peroxidases of unknown cellular function. We identified the C. elegans peroxidasin PXN-2 in screens for mutants defective in embryonic morphogenesis. We find that PXN-2 is essential for spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848379094bbb6b962b04e506b349a406
https://europepmc.org/articles/PMC2964093/
https://europepmc.org/articles/PMC2964093/
Publisher Summary This chapter appraises specification cues and the downstream context-dependent response that propels the development of multicellular organisms. Specific molecular networks and developmental systems have been discussed to provide il
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29af086ecc675755ab763386c9f7c4c3
https://doi.org/10.1016/b978-0-12-372550-9.00014-6
https://doi.org/10.1016/b978-0-12-372550-9.00014-6
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 4, p e1000354 (2009)
PLoS Computational Biology
PLoS Computational Biology
During development, signaling networks control the formation of multicellular patterns. To what extent quantitative fluctuations in these complex networks may affect multicellular phenotype remains unclear. Here, we describe a computational approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8327d5b3f5fc15b3c24e6e90cd21952c
https://resolver.caltech.edu/CaltechAUTHORS:20090820-142952457
https://resolver.caltech.edu/CaltechAUTHORS:20090820-142952457
Publikováno v:
Biotechnology progress. 24(1)
Developing design strategies for tissue engineering and regenerative medicine is limited by our nascent understanding of how cell populations "self-organize" into multicellular structures on synthetic scaffolds. Mechanistic insights can be gleaned fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9f137b436a34c267b3a6dfcb1246b2f
https://pubmed.ncbi.nlm.nih.gov/17894468
https://pubmed.ncbi.nlm.nih.gov/17894468