Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Claudio Lo Giudice"'
Autor:
Anna Lavecchia, Caterina Manzari, Chrysovalentinos Pousis, Luigi Mansi, Sharon N. Cox, Constantinos C. Mylonas, Rosa Zupa, Claudio Lo Giudice, Caterina De Virgilio, Ernesto Picardi, Gianluca Ventriglia, Graziano Pesole, Aldo Corriero
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Reproductive dysfunctions have been recently documented in male greater amberjack Seriola dumerili caught from the wild and reared in captivity. In the present study, we compared testis transcriptome in wild fish (WILD), hatchery-produced fi
Externí odkaz:
https://doaj.org/article/ebea80ec06484617978e21509fcec46b
Autor:
Sharon Natasha Cox, Claudio Lo Giudice, Anna Lavecchia, Maria Luana Poeta, Matteo Chiara, Ernesto Picardi, Graziano Pesole
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 411 (2024)
Amyotrophic Lateral Sclerosis (ALS) is a progressive disease with prevalent mitochondrial dysfunctions affecting both upper and lower motor neurons in the motor cortex, brainstem, and spinal cord. Despite mitochondria having their own genome (mtDNA),
Externí odkaz:
https://doaj.org/article/e97ff24d73374897957f631d12fb334f
Autor:
Riccardo Pecori, Isabel Chillón, Claudio Lo Giudice, Annette Arnold, Sandra Wüst, Marco Binder, Marco Marcia, Ernesto Picardi, Fotini Nina Papavasiliou
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Despite hundreds of RNA modifications described to date, only RNA editing results in a change in the nucleotide sequence of RNA molecules compared to the genome. In mammals, two kinds of RNA editing have been described so far, adenosine to inosine (A
Externí odkaz:
https://doaj.org/article/0a436a508c1a41ffa1230acaf8099786
Autor:
Domenica Lovero, Damiano Porcelli, Luca Giordano, Claudio Lo Giudice, Ernesto Picardi, Graziano Pesole, Eugenia Pignataro, Antonio Palazzo, René Massimiliano Marsano
Publikováno v:
Biology, Vol 12, Iss 8, p 1127 (2023)
Gene and genome comparison represent an invaluable tool to identify evolutionarily conserved sequences with possible functional significance. In this work, we have analyzed orthologous genes encoding subunits and assembly factors of the V-ATPase comp
Externí odkaz:
https://doaj.org/article/0768520fc48a473f80dcdcd0cdb826fd
Autor:
Alessandra Costanza, Nicoletta Guaragnella, Antonella Bobba, Caterina Manzari, Alberto L’Abbate, Claudio Lo Giudice, Ernesto Picardi, Anna Maria D’Erchia, Graziano Pesole, Sergio Giannattasio
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Mutations in BRCA2 gene increase the risk for breast cancer and for other cancer types, including pancreatic and prostate cancer. Since its first identification as an oncosupressor in 1995, the best-characterized function of BRCA2 is in the repair of
Externí odkaz:
https://doaj.org/article/308cbf1a4c1c4ac38d0cfe035fe74ae2
Autor:
Alfonso Monaco, Ester Pantaleo, Nicola Amoroso, Antonio Lacalamita, Claudio Lo Giudice, Adriano Fonzino, Bruno Fosso, Ernesto Picardi, Sabina Tangaro, Graziano Pesole, Roberto Bellotti
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 4345-4359 (2021)
High throughput sequencing technologies have enabled the study of complex biological aspects at single nucleotide resolution, opening the big data era. The analysis of large volumes of heterogeneous “omic” data, however, requires novel and effici
Externí odkaz:
https://doaj.org/article/fd79c26be4bf4620b9ecac17d86a7522
Autor:
Claudio Lo Giudice, Domenico Alessandro Silvestris, Shalom Hillel Roth, Eli Eisenberg, Graziano Pesole, Angela Gallo, Ernesto Picardi
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Massive transcriptome sequencing through the RNAseq technology has enabled quantitative transcriptome-wide investigation of co-/post-transcriptional mechanisms such as alternative splicing and RNA editing. The latter is abundant in human transcriptom
Externí odkaz:
https://doaj.org/article/71f8fd4c17054856b761ea76504259c8
Publikováno v:
Frontiers in Plant Science, Vol 9 (2018)
RNA editing is an important epigenetic mechanism by which genome-encoded transcripts are modified by substitutions, insertions and/or deletions. It was first discovered in kinetoplastid protozoa followed by its reporting in a wide range of organisms.
Externí odkaz:
https://doaj.org/article/4468ec9dda4143b98137bbf11eb189df
Autor:
Renata Kleinova, Vinod Rajendra, Alina F Leuchtenberger, Claudio Lo Giudice, Cornelia Vesely, Utkarsh Kapoor, Andrea Tanzer, Sophia Derdak, Ernesto Picardi, Michael F Jantsch
Publikováno v:
Nucleic Acids Research. 51:4191-4207
Adenosine deaminase acting on RNA ADAR1 promotes A-to-I conversion in double-stranded and structured RNAs. ADAR1 has two isoforms transcribed from different promoters: cytoplasmic ADAR1p150 is interferon-inducible while ADAR1p110 is constitutively ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f1ac4e168818703b883b00914a6ae02
https://doi.org/10.1093/nar/gkad265
https://doi.org/10.1093/nar/gkad265
Autor:
Nicola Amoroso, Claudio Lo Giudice, Ernesto Picardi, Adriano Fonzino, Alfonso Monaco, Bruno Fosso, Ester Pantaleo, Graziano Pesole, Sabina Tangaro, Antonio Lacalamita, Roberto Bellotti
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4345-4359 (2021)
Computational and Structural Biotechnology Journal 19 (2021): 4345–4359. doi:10.1016/j.csbj.2021.07.021
info:cnr-pdr/source/autori:Monaco, Alfonso; Pantaleo, Ester; Amoroso, Nicola; Lacalamita, Antonio; Lo Giudice, Claudio; Fonzino, Adriano; Fosso, Bruno; Picardi, Ernesto; Tangaro, Sabina; Pesole, Graziano; Bellotti, Roberto/titolo:A primer on machine learning techniques for genomic applications/doi:10.1016%2Fj.csbj.2021.07.021/rivista:Computational and Structural Biotechnology Journal/anno:2021/pagina_da:4345/pagina_a:4359/intervallo_pagine:4345–4359/volume:19
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal 19 (2021): 4345–4359. doi:10.1016/j.csbj.2021.07.021
info:cnr-pdr/source/autori:Monaco, Alfonso; Pantaleo, Ester; Amoroso, Nicola; Lacalamita, Antonio; Lo Giudice, Claudio; Fonzino, Adriano; Fosso, Bruno; Picardi, Ernesto; Tangaro, Sabina; Pesole, Graziano; Bellotti, Roberto/titolo:A primer on machine learning techniques for genomic applications/doi:10.1016%2Fj.csbj.2021.07.021/rivista:Computational and Structural Biotechnology Journal/anno:2021/pagina_da:4345/pagina_a:4359/intervallo_pagine:4345–4359/volume:19
Computational and Structural Biotechnology Journal
Graphical abstract
High throughput sequencing technologies have enabled the study of complex biological aspects at single nucleotide resolution, opening the big data era. The analysis of large volumes of heterogeneous “omic” data, however, r
High throughput sequencing technologies have enabled the study of complex biological aspects at single nucleotide resolution, opening the big data era. The analysis of large volumes of heterogeneous “omic” data, however, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0ff3556df8abc03459f6890b5eedee
http://www.sciencedirect.com/science/article/pii/S2001037021003111
http://www.sciencedirect.com/science/article/pii/S2001037021003111