Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Claudio N Cavasotto"'
Autor:
Yeon-Tae Jeong, Daniele Simoneschi, Sarah Keegan, David Melville, Natalia S Adler, Anita Saraf, Laurence Florens, Michael P Washburn, Claudio N Cavasotto, David Fenyö, Ana Maria Cuervo, Mario Rossi, Michele Pagano
Publikováno v:
eLife, Vol 7 (2018)
In response to nutrient deprivation, the cell mobilizes an extensive amount of membrane to form and grow the autophagosome, allowing the progression of autophagy. By providing membranes and stimulating LC3 lipidation, COPII (Coat Protein Complex II)
Externí odkaz:
https://doaj.org/article/d20336fa41b346ddb8b57f83a6370609
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189454 (2017)
[This corrects the article DOI: 10.1371/journal.pone.0024563.].
Externí odkaz:
https://doaj.org/article/7a439228089a4657bc8770e888cdf089
Autor:
Rosa Doménech, José G Hernández-Cifre, Julio Bacarizo, Ana I Díez-Peña, Sergio Martínez-Rodríguez, Claudio N Cavasotto, José García de la Torre, Ana Cámara-Artigás, Adrián Velázquez-Campoy, José L Neira
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69307 (2013)
The phosphotransferase system (PTS) is involved in the use of carbon sources in bacteria. Bacillus sphaericus, a bacterium with the ability to produce insecticidal proteins, is unable to use hexoses and pentoses as the sole carbon source, but it has
Externí odkaz:
https://doaj.org/article/abd4c8b580334ecd9f3a2594e2905d10
Autor:
Indrani Dasgupta, Eric A Tanifum, Mayank Srivastava, Sharangdhar S Phatak, Claudio N Cavasotto, Mostafa Analoui, Ananth Annapragada
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29585 (2012)
Boronic acids, known to bind diols, were screened to identify non-inflammatory cross-linkers for the preparation of glucose sensitive and insulin releasing agglomerates of liposomes (Agglomerated Vesicle Technology-AVT). This was done in order to sel
Externí odkaz:
https://doaj.org/article/082412c9501449799387a163ffd5d043
Autor:
Rebeca Bocanegra, María Nevot, Rosa Doménech, Inmaculada López, Olga Abián, Alicia Rodríguez-Huete, Claudio N Cavasotto, Adrián Velázquez-Campoy, Javier Gómez, Miguel Ángel Martínez, José Luis Neira, Mauricio G Mateu
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e23877 (2011)
Virus capsid assembly constitutes an attractive target for the development of antiviral therapies; a few experimental inhibitors of this process for HIV-1 and other viruses have been identified by screening compounds or by selection from chemical lib
Externí odkaz:
https://doaj.org/article/f05692aa4e6b4c5689ff07931322ec5e
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24563 (2011)
In this work, we introduce an algorithm to compute the derivatives of physical observables along the constrained subspace when flexible constraints are imposed on the system (i.e., constraints in which the constrained coordinates are fixed to configu
Externí odkaz:
https://doaj.org/article/b7808e73b7a0479ebf909bb5f9d7e6cd
Autor:
Claudio N. Cavasotto, Valeria Scardino
Publikováno v:
ACS Omega, Vol 7, Iss 51, Pp 47536-47546 (2022)
Externí odkaz:
https://doaj.org/article/346378e1f6e74209b14724be49eca6fa
Publikováno v:
iScience, Vol 26, Iss 1, Pp 105920- (2023)
Summary: A crucial component in structure-based drug discovery is the availability of high-quality three-dimensional structures of the protein target. Whenever experimental structures were not available, homology modeling has been, so far, the method
Externí odkaz:
https://doaj.org/article/8d78f8b9f771471e83609218ee4619d3
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
The development of computational models for assessing the transfer of chemicals across the placental membrane would be of the utmost importance in drug discovery campaigns, in order to develop safe therapeutic options. We have developed a low-dimensi
Externí odkaz:
https://doaj.org/article/5c73f82959474be287b3ab052f4a6e09
Publikováno v:
Journal of Chemical Information and Modeling. 63:2267-2280
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6218e6524a32d5a6670f33574605f34
https://doi.org/10.1021/acs.jcim.2c01471
https://doi.org/10.1021/acs.jcim.2c01471