Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Claudio Vieira Da Silva"'
Autor:
Luana Carvalho Luz, Mayara Ribeiro, Samuel Cota Teixeira, Guilherme de Souza, Marina Paschoalino, Daniel Pereira Sousa, Alessandra Monteiro Rosini, Natalia Carine Lima dos Santos, Rafael Martins de Oliveira, Joed Pires de Lima Júnior, Izadora Santos Damasceno, Marcos Paulo Oliveira Almeida, Matheus Carvalho Barbosa, Celene Maria de Oliveira Simões Alves, Claudio Vieira da Silva, Bellisa Freitas Barbosa, Eloisa Amália Vieira Ferro
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Galectin-3 (Gal-3) is a β-galactoside-binding lectin expressed in cells of the placental microenvironment. This lectin is involved in various biological processes, such as modulation of the immune system and control of parasitic illness. Toxoplasma
Externí odkaz:
https://doaj.org/article/3643928c0d03481497a9b2b916839c55
Autor:
Anna Clara Azevedo Silveira, Nelsa Paula Inácio Uombe, Teresiama Velikkakam, Bruna Cristina Borges, Thaise Lara Teixeira, Vitelhe Ferreira de Almeida, Jhoan David Aguillon Torres, Cecília Luiza Pereira, Guilherme de Souza, Samuel Cota Teixeira, João Paulo Silva Servato, Marcelo José Barbosa Silva, Tiago Wilson Patriarca Mineo, Rosineide Marques Ribas, Renato Arruda Mortara, José Franco da Silveira, Claudio Vieira da Silva
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
P21 is a protein secreted by all forms of Trypanosoma cruzi (T. cruzi) with recognized biological activities determined in studies using the recombinant form of the protein. In our recent study, we found that the ablation of P21 gene decreased Y stra
Externí odkaz:
https://doaj.org/article/c5f3bfac25a244279fe2d50b9dff0b31
Autor:
Guilherme de Souza, Samuel Cota Teixeira, Aryani Felixa Fajardo Martínez, Rafaela José Silva, Luana Carvalho Luz, Joed Pires de Lima Júnior, Alessandra Monteiro Rosini, Natália Carine Lima dos Santos, Rafael Martins de Oliveira, Marina Paschoalino, Matheus Carvalho Barbosa, Rosiane Nascimento Alves, Angelica Oliveira Gomes, Claudio Vieira da Silva, Eloisa Amália Vieira Ferro, Bellisa Freitas Barbosa
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionToxoplasma gondii is the etiologic agent of toxoplasmosis, a disease that affects about one-third of the human population. Most infected individuals are asymptomatic, but severe cases can occur such as in congenital transmission, which ca
Externí odkaz:
https://doaj.org/article/a7ce5a03064b4a9685daf03c88697223
Autor:
Guilherme de Souza, Rafaela José Silva, Iliana Claudia Balga Milián, Alessandra Monteiro Rosini, Thádia Evelyn de Araújo, Samuel Cota Teixeira, Mário Cézar Oliveira, Priscila Silva Franco, Claudio Vieira da Silva, José Roberto Mineo, Neide Maria Silva, Eloisa Amália Vieira Ferro, Bellisa Freitas Barbosa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)
Abstract Congenital toxoplasmosis is represented by the transplacental passage of Toxoplasma gondii from the mother to the fetus. Our studies demonstrated that T. gondii developed mechanisms to evade of the host immune response, such as cyclooxygenas
Externí odkaz:
https://doaj.org/article/82b945ba401f4713b702502e03124623
Autor:
Thaise Lara Teixeira, Miguel Angel Chiurillo, Noelia Lander, Cassiano Costa Rodrigues, Thiago Souza Onofre, Éden Ramalho Ferreira, Camila Miyagui Yonamine, Júlia de Gouveia Santos, Renato Arruda Mortara, Claudio Vieira da Silva, José Franco da Silveira
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
P21 is an immunomodulatory protein expressed throughout the life cycle of Trypanosoma cruzi, the etiologic agent of Chagas disease. In vitro and in vivo studies have shown that P21 plays an important role in the invasion of mammalian host cells and e
Externí odkaz:
https://doaj.org/article/5b2466fd38424206849d38a7812c6afa
Autor:
Bruna Cristina Borges, Isadora Akemi Uehara, Marlus Alves dos Santos, Flávia Alves Martins, Fernanda Carvalho de Souza, Álvaro Ferreira Junior, Felipe Andrés Cordero da Luz, Mylla Spirandelli da Costa, Ana Flávia Oliveira Notário, Daiana Silva Lopes, Samuel Cota Teixeira, Thaise Lara Teixeira, Patrícia de Castilhos, Claudio Vieira da Silva, Marcelo José Barbosa Silva
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Trypanosoma cruzi P21 is a protein secreted by the parasite that plays biological roles directly involved in the progression of Chagas disease. The recombinant protein (rP21) demonstrates biological properties, such as binding to CXCR4 receptors in m
Externí odkaz:
https://doaj.org/article/816378c827184c298626cd08e440cdb9
Autor:
Flávia Alves Martins, Marlus Alves dos Santos, Júlia de Gouveia Santos, Aline Alves da Silva, Bruna Cristina Borges, Mylla Spirandelli da Costa, Paula Cristina Brígido Tavares, Samuel Cota Teixeira, Rebecca Tavares e Silva Brígido, Thaise Lara Teixeira, Cassiano Costa Rodrigues, Nadjania Saraiva de Lira Silva, Rayane Cristina de Oliveira, Laura Caroline de Faria, Marcela Rezende Lemes, Renata Graciele Zanon, Tatiana Carla Tomiosso, Juliana Reis Machado, Marcos Vinicius da Silva, Carlo José Freire Oliveira, Claudio Vieira da Silva
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Trypanosoma cruzi P21 protein (P21) is a putative secreted and immunomodulatory molecule with potent bioactive properties such as induction of phagocytosis and actin cytoskeleton polymerization. Despite the bioactive properties described so far, the
Externí odkaz:
https://doaj.org/article/afa149cf218941519a88ce1ba6e82709
Autor:
Cecilia Pérez Brandán, Andrea C Mesias, Leonardo Acuña, Thaise Lara Teixeira, Claudio Vieira da Silva
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 114, Iss 0 (2019)
BACKGROUND TcP21 is a ubiquitous secreted protein of Trypanosoma cruzi and its recombinant form (rP21) promotes parasite cell invasion and acts as a phagocytosis inducer by activating actin polymerisation in the host cell. OBJECTIVE Our goal was to e
Externí odkaz:
https://doaj.org/article/f73a97eb6bf24d60992aadac0c580162
Publikováno v:
Parasites & Vectors, Vol 8, Iss 1, Pp 1-4 (2015)
Abstract Background Invasion of host cells by Trypanosoma cruzi extracellular amastigotes is host actin polymerization-dependent. However, the role of proteins related to actin dynamics during invasion by amastigotes remains to be investigated. Here
Externí odkaz:
https://doaj.org/article/256709ed211a455f8e4219b509475350
Autor:
Mylla Spirandelli da Costa, Bruna Cristina Borges, Isabella Teixeira Marques, Rayane Cristina de Oliveira, Thaise Lara Teixeira, Julia de Gouveia Santos, Claudio Vieira da Silva
Publikováno v:
Chembiochem : a European journal of chemical biology. 23(18)
Pentachloropseudilin (PClP) is a reversible and allosteric inhibitor of type 1 myosin. Here, we addressed the impact of PClP treatment of Trypanosoma cruzi and mammalian host cell on the parasite migration, cell adhesion and invasion. We observed tha