Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Claudio Scuoppo"'
Autor:
Xiao Chen, Yinglu Li, Fang Zhu, Xinjing Xu, Brian Estrella, Manuel A. Pazos, John T. McGuire, Dimitris Karagiannis, Varun Sahu, Mustafo Mustafokulov, Claudio Scuoppo, Francisco J. Sánchez-Rivera, Yadira M. Soto-Feliciano, Laura Pasqualucci, Alberto Ciccia, Jennifer E. Amengual, Chao Lu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Interplay between chromatin-associated complexes and modifications critically contribute to the partitioning of epigenome into stable and functionally distinct domains. Yet there is a lack of systematic identification of chromatin crosstalk
Externí odkaz:
https://doaj.org/article/daa06f01dba548f4b57a4bb4e1ae71da
Autor:
Fiorella Scagnoli, Alessandro Palma, Annarita Favia, Claudio Scuoppo, Barbara Illi, Sergio Nasi
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 412 (2023)
MYC oncoprotein deregulation is a common catastrophic event in human cancer and limiting its activity restrains tumor development and maintenance, as clearly shown via Omomyc, an MYC-interfering 90 amino acid mini-protein. MYC is a multifunctional tr
Externí odkaz:
https://doaj.org/article/1da7b39c78e54af7b378606a1e41c766
Autor:
Chiara Ambrogio, Patrick Stern, Claudio Scuoppo, Harald Kranz, Mariano Barbacid, David Santamaría
Publikováno v:
BioTechniques, Vol 57, Iss 4, Pp 179-187 (2014)
Despite the pressing need for novel cancer treatments, our improved understanding of tumor biology is not being successfully translated into better therapies. Here we present a lentiviral vector that enables in vivo validation of cancer therapeutic t
Externí odkaz:
https://doaj.org/article/19972bc6aa174747995a49196454c916
Autor:
Samit Chatterjee, Laurie Seifried, Michael E Feigin, Don L Gibbons, Claudio Scuoppo, Wei Lin, Zain H Rizvi, Evan Lind, Dilan Dissanayake, Jonathan Kurie, Pam Ohashi, Senthil K Muthuswamy
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34343 (2012)
Changes in expression and localization of proteins that regulate cell and tissue polarity are frequently observed in carcinoma. However, the mechanisms by which changes in cell polarity proteins regulate carcinoma progression are not well understood.
Externí odkaz:
https://doaj.org/article/90a1cd0096e04306b3d2cda5a724962d
Autor:
Carola Ponzetto, Tiziana Crepaldi, Michel Schmitt-Ney, Paola Allegra, Alberto Grinza, Silvia Miretti, Paolo E. Forni, Paolo Accornero, Francesca Bersani, Claudio Scuoppo, Riccardo Taulli
Rhabdomyosarcoma (RMS) is a highly malignant soft-tissue tumor of childhood deriving from skeletal muscle cells. RMS can be classified in two major histologic subtypes: embryonal (ERMS) and alveolar (ARMS), the latter being characterized by the PAX3/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8430a487da43e3d19b0ce49c01d1020
https://doi.org/10.1158/0008-5472.c.6495062.v1
https://doi.org/10.1158/0008-5472.c.6495062.v1
Autor:
Carola Ponzetto, Tiziana Crepaldi, Michel Schmitt-Ney, Paola Allegra, Alberto Grinza, Silvia Miretti, Paolo E. Forni, Paolo Accornero, Francesca Bersani, Claudio Scuoppo, Riccardo Taulli
Supplementary Figure 1 from Validation of Met as a Therapeutic Target in Alveolar and Embryonal Rhabdomyosarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f206ce7d6ae0389fe3808a9b605004
https://doi.org/10.1158/0008-5472.22366256
https://doi.org/10.1158/0008-5472.22366256
Autor:
Carola Ponzetto, Tiziana Crepaldi, Michel Schmitt-Ney, Paola Allegra, Alberto Grinza, Silvia Miretti, Paolo E. Forni, Paolo Accornero, Francesca Bersani, Claudio Scuoppo, Riccardo Taulli
Supplementary Figure 2 from Validation of Met as a Therapeutic Target in Alveolar and Embryonal Rhabdomyosarcoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fde9f82d0dc9ddf8402533a8d5d60e2
https://doi.org/10.1158/0008-5472.22366253
https://doi.org/10.1158/0008-5472.22366253
Autor:
Rebecca J Brownlie, Ruth Kennedy, Erica B Wilson, Maja Milanovic, Claire F Taylor, Dapeng Wang, John Davies, Heather Elizabeth Owston, Emma J Adams, Sophie Stephenson, Rebecca Caeser, Benjamin E Gewurz, Peter V Giannoudis, Claudio Scuoppo, Dennis McGonagle, Daniel J Hodson, Reuben M Tooze, Gina M Doody, Gordon Cook, David R Westhead, Ulf Klein
Publikováno v:
Blood Advances.
Multiple myeloma (MM) shows constitutive activation of canonical and non-canonical nuclear factor-ĸB (NF-ĸB) signaling through genetic mutations or stimuli from the tumour microenvironment (TME). A subset of MM cell lines showed dependency for cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efd7a05ed7694f34e461dca36e4bc6a7
https://doi.org/10.1182/bloodadvances.2022009044
https://doi.org/10.1182/bloodadvances.2022009044
Autor:
Claudio Scuoppo, Gerald Falchook, Elisa Fontana, Anja Williams, Nehal Lakhani, Jeff Evans, Fabio Iwamoto, Meredith McKean, Stefan Symeonides, Alistair McLaren, Jason Henry, Gina Capiaux, Robert Michel, Stephen Kaesshaefer, Alice Bexon, Jim Rotolo
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ab30bf40c2462adf175c689b465d2aa
https://doi.org/10.1136/jitc-2022-sitc2022.1173
https://doi.org/10.1136/jitc-2022-sitc2022.1173
Autor:
Claudio Scuoppo, Lila Ghamsari, Erin Gallagher, Siok Leong, Mark Koester, Rick Ramirez, Jerel Gonzales, Gene Merutka, Barry Kappel, Abi Vainstein-Haras, Jim Rotolo
Publikováno v:
Cancer Research. 83:LB016-LB016
The transcription factor β-catenin is a key player in many cellular processes, including stem cell renewal, cellular homeostasis and inflammation. Deregulation of β-catenin occurs frequently in several cancer types by mutation or overexpression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a17c8a7878e33d64ac764d57f0c3b42
https://doi.org/10.1158/1538-7445.am2023-lb016
https://doi.org/10.1158/1538-7445.am2023-lb016