Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Claudio Elgueta-Karstegl"'
Publikováno v:
PLoS Pathogens, Vol 7, Iss 7, p e1002164 (2011)
Type 1 Epstein-Barr virus (EBV) strains immortalize B lymphocytes in vitro much more efficiently than type 2 EBV, a difference previously mapped to the EBNA-2 locus. Here we demonstrate that the greater transforming activity of type 1 EBV correlates
Externí odkaz:
https://doaj.org/article/859fd74648cb41b6bcb4bfcde741c9e8
Autor:
Bryan R. Cullen, Rachel Bosshard, Paul J. Farrell, Elizabeth A Boulden, Patrick C. Rämer, Christian Münz, Rebecca L. Skalsky, Goran Gregorovic, Cornelia Gujer, Claudio Elgueta Karstegl
Publikováno v:
Journal of Virology
Functions of Epstein-Barr virus (EBV)-encoded RNAs (EBERs) were tested in lymphoblastoid cell lines containing EBER mutants of EBV. Binding of EBER1 to ribosomal protein L22 (RPL22) was confirmed. Deletion of EBER1 or EBER2 correlated with increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921da6a595efb43ac0cf4aedc5d7630f
https://doi.org/10.1128/jvi.01873-15
https://doi.org/10.1128/jvi.01873-15
Autor:
Samantha, Correia, Anne, Palser, Claudio, Elgueta Karstegl, Jaap M, Middeldorp, Octavia, Ramayanti, Jeffrey I, Cohen, Allan, Hildesheim, Maria Dolores, Fellner, Joelle, Wiels, Robert E, White, Paul, Kellam, Paul J, Farrell
Publikováno v:
Journal of Virology
Viral gene sequences from an enlarged set of about 200 Epstein-Barr virus (EBV) strains, including many primary isolates, have been used to investigate variation in key viral genetic regions, particularly LMP1, Zp, gp350, EBNA1, and the BART microRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac409846233b141db16d5bfe283a0e23
https://pubmed.ncbi.nlm.nih.gov/28515295
https://pubmed.ncbi.nlm.nih.gov/28515295
Autor:
Michelle J. West, Claudio Elgueta Karstegl, Paulo B. Correia, Laila Cancian, Michael J. McClellan, Julian Cano-Flanagan, Stelios Tzellos, Paul J. Farrell
Publikováno v:
Journal of Virology. 88:8743-8753
Sequence differences in the EBNA-2 protein mediate the superior ability of type 1 Epstein-Barr virus (EBV) to transform human B cells into lymphoblastoid cell lines compared to that of type 2 EBV. Here we show that changing a single amino acid (S442D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbb72d0da53c02ab27f27040d67b18c1
https://doi.org/10.1128/jvi.01000-14
https://doi.org/10.1128/jvi.01000-14
Autor:
Carla Brandão, Carina Pereira, Mário Dinis-Ribeiro, Claudio Elgueta-Karstegl, Joana Silva, Paul J. Farrell, Hugo Sousa, Rui Medeiros
Publikováno v:
Molecular Carcinogenesis. 53:E92-E95
Up-regulation of cyclooxygenase-2 (COX-2) is an early and key event in human colorectal carcinogenesis (CRC). Nevertheless, the molecular mechanisms leading to this over-expression are largely unknown. We previously reported an association between th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e426c4a59c8bca638da474e487a58d27
https://doi.org/10.1002/mc.22049
https://doi.org/10.1002/mc.22049
Publikováno v:
Journal of General Virology. 91:622-629
Ten novel mutations were introduced into the Zp promoter to test the role of sequences outside the established transcription factor-binding sites in Epstein-Barr virus (EBV) reactivation. Most of these had only small effects, but mutations in the ZID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad466cabdbd389196cbb279a8580c2c2
https://doi.org/10.1099/vir.0.017277-0
https://doi.org/10.1099/vir.0.017277-0
Autor:
Ulrich K. Binné, Helen E. Bryant, Claudio Elgueta Karstegl, Paul J. Farrell, Peter J. Jenkins, Wolfgang Amon
Publikováno v:
Journal of Virology. 78:13460-13469
Episomal reporter plasmids containing the Epstein-Barr virus (EBV) oriP sequence stably transfected into Akata Burkitt's lymphoma cells were used to analyze EBV lytic cycle gene regulation. First, we found that the Zp promoter of EBV, but not the Rp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29fd3fb2e8ab39ee42384a7b861f988b
https://doi.org/10.1128/jvi.78.24.13460-13469.2004
https://doi.org/10.1128/jvi.78.24.13460-13469.2004
Autor:
Paul J. Farrell, Peter J. Jenkins, Martine Hollyoake, Albert Stühler, Barbara Wensing, Claudio Elgueta Karstegl
Publikováno v:
Journal of Virology. 75:6235-6241
Most of the Epstein-Barr virus genome in latently infected cells is in a standard nucleosomal structure, but the region encompassing oriP and the Epstein-Barr virus-encoded small RNA (EBER) genes shows a distinctive pattern when digested with microco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78f7933f601d168ef2d060b2bc7d52e4
https://doi.org/10.1128/jvi.75.13.6235-6241.2001
https://doi.org/10.1128/jvi.75.13.6235-6241.2001
Autor:
Orlando de Jesus, Martine Hollyoake, Yilong Wang, David J. Turner, Paul R. Smith, S. Diane Hayward, Beverly E. Griffin, Paul J. Farrell, L. Karran, Claudio Elgueta Karstegl
Publikováno v:
Journal of Virology. 74:3082-3092
CST (BART BARF0) family viral RNAs are expressed in several types of Epstein-Barr virus (EBV) infection, including EBV-associated cancers. Many different spliced forms of these RNAs have been described; here we have clarified the structures of some o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49e48f65e9f2043ebd1c8bea36315bd
https://doi.org/10.1128/jvi.74.7.3082-3092.2000
https://doi.org/10.1128/jvi.74.7.3082-3092.2000
Autor:
Mary Holman, Gerry G. B. Klaus, Caroline Johnson-Léger, Claudio Elgueta-Karstegl, Christopher J. Atkins
Publikováno v:
European Journal of Immunology. 27:2749-2756
CBA/N (xid) mice have a point mutation in Bruton's tyrosine kinase (btk), which results in their failure to respond to T-independent type 2 (TI-2) antigens, and to several B cell mitogens [most notably anti-immunoglobulin (Ig)] in vitro. They have re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cee85e1979666986cf0de4e9884cf8e
https://doi.org/10.1002/eji.1830271102
https://doi.org/10.1002/eji.1830271102