Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Claudio Perez"'
Autor:
Arian Mansur, Remi Joseph, Euri S Kim, Pierre M Jean-Beltran, Namrata D Udeshi, Cadence Pearce, Hanjie Jiang, Reina Iwase, Miroslav P Milev, Hashem A Almousa, Elyshia McNamara, Jeffrey Widrick, Claudio Perez, Gianina Ravenscroft, Michael Sacher, Philip A Cole, Steven A Carr, Vandana A Gupta
Publikováno v:
eLife, Vol 12 (2023)
Ubiquitin-proteasome system (UPS) dysfunction is associated with the pathology of a wide range of human diseases, including myopathies and muscular atrophy. However, the mechanistic understanding of specific components of the regulation of protein tu
Externí odkaz:
https://doaj.org/article/e9f154452fff4bc5b183818788e75991
Autor:
Yenniffer Ávalos, María Paz Hernández-Cáceres, Pablo Lagos, Daniela Pinto-Nuñez, Patricia Rivera, Paulina Burgos, Francisco Díaz-Castro, Michelle Joy-Immediato, Leslye Venegas-Zamora, Erik Lopez-Gallardo, Catalina Kretschmar, Ana Batista-Gonzalez, Flavia Cifuentes-Araneda, Lilian Toledo-Valenzuela, Marcelo Rodriguez-Peña, Jasson Espinoza-Caicedo, Claudio Perez-Leighton, Cristina Bertocchi, Mauricio Cerda, Rodrigo Troncoso, Valentina Parra, Mauricio Budini, Patricia V. Burgos, Alfredo Criollo, Eugenia Morselli
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-13 (2022)
Abstract Palmitic acid (PA) is significantly increased in the hypothalamus of mice, when fed chronically with a high-fat diet (HFD). PA impairs insulin signaling in hypothalamic neurons, by a mechanism dependent on autophagy, a process of lysosomal-m
Externí odkaz:
https://doaj.org/article/b47731c95f5542fbb628ad3b2b8ffa69
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 577 (2023)
The leading cause of death in psoriasis is cardiovascular disease. The determinants that induce the increase in this risk are not known. The systemic inflammatory process is dependent on lymphocytes and monocytes, as has been proposed. However, adapt
Externí odkaz:
https://doaj.org/article/7004a28c46b5496780d4a820d6e4e1f2
Publikováno v:
Metabolites, Vol 13, Iss 1, p 116 (2023)
Psoriasis is a skin disease with occasional involvement of non-cutaneous territories. Beyond the usual, cardiovascular events are more frequent in these patients and correlate only partially with disease activity, suggesting the presence of other unk
Externí odkaz:
https://doaj.org/article/d8f9952e1ab34a8e8a367892011b5df7
Autor:
María Paz Hernández-Cáceres, Karina Cereceda, Sergio Hernández, Ying Li, Carla Narro, Patricia Rivera, Patricio Silva, Yenniffer Ávalos, Claudia Jara, Paulina Burgos, Lilian Toledo-Valenzuela, Pablo Lagos, Flavia Cifuentes Araneda, Claudio Perez-Leighton, Cristina Bertocchi, Deborah J. Clegg, Alfredo Criollo, Cheril Tapia-Rojas, Patricia V. Burgos, Eugenia Morselli
Publikováno v:
Molecular & Cellular Oncology, Vol 7, Iss 5 (2020)
High-fat diet (HFD)-induced obesity is associated with increased cancer risk. Long-term feeding with HFD increases the concentration of the saturated fatty acid palmitic acid (PA) in the hypothalamus. We previously showed that, in hypothalamic neuron
Externí odkaz:
https://doaj.org/article/2cf149af5026454ba7c466f56d443a3e
Autor:
Killen García, Gisselle Escobar, Pablo Mendoza, Caroll Beltran, Claudio Perez, Sergio Arancibia, Rolando Vernal, Paula I. Rodas, Claudio Acuña-Castillo, Alejandro Escobar
Publikováno v:
Mediators of Inflammation, Vol 2016 (2016)
Neisseria gonorrhoeae (Ngo) has developed multiple immune evasion mechanisms involving the innate and adaptive immune responses. Recent findings have reported that Ngo reduces the IL-1β secretion of infected human monocyte-derived macrophages (MDM).
Externí odkaz:
https://doaj.org/article/adc01d9d57bd49c998cfdb62163cc4f7
Autor:
Juan Francisco Miquel, Eugenia Morales, Lorena Azocar, Ximena Maul, Claudio Perez, José Chianale
Publikováno v:
BMJ Open, Vol 1, Iss 1 (2011)
Background The lactase persistent (LP) or lactase non-persistent (LNP) state in European adults is genetically determined by a single nucleotide polymorphism (SNP) located 13.9 kb upstream of the lactase (LCT) gene, known as LCT C>T−13910 (rs498823
Externí odkaz:
https://doaj.org/article/31a8483acda64d0a94a1141c46d8500e
Autor:
José ORTS-CARDADOR, Jaime, Claudio PEREZ-GALVEZ, Jesús, Gómez-Casero FUENTES, Gema María, Jara ALBA, Carol Angélica
Publikováno v:
GeoJournal of Tourism & Geosites; 2024, Vol. 55 Issue 3, p1164-1173, 10p
Autor:
Pamela Mattar, Lilian Toledo‐Valenzuela, María Paz Hernández‐Cáceres, Daniel Peña‐Oyarzún, Eugenia Morselli, Claudio Perez‐Leighton
Publikováno v:
Obesity. 30:1143-1155
Excess dietary sucrose is associated with obesity and metabolic diseases. This relationship is driven by the malfunction of several cell types and tissues critical for the regulation of energy balance, including hypothalamic neurons and white adipose
Autor:
Arian Mansur, Remi Joseph, Pierre Michael Jean-Beltran, Namrata D. Udeshi, Cadence Pearce, Hanjie Jiang, Reina Iwase, Elyshia McNamara, Jeff Widrick, Claudio Perez, Gianina Ravenscroft, Philip A Cole, Steven A Carr, Vandana A Gupta
Ubiquitin-proteasome system (UPS) dysfunction is associated with the pathology of a wide range of human diseases including myopathies and muscular atrophy. However, the mechanistic understanding of specific components on the regulation of protein tur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4805886ece0fd7328d53f492f8e0307c
https://doi.org/10.1101/2022.07.21.501000
https://doi.org/10.1101/2022.07.21.501000