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pro vyhledávání: '"Claudio Vallotto"'
Publikováno v:
Physical Chemistry Chemical Physics. 22:28173-28182
Spin hyperpolarization can dramatically increase signal intensities in magnetic resonance experiments, providing either improved bulk sensitivity or additional spectroscopic detail through selective enhancements. While typical hyperpolarization appro
Autor:
Christopher J. Wedge, Claudio Vallotto, Ruth Edge, Helen E. Williams, Damien Martin Murphy, Mark E. Newton, Zoë J. Ayres
Publikováno v:
Vallotto, C, Williams, H E, Murphy, D M, Ayres, Z J, Edge, R, Newton, M E & Wedge, C J 2017, ' An Electron Paramagnetic Resonance (EPR) spectroscopy study on the γ-irradiation sterilization of the pharmaceutical excipient L-histidine : Regeneration of the radicals in solution ', International Journal of Pharmaceutics, vol. 533, no. 1, pp. 315-319 . https://doi.org/10.1016/j.ijpharm.2017.09.068
The effects of γ-radiation sterilization on the parenteral excipient L-histidine were analysed by means of EPR spectroscopy. The irradiation process was found to induce the formation of a deamination radical which was persistent in the solid state.
Autor:
Lionel Chiron, Marc-André Delsuc, Alice M. Lynch, Mark P. Barrow, Federico Floris, Claudio Vallotto, Peter B. O’Connor
Publikováno v:
Analytical Chemistry. 89:9892-9899
Two-dimensional Fourier transform ion cyclotron resonance mass spectrometry (2D FTICR MS or 2D MS) allows direct correlation between precursor and fragment ions without isolation prior to fragmentation. The method has been optimized for the analysis
Autor:
Evyenia Shaili, Christopher J. Wedge, Mark E. Newton, Peter J. Sadler, Huayun Shi, Jennifer S. Butler, Claudio Vallotto
Publikováno v:
Chemical Communications (Cambridge, England)
l-Tryptophan (Trp), melatonin (MLT) and the Trp-peptide pentagastrin quenched the formation of azidyl radicals generated on irradiation of the anticancer complex trans,trans,trans-[Pt(pyridine)2(N3)2(OH)2] with visible light, giving rise to C3-centre