Zobrazeno 1 - 10
of 232
pro vyhledávání: '"Claudio Festuccia"'
Autor:
Simona Camero, Luisa Milazzo, Francesca Vulcano, Federica Ceccarelli, Paola Pontecorvi, Francesca Pedini, Alessandra Rossetti, Elena Sofia Scialis, Giulia Gerini, Fabrizio Cece, Silvia Pomella, Matteo Cassandri, Antonella Porrazzo, Enrico Romano, Claudio Festuccia, Giovanni Luca Gravina, Simona Ceccarelli, Rossella Rota, Lavinia Vittoria Lotti, Fabio Midulla, Antonio Angeloni, Cinzia Marchese, Francesco Marampon, Francesca Megiorni
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-24 (2024)
Abstract Background Despite a multimodal approach including surgery, chemo- and radiotherapy, the 5-year event-free survival rate for rhabdomyosarcoma (RMS), the most common soft tissue sarcoma in childhood, remains very poor for metastatic patients,
Externí odkaz:
https://doaj.org/article/0b81896720af4a4a9845e88f03e04c18
Autor:
Alessandra Rossetti, Louis Chonco, Nicolas Alegría, Veronica Zelli, Andrés J. García, Carmen Ramírez-Castillejo, Alessandra Tessitore, Carlos de Cabo, Tomás Landete-Castillejos, Claudio Festuccia
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 610 (2024)
Deer antlers are the fastest growing tissue. Because they are based on proto-oncogenes, to avoid the risk of cancer, antlers evolved strong anticancer mechanisms, and thus their extract (DVA) is effective also against the few human tumours studied so
Externí odkaz:
https://doaj.org/article/5da592357b1443e2ae67c603adf7d2b4
Autor:
Claudio Festuccia, Miriam Corrado, Alessandra Rossetti, Riccardo Castelli, Alessio Lodola, Giovanni Luca Gravina, Massimiliano Tognolini, Carmine Giorgio
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1452 (2023)
The Eph kinases are the largest receptor tyrosine kinases (RTKs) family in humans. PC3 human prostate adenocarcinoma cells are a well-established model for studying Eph–ephrin pharmacology as they naturally express a high level of EphA2, a promisin
Externí odkaz:
https://doaj.org/article/3a9195acd46340b580e53587f6f6d3b0
Autor:
Sara Vaccaro, Alessandra Rossetti, Antonella Porrazzo, Simona Camero, Matteo Cassandri, Silvia Pomella, Miriam Tomaciello, Giampiero Macioce, Francesca Pedini, Giovanni Barillari, Cinzia Marchese, Rossella Rota, Giovanni Cenci, Mario Tombolini, Robert A. Newman, Peiying Yang, Silvia Codenotti, Alessandro Fanzani, Francesca Megiorni, Claudio Festuccia, Giuseppe Minniti, Giovanni Luca Gravina, Francesca Vulcano, Luisa Milazzo, Francesco Marampon
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Treatment of rhabdomyosarcoma (RMS), the most common a soft tissue sarcoma in childhood, provides intensive multimodal therapy, with radiotherapy (RT) playing a critical role for local tumor control. However, since RMS efficiently activates mechanism
Externí odkaz:
https://doaj.org/article/35544f0854274470951c3529077bc1d1
Autor:
Andrea Mancini, Alessandro Colapietro, Loredana Cristiano, Alessandra Rossetti, Vincenzo Mattei, Giovanni Luca Gravina, Héctor Perez-Montoyo, Marc Yeste-Velasco, Jose Alfon, Carles Domenech, Claudio Festuccia
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundGlioblastoma multiforme (GBM) is the most malignant adult brain tumor. Current standard of care treatments have very limited efficacy, being the patients´ overall survival 14 months and the 2-year survival rate less than 10%. Therefore, th
Externí odkaz:
https://doaj.org/article/cb7a5d13492143b0b02a9cc3d74d5cbd
Autor:
Alessandro Colapietro, Peiying Yang, Alessandra Rossetti, Andrea Mancini, Flora Vitale, Sharmistha Chakraborty, Stefano Martellucci, Francesco Marampon, Vincenzo Mattei, Giovanni Luca Gravina, Roberto Iorio, Robert A. Newman, Claudio Festuccia
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Glioblastoma multiforme (GBM) is the most common as well as one of the most malignant types of brain cancer. Despite progress in development of novel therapies for the treatment of GBM, it remains largely incurable with a poor prognosis and a very lo
Externí odkaz:
https://doaj.org/article/b13f2ebbb77347bdb1a00a5f27f9b430
Autor:
Francesco Petragnano, Ilaria Pietrantoni, Simona Camero, Silvia Codenotti, Luisa Milazzo, Francesca Vulcano, Giampiero Macioce, Ilenia Giordani, Paolo Tini, Sara Cheleschi, Giovanni Luca Gravina, Claudio Festuccia, Alessandra Rossetti, Simona Delle Monache, Alessandra Ordinelli, Carmela Ciccarelli, Annunziata Mauro, Barboni Barbara, Cristina Antinozzi, Amalia Schiavetti, Roberto Maggio, Luigi Di Luigi, Antonella Polimeni, Cinzia Marchese, Vincenzo Tombolini, Alessandro Fanzani, Nicola Bernabò, Francesca Megiorni, Francesco Marampon
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-18 (2020)
Abstract Background The probability of local tumor control after radiotherapy (RT) remains still miserably poor in pediatric rhabdomyosarcoma (RMS). Thus, understanding the molecular mechanisms responsible of tumor relapse is essential to identify pe
Externí odkaz:
https://doaj.org/article/6c60768f760542368bab33f512e1c44b
Autor:
Sabrina Petricca, Giuseppe Celenza, Carla Luzi, Benedetta Cinque, Anna Rita Lizzi, Nicola Franceschini, Claudio Festuccia, Roberto Iorio
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5429 (2022)
Triazole and imidazole fungicides represent an emerging class of pollutants with endocrine-disrupting properties. Concerning mammalian reproduction, a possible causative role of antifungal compounds in inducing toxicity has been reported, although cu
Externí odkaz:
https://doaj.org/article/e2c8dfe966b34b39a0f7ee5e405fc552
Autor:
Alessandro Colapietro, Peiying Yang, Alessandra Rossetti, Andrea Mancini, Flora Vitale, Stefano Martellucci, Tara L. Conway, Sharmistha Chakraborty, Francesco Marampon, Vincenzo Mattei, Giovanni Luca Gravina, Assunta Leda Biordi, Daoyan Wei, Robert A. Newman, Claudio Festuccia
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Glioblastoma multiform (GBM) is the most common primary glial tumor resulting in very low patient survival despite current extensive therapeutic efforts. Emerging evidence suggests that more effective treatments are required to overcome tumor heterog
Externí odkaz:
https://doaj.org/article/d2c9a214cbf44de9878f28120ccd6a82
Autor:
Antonella Vetuschi, Simona Pompili, Gian Piero Di Marco, Federico Calvaruso, Enzo Iacomino, Lidia Angelosante, Claudio Festuccia, Alessandro Colapietro, Roberta Sferra
Publikováno v:
European Journal of Histochemistry, Vol 64, Iss 1 (2020)
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent sinonasal mucosa inflammatory disease with still unclear pathophysiologic mechanisms that imply events of tissue repair and structural remodelling. Several cascades seem to have a cons
Externí odkaz:
https://doaj.org/article/3855442dacc04e14ac6499e0dd63a005