Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Claudio Santoro"'
Autor:
Damiano Mangoni, Alessandro Simi, Pierre Lau, Alexandros Armaos, Federico Ansaloni, Azzurra Codino, Devid Damiani, Lavinia Floreani, Valerio Di Carlo, Diego Vozzi, Francesca Persichetti, Claudio Santoro, Luca Pandolfini, Gian Gaetano Tartaglia, Remo Sanges, Stefano Gustincich
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Long Interspersed Nuclear Elements-1s (L1s) are transposable elements that constitute most of the genome’s transcriptional output yet have still largely unknown functions. Here we show that L1s are required for proper mouse brain corticoge
Externí odkaz:
https://doaj.org/article/66f2f44858894eb082807efecd36e486
Autor:
Bianca Pierattini, Sabrina D’Agostino, Carlotta Bon, Omar Peruzzo, Andrej Alendar, Azzurra Codino, Gloria Ros, Francesca Persichetti, Remo Sanges, Piero Carninci, Claudio Santoro, Stefano Espinoza, Paola Valentini, Luca Pandolfini, Stefano Gustincich
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 402-414 (2023)
SINEUPs are natural and synthetic antisense long non-coding RNAs (lncRNAs) selectively enhancing target mRNAs translation by increasing their association with polysomes. This activity requires two RNA domains: an embedded inverted SINEB2 element acti
Externí odkaz:
https://doaj.org/article/439e7dc3410e4a769903132bc7c5d494
Autor:
Claudio Santoro, Michela D'Oro
Publikováno v:
Pathos, Vol 29, Iss 3, Pp 7-15 (2022)
Cervicogenic headache is a common disorder affecting about 68 per cent of adults in Europe (53 per cent headache and 15 per cent migraine), of which around 2-5 per cent are chronically refractory.1 Patients who suffer from it are often induced to use
Externí odkaz:
https://doaj.org/article/8e55a49e6c0944e1ae0686fd2297833e
Autor:
Chiara Santulli, Carlotta Bon, Elena De Cecco, Marta Codrich, Joanna Narkiewicz, Pietro Parisse, Fabio Perissinotto, Claudio Santoro, Francesca Persichetti, Giuseppe Legname, Stefano Espinoza, Stefano Gustincich
Publikováno v:
Cell Death and Disease, Vol 13, Iss 12, Pp 1-12 (2022)
Abstract Parkinson’s disease (PD) presents the selective loss of A9 dopaminergic (DA) neurons of Substantia Nigra pars compacta (SNpc) and the presence of intracellular aggregates called Lewy bodies. α-synuclein (α-syn) species truncated at the c
Externí odkaz:
https://doaj.org/article/80bf628709704b4db31038a5f1387abc
Autor:
Casimiro Luca Gigliotti, Elena Boggio, Francesco Favero, Danny Incarnato, Claudio Santoro, Salvatore Oliviero, Josè Maria Rojo, Silvia Zucchelli, Francesca Persichetti, Gianluca Baldanzi, Umberto Dianzani, Davide Corà
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Costimulatory molecules of the CD28 family play a crucial role in the activation of immune responses in T lymphocytes, complementing and modulating signals originating from the T-cell receptor (TCR) complex. Although distinct functional roles have be
Externí odkaz:
https://doaj.org/article/55eb914dee7e467a8a6a4d3d915b6074
Autor:
Mara Gagliardi, Nausicaa Clemente, Romina Monzani, Luca Fusaro, Eleonora Ferrari, Valentina Saverio, Giovanna Grieco, Elżbieta Pańczyszyn, Flavia Carton, Claudio Santoro, Sara Del Mare-Roumani, Sivan Amidror, Nissan Yissachar, Francesca Boccafoschi, Silvia Zucchelli, Marco Corazzari
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Celiac disease (CD) is a complex immune-mediated chronic disease characterized by a consistent inflammation of the gastrointestinal tract induced by gluten intake in genetically predisposed individuals. Although initiated by the interaction
Externí odkaz:
https://doaj.org/article/6d68940d7e6942889c1d1acb6068e810
Publikováno v:
Pathos, Vol 28, Iss 3 (2021)
Low back pain is among the disorders with the greatest social and economic impact in the Western world. The present study refers to 182 requests for intervention for low back pain received by the Research Center of Mechanical Dysfunctions of Osteolab
Externí odkaz:
https://doaj.org/article/de7c12092a754c43be71df2954469eb8
Autor:
Romina Monzani, Mara Gagliardi, Nausicaa Clemente, Valentina Saverio, Elżbieta Pańczyszyn, Claudio Santoro, Nissan Yissachar, Annalisa Visciglia, Marco Pane, Angela Amoruso, Marco Corazzari
Publikováno v:
Biology, Vol 11, Iss 11, p 1574 (2022)
Background: IBD is a spectrum of pathologies characterized by dysregulated immune activation leading to uncontrolled response against the intestine, thus resulting in chronic gut inflammation and tissue damage. Due to its complexity, the molecular me
Externí odkaz:
https://doaj.org/article/4a15037f3ca0407c880f62e23aca5ef5
Autor:
Mathieu Ferrari, Shimobi C. Onuoha, Liliane Fossati-Jimack, Alessandra Nerviani, Pedro L. Alves, Sara Pagani, Cecilia Deantonio, Federico Colombo, Claudio Santoro, Daniele Sblattero, Costantino Pitzalis
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Biologic drugs, especially anti-TNF, are considered as the gold standard therapy in rheumatoid arthritis. However, non-uniform efficacy, incidence of infections, and high costs are major concerns. Novel tissue-specific agents may overcome the current
Externí odkaz:
https://doaj.org/article/8e51988c2b5b4d63861b2b90547439fa
Autor:
Maria Felicia Soluri, Simone Puccio, Giada Caredda, Paolo Edomi, Mario Milco D’Elios, Fabio Cianchi, Arianna Troilo, Claudio Santoro, Daniele Sblattero, Clelia Peano
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
The analysis of the interaction between Helicobacter pylori (HP) and the host in vivo is an extremely informative way to enlighten the molecular mechanisms behind the persistency/latency of the bacterium as well as in the progression of the infection
Externí odkaz:
https://doaj.org/article/e2021c8f3d42435a95df74b077ac5d9c