Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Claudio Cantú"'
Autor:
Lovisa Örkenby, Signe Skog, Helen Ekman, Alessandro Gozzo, Unn Kugelberg, Rashmi Ramesh, Srivathsa Magadi, Gianluca Zambanini, Anna Nordin, Claudio Cantú, Daniel Nätt, Anita Öst
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 5, Pp 1-17 (2023)
Abstract Early‐life stress can result in life‐long effects that impact adult health and disease risk, but little is known about how such programming is established and maintained. Here, we show that such epigenetic memories can be initiated in th
Externí odkaz:
https://doaj.org/article/086c71ff79a04aacae7639a3e759f974
Autor:
Pierfrancesco Pagella, Chai Foong Lai, Laurence Pirenne, Claudio Cantù, Martin E. Schwab, Thimios A. Mitsiadis
Publikováno v:
International Journal of Oral Science, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Neurite outgrowth inhibitor A (Nogo-A) is a major player in neural development and regeneration and the target of clinical trials aiming at promoting the regeneration of the central nervous system upon traumatic and ischemic injury. In this
Externí odkaz:
https://doaj.org/article/7a38e332226d460cab7be7e913df6316
Autor:
Sandhya Malla, Kanchan Kumari, Carlos A. García-Prieto, Jonatan Caroli, Anna Nordin, Trinh T. T. Phan, Devi Prasad Bhattarai, Carlos Martinez-Gamero, Eshagh Dorafshan, Stephanie Stransky, Damiana Álvarez-Errico, Paulina Avovome Saiki, Weiyi Lai, Cong Lyu, Ludvig Lizana, Jonathan D. Gilthorpe, Hailin Wang, Simone Sidoli, Andre Mateus, Dung-Fang Lee, Claudio Cantù, Manel Esteller, Andrea Mattevi, Angel-Carlos Roman, Francesca Aguilo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Lysine-specific histone demethylase 1 (LSD1), which demethylates mono- or di- methylated histone H3 on lysine 4 (H3K4me1/2), is essential for early embryogenesis and development. Here we show that LSD1 is dispensable for mouse embryonic stem
Externí odkaz:
https://doaj.org/article/2d6f847ecfc84532b688deb0fc0250d8
Akademický článek
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Autor:
Valentina Pastori, Gianluca Zambanini, Elisabetta Citterio, Tamina Weiss, Yukio Nakamura, Claudio Cantù, Antonella Ellena Ronchi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The identification of regulatory networks contributing to fetal/adult gene expression switches is a major challenge in developmental biology and key to understand the aberrant proliferation of cancer cells, which often reactivate fetal oncog
Externí odkaz:
https://doaj.org/article/cd5df03e21614dc0a1c64e70f659eeef
Autor:
Pierfrancesco Pagella, Chai Foong Lai, Laurence Pirenne, Claudio Cantù, Martin E. Schwab, Thimios A. Mitsiadis
Publikováno v:
International Journal of Oral Science, Vol 16, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/0e851615e72b4565a6533056e360a362
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-18 (2023)
Abstract Background Cleavage Under Targets and Release Using Nuclease (CUT&RUN) is an increasingly popular technique to map genome-wide binding profiles of histone modifications, transcription factors, and co-factors. The ENCODE project and others ha
Externí odkaz:
https://doaj.org/article/186487b8127e425a89cf1cb77949d05f
Autor:
Johanna Diener, Arianna Baggiolini, Mattias Pernebrink, Damian Dalcher, Luigi Lerra, Phil F. Cheng, Sandra Varum, Jessica Häusel, Salome Stierli, Mathias Treier, Lorenz Studer, Konrad Basler, Mitchell P. Levesque, Reinhard Dummer, Raffaella Santoro, Claudio Cantù, Lukas Sommer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Melanoma cells can switch between proliferative and invasive phenotypes. Here the authors show that the embryonic stem cell factor Sall4 is a negative regulator of melanoma phenotype switching where its loss leads to the acquisition of an invasive ph
Externí odkaz:
https://doaj.org/article/660bf2af02d44967be0835d0819d4414
Autor:
Nikolaos Doumpas, Simon Söderholm, Smarth Narula, Steven Moreira, Bradley W. Doble, Claudio Cantù, Konrad Basler
Publikováno v:
Cell Reports, Vol 36, Iss 11, Pp 109705- (2021)
Summary: Mouse embryonic stem cells (mESCs) can be maintained in vitro in defined N2B27 medium supplemented with two chemical inhibitors for GSK3 and MEK (2i) and the cytokine leukemia inhibitory factor (LIF), which act synergistically to promote sel
Externí odkaz:
https://doaj.org/article/12b1718d7710434e96efcd0a0b01bbc0
Autor:
Luis Zurkirchen, Sandra Varum, Sonja Giger, Annika Klug, Jessica Häusel, Raphaël Bossart, Martina Zemke, Claudio Cantù, Zeynep Kalender Atak, Nicola Zamboni, Konrad Basler, Lukas Sommer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The transcription factor Yin Yang 1 (YY1) plays an important role in human disease, yet little is known about its role in brain development. This study shows that YY1 controls cerebral cortex development by maintaining proliferation and survival of n
Externí odkaz:
https://doaj.org/article/bc26cd50490644df85c84964bd1b920a