Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Claudio Omini"'
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 348:213-219
Intratracheal Parainfluenza type 3 (PI-3) virus inoculation of guinea pigs leads to a non-specific airway hyperresponsiveness in vivo and in vitro which coincides with a significant increase in the number of inflammatory cells in the broncho-alveolar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0a5e32cdadaebb26263b6b9663f2747
https://doi.org/10.1007/bf00164801
https://doi.org/10.1007/bf00164801
Publikováno v:
European Journal of Pharmacology: Environmental Toxicology and Pharmacology. 228:257-261
We verified the possible effect of the new antitussive drug levodropropizine on airway hyperreactivity and lung inflammation induced by cigarette smoke exposure in anaesthetized guinea-pigs. Levodropropizine, administered by aerosol at 25 mg/ml for 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10d844dccedf30ccf4bf6d182e8418c
https://doi.org/10.1016/0926-6917(93)90058-x
https://doi.org/10.1016/0926-6917(93)90058-x
Publikováno v:
Pharmacological Research. 23:57-69
Summary The α -adrenoceptor populations in aortic strips from humans, rats, guinea-pigs and rabbits were investigated in vitro , using specific agonists and antagonists. In rabbit and human preparations the activities of the two agonists tested, nor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d5449e17a7c2a558fe552191ecbf52
https://doi.org/10.1016/s1043-6618(05)80107-0
https://doi.org/10.1016/s1043-6618(05)80107-0
Autor:
Pierangelo Geppetti, Jay A. Nadel, Luisa Daffonchio, Olivier Huber, Claude Bertrand, Claudio Omini, Isao Yamawaki
Publikováno v:
European journal of pharmacology. 243(1)
We investigated the effect of the non-opioid, peripherally acting antitussive agent levodropropizine to reduce neurogenic plasma extravasation in the rat trachea. Levodropropizine (10, 50 and 200 mg/kg) reduced in a dose-dependent manner the extravas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ebd9478491220b308b27fc3247bd229
https://pubmed.ncbi.nlm.nih.gov/7504629
https://pubmed.ncbi.nlm.nih.gov/7504629
1. In anaesthetized, actively sensitized guinea-pigs, the anaphylactic shock induced by antigen aerosol challenge (5 s; 50 mg ml-1) was followed by increase in airway reactivity to both acetylcholine and substance P. In particular dose-response curve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6789a8d8e8b854977e1d1c33db978f
http://hdl.handle.net/11568/173761
http://hdl.handle.net/11568/173761
Publikováno v:
Pharmacological research. 24(4)
Interleukin-1 (IL-1), a peptide released from monocytes/macrophages, plays an important role in the inflammatory and immune responses. Airway hyperreactivity and the underlying airway inflammation are common features in asthma pathology. We investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63aca2245f79a6a607ed804bbfbcc7d1
https://pubmed.ncbi.nlm.nih.gov/1805192
https://pubmed.ncbi.nlm.nih.gov/1805192
Publikováno v:
Journal of Autonomic Pharmacology. 2:247-253
1 The formation and release of PGE2-like material (PGE2-lm) from guinea-pig isolated trachea and human bronchi following relaxation with isoprenaline (I) was investigated. 2 When airway smooth muscle precontracted with pilocarpine is relaxed by I, PG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bb8bc585bd0ef4f9111e15b806ab1cd
https://doi.org/10.1111/j.1474-8673.1982.tb00516.x
https://doi.org/10.1111/j.1474-8673.1982.tb00516.x
Publikováno v:
British Journal of Pharmacology. 65:629-633
1. When isolated perfused lungs from normal and ovalbumin sensitized guinea-pigs were challenged with histamine and 2-methylhistamine (agonists for H1-receptor), a release of thromboxane A2-like substance was observed. The effect of histamine on prod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb540a8cf4c03e337d19f9aeda33c9b6
https://doi.org/10.1111/j.1476-5381.1979.tb07874.x
https://doi.org/10.1111/j.1476-5381.1979.tb07874.x
Publikováno v:
Neuroscience. 15:563-575
A 15,000 dalton polypeptide purified from Bungarus multicinctus venom (which normally copurifies with alpha-bungarotoxin) was characterized biochemically and its biological effects were studied. This polypeptide, P15, had an aminoacid composition and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6a66e630d5cd4edc6ff323e84fe096
https://doi.org/10.1016/0306-4522(85)90234-9
https://doi.org/10.1016/0306-4522(85)90234-9
Publikováno v:
European Journal of Pharmacology. 78:159-165
Various doses of histamine, bradykinin and leukotriene C 4 caused bronchoconstriction in anaesthetized guinea-pigs which were breathing spontaneously or artificially ventilated; there was a simultaneous, dose-related increase of circulating TXA 2 . T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7be715b8e38dbf6effb6dd3591c424bf
https://doi.org/10.1016/0014-2999(82)90232-1
https://doi.org/10.1016/0014-2999(82)90232-1