Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Claudio A. Masuda"'
Autor:
Evandro A. De-Souza, Felipe S. A. Pimentel, Caio M. Machado, Larissa S. Martins, Wagner S. da-Silva, Mónica Montero-Lomelí, Claudio A. Masuda
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 1, Pp 55-61 (2014)
Classic galactosemia is a human autosomal recessive disorder caused by mutations in the GALT gene (GAL7 in yeast), which encodes the enzyme galactose-1-phosphate uridyltransferase. Here we show that the unfolded protein response pathway is triggered
Externí odkaz:
https://doaj.org/article/0d328464420d429e8395af3ccb6fae5a
Autor:
Sabrina Rita da Fonseca Rezende, Márcio Ribeiro Fontenele, Claudio Akio Masuda, Pedro a Lagerblad de Oliveira, Helena Maria Marcolla Araujo, Vânia Rita Elias Pinheiro Bittencourt, Milane de Souza Leite
Publikováno v:
Brazilian Journal of Veterinary Medicine, Vol 38, Iss Supl. 3, Pp 98-102 (2016)
[Receptores Toll-like em corpo gorduroso e glândula salivar do carrapato bovino Rhipicephalus microplus] Receptores Toll-like (TLRs) desempenham um importante papel no reconhecimento de componentes de agentes patogênicos e subsequente ativação da
Externí odkaz:
https://doaj.org/article/0f30ad2fbe034dc2a83246aba6aeef57
Autor:
Felipe S.A. Pimentel, Caio M. Machado, Evandro A. De-Souza, Caroline Mota Fernandes, Ana Luiza F.V. De-Queiroz, Guilherme F.S. Silva, Maurizio Del Poeta, Monica Montero-Lomeli, Claudio A. Masuda
Publikováno v:
Biochim Biophys Acta Mol Basis Dis
Classic galactosemia is an inborn error of metabolism caused by deleterious mutations on the GALT gene, which encodes the Leloir pathway enzyme galactose-1-phosphate uridyltransferase. Previous studies have shown that the endoplasmic reticulum unfold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b1d645b9eeb3f846ec457d33e2d50ce
https://europepmc.org/articles/PMC9326788/
https://europepmc.org/articles/PMC9326788/
Autor:
Joao Passos, James Chapman, Hanna Salmonowicz, Stella Victorelli, Helene Martini, Joel Riley, Catherine Cloix, Gerald Shadel, Jair Machado Espindola Netto, Diana Jurk, Anthony Lagnado, Lilian Gomez, Joshua Farr, Dominik Saul, Becca Reed, Laura Greaves, Derek Mann, Claudio Akio Masuda, Sundeep Khosla, Haiming Dai, Nathan LeBrasseur, Viktor Korolchuk, Xue Shae, Peter Adams, Stephen Tait, Maria Grazia Vizioli, Alva Sainz Castillo, Scott Kaufmann, Zhixun Dou
Senescent cells drive age-related tissue dysfunction partially via the induction of a chronic senescence-associated secretory phenotype (SASP). Mitochondria are major regulators of the SASP; however, the underlying mechanisms have not been elucidated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9bb90e82b7dfd7efa8a95281ed4df58
https://doi.org/10.21203/rs.3.rs-1247316/v1
https://doi.org/10.21203/rs.3.rs-1247316/v1
Autor:
Leena Habiballa, David Dolan, Anthony B. Lagnado, Madison L. Doolittle, Jodie Birch, Daniel Geh, Helen L. Reeves, Marie-Hélène Ruchaud-Sparagano, Shane A. Evans, Nicola Neretti, Amy L Collins, Sushma Nagaraja Grellscheid, João F. Passos, Derek A. Mann, Thomas von Zglinicki, Sanjay Pandanaboyana, Colin H Wilson, Claudio Akio Masuda, Diana Jurk, Caroline L. Wilson, Tamar Tchkonia, Adam Hruby, Suchira Gallage, Maria Grazia Vizioli, Stella Victorelli, Petra Hirsova, Jack Leslie, Kevin D. Pavelko, Hanna Salmonowicz, Mathias Heikenwalder, Gabriele Saretzki, James Chapman, Sundeep Khosla, Mikolaj Ogrodnik, Bernadette Carroll, James L. Kirkland, Fiona Oakley
Publikováno v:
The EMBO Journal
e106048
The EMBO Journal, 2021, Vol.40(9), pp.e106048 [Peer Reviewed Journal]
EMBO Journal
Lagnado, A, Carroll, B, Passos, J F & al., E 2021, ' Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner ', EMBO Journal, vol. 40, no. 9, e106048 . https://doi.org/10.15252/embj.2020106048
e106048
The EMBO Journal, 2021, Vol.40(9), pp.e106048 [Peer Reviewed Journal]
EMBO Journal
Lagnado, A, Carroll, B, Passos, J F & al., E 2021, ' Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner ', EMBO Journal, vol. 40, no. 9, e106048 . https://doi.org/10.15252/embj.2020106048
Cellular senescence is characterized by an irreversible cell cycle arrest as well as a pro-inflammatory phenotype, thought to contribute to aging and age-related diseases. Neutrophils have essential roles in inflammatory responses; however, in certai
Autor:
Claudio A. Masuda, Silas Pinto, Antonio Galina, Henrique Camara, Ana Luiza F. V. De-Queiroz, Caio M. Machado, Marcelo A. Mori, Mikaella L. Felix-Formiga, Felipe S. A. Pimentel, Evandro A. De-Souza, Mónica Montero-Lomelí
Publikováno v:
J Biol Chem
In the presence of galactose, lithium ions activate the unfolded protein response (UPR) by inhibiting phosphoglucomutase activity and causing the accumulation of galactose-related metabolites, including galactose-1-phosphate. These metabolites also a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c76e9bba63242f42c098006e521fce8
https://europepmc.org/articles/PMC7086034/
https://europepmc.org/articles/PMC7086034/
Autor:
Caroline Mota Fernandes, Deveney Dasilva, Maurizio Del Poeta, Claudio A. Masuda, Gabriel S. Matos, Mónica Montero-Lomelí, Juliana B. Madeira
Publikováno v:
Biochim Biophys Acta Mol Cell Biol Lipids
SBF (Swi4/Swi6 Binding Factor) complex is a crucial regulator of G1/S transition in Saccharomyces cerevisiae. Here, we show that SBF complex is required for myriocin resistance, an inhibitor of sphingolipid synthesis. This phenotype was not shared wi
Autor:
Laryssa S Messias, Bruno L. Bozaquel-Morais, Gabriel S. Matos, Claudio A. Masuda, Juliana B. Madeira, Mónica Montero-Lomelí
Publikováno v:
FEMS yeast research. 19(3)
In this study, we found that cell cycle arrest induced by alpha-factor mating pheromone (G1), hydroxyurea (S) or nocodazole (G2/M) was associated to increased lipid droplet (LD) content. To identify novel cell cycle genes involved in LD homeostasis,
Autor:
Rodrigo D. Requião, Fernando L. Palhano, Silvana Rossetto, Claudio A. Masuda, Géssica C. Barros, Rodolfo L. Carneiro, Tatiana Domitrovic, Mariana H. Moreira
Publikováno v:
Journal of Biological Chemistry. 296:100586
Highly positively charged protein segments are known to result in poor translation efficiency. This effect is explained by ribosome stalling caused by electrostatic interactions between the nascent peptide and the negatively charged ribosome exit tun
Autor:
Katia C. Gondim, David Majerowicz, Hans Kristian Hannibal-Bach, Luciano Aparecido Meireles Grillo, Claudio A. Masuda, Nils J. Færgeman, Michele Alves-Bezerra, Bruno L. Bozaquel-Morais, Jens Knudsen, Rodolfo S C Castro
Publikováno v:
Majerowicz, D, Hannibal-Bach, H K, Castro, R S C, Bozaquel-Morais, B L, Alves-Bezerra, M, Grillo, L A M, Masuda, C A, Færgeman, N J, Knudsen, J & Gondim, K C 2016, ' The ACBP gene family in Rhodnius prolixus : Expression, characterization and function of RpACBP-1 ', Insect Biochemistry and Molecular Biology, vol. 72, pp. 41-52 . https://doi.org/10.1016/j.ibmb.2016.03.002
The acyl-CoA-binding proteins (ACBP) constitute a family of conserved proteins that bind acyl-CoA with high affinity and protect it from hydrolysis. Thus, ACBPs may have essential roles in basal cellular lipid metabolism. The genome of the insect Rho