Zobrazeno 1 - 10
of 1 001
pro vyhledávání: '"Claudio Franceschi"'
Autor:
Shelia Govind, Pierre Olivier Lang, Alexander Bürkle, María Moreno-Villanueva, Claudio Franceschi, Miriam Capri, Jurgen Bernard, Birgit Weinberger, Beatrix Grubeck-Loebenstein, Simone Fiegl, Efstathios S. Gonos, Ewa Sikora, Eugène Jansen, Martijn E. T. Dollé, Tilman Grune, Nicolle Breusing, Richard Aspinall
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-12 (2024)
Abstract Decline in immune function with age has been studied extensively, but approaches to immune restoration have been hampered by the lack of simple methods of identifying individuals whose immune system is in decline. Our approach has been to id
Externí odkaz:
https://doaj.org/article/312250a0783f4d4ab133860b37146370
Autor:
Jenny Hällqvist, Michael Bartl, Mohammed Dakna, Sebastian Schade, Paolo Garagnani, Maria-Giulia Bacalini, Chiara Pirazzini, Kailash Bhatia, Sebastian Schreglmann, Mary Xylaki, Sandrina Weber, Marielle Ernst, Maria-Lucia Muntean, Friederike Sixel-Döring, Claudio Franceschi, Ivan Doykov, Justyna Śpiewak, Héloїse Vinette, Claudia Trenkwalder, Wendy E. Heywood, Kevin Mills, Brit Mollenhauer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Parkinson’s disease is increasingly prevalent. It progresses from the pre-motor stage (characterised by non-motor symptoms like REM sleep behaviour disorder), to the disabling motor stage. We need objective biomarkers for early/pre-motor d
Externí odkaz:
https://doaj.org/article/c9c6caebce4b4ef39c0513634c446a29
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/bd5cac9eb81a473aa2823686df09f1d6
Autor:
Vanessa Schoissengeier, Lina Maqboul, Daniela Weber, Tilman Grune, Alexander Bürkle, Maria Moreno-Villaneuva, Claudio Franceschi, Miriam Capri, Jürgen Bernhard, Olivier Toussaint, Florence Debacq-Chainiaux, Birgit Weinberger, Efstathios S. Gonos, Ewa Sikora, Martijn Dollé, Eugène Jansen, P. Eline Slagboom, Antti Hervonnen, Mikko Hurme, Nicolle Breusing, Jan Frank, Andrew C. Bulmer, Karl-Heinz Wagner
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110234- (2024)
Summary: Recent studies have shown that elevated concentrations of unconjugated bilirubin (UCB) may be a protective host factor against the development of noncommunicable diseases (NCDs), whereas low levels of UCB are associated with the opposite eff
Externí odkaz:
https://doaj.org/article/c552b2d7871143dc8639d53d930fb083
Autor:
Camilla Pellegrini, Francesco Ravaioli, Sara De Fanti, Chiara Pirazzini, Chiara D’Silva, Paolo Garagnani, Claudio Franceschi, Francesca Bonifazi, Pier Luigi Zinzani, Massimiliano Bonafè, Maria Guarino, Raffaele Lodi, Pietro Cortelli, Caterina Tonon, Micaela Mitolo, Luisa Sambati, Luca Morandi, Maria Giulia Bacalini
Publikováno v:
Diagnostics, Vol 14, Iss 22, p 2541 (2024)
Background: Neuronal loss is a major pathological feature of neurodegenerative diseases. The analysis of plasma cell-free DNA (cfDNA) is an emerging approach to track cell death events in a minimally invasive way and from inaccessible areas of the bo
Externí odkaz:
https://doaj.org/article/25944fbd9dd8468983d623d1178b0e57
Autor:
Alena Kalyakulina, Igor Yusipov, Elena Kondakova, Maria Giulia Bacalini, Cristina Giuliani, Tatiana Sivtseva, Sergey Semenov, Artem Ksenofontov, Maria Nikolaeva, Elza Khusnutdinova, Raisa Zakharova, Maria Vedunova, Claudio Franceschi, Mikhail Ivanchenko
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-19 (2023)
Abstract Background Yakuts are one of the indigenous populations of the subarctic and arctic territories of Siberia characterized by a continental subarctic climate with severe winters, with the regular January average temperature in the regional cap
Externí odkaz:
https://doaj.org/article/d7bdc5105f5b422eabfe9db5c62bca9a
Autor:
Claudia Sala, Pietro Di Lena, Danielle Fernandes Durso, Italo Faria do Valle, Maria Giulia Bacalini, Daniele Dall’Olio, Claudio Franceschi, Gastone Castellani, Paolo Garagnani, Christine Nardini
Publikováno v:
Frontiers in Bioinformatics, Vol 4 (2024)
Introduction: DNA methylation clocks presents advantageous characteristics with respect to the ambitious goal of identifying very early markers of disease, based on the concept that accelerated ageing is a reliable predictor in this sense.Methods: Su
Externí odkaz:
https://doaj.org/article/0534b04076454726877ae0d8a3254bb8
Autor:
Danay Saavedra, Ana Laura Añé-Kourí, Nir Barzilai, Calogero Caruso, Kyung-Hyun Cho, Luigi Fontana, Claudio Franceschi, Daniela Frasca, Nuris Ledón, Laura J. Niedernhofer, Karla Pereira, Paul D. Robbins, Alexa Silva, Gisela M. Suarez, Wim Vanden Berghe, Thomas von Zglinicki, Graham Pawelec, Agustín Lage
Publikováno v:
Immunity & Ageing, Vol 20, Iss 1, Pp 1-10 (2023)
Abstract Aging is a gradual, continuous series of natural changes in biological, physiological, immunological, environmental, psychological, behavioral, and social processes. Aging entails changes in the immune system characterized by a decrease in t
Externí odkaz:
https://doaj.org/article/4c145aa2e8744ecfa51288f777b2ec7a
Autor:
Jessica Perugini, Arianna Smorlesi, Samantha Acciarini, Eleonora Mondini, Georgia Colleluori, Chiara Pirazzini, Katarzyna Malgorzata Kwiatkowska, Paolo Garagnani, Claudio Franceschi, Maria Cristina Zingaretti, Christian Dani, Antonio Giordano, Saverio Cinti
Publikováno v:
Cells, Vol 13, Iss 11, p 943 (2024)
Subcutaneous adipocytes are crucial for mammary gland epithelial development during pregnancy. Our and others’ previous data have suggested that adipo-epithelial transdifferentiation could play a key role in the mammary gland alveolar development.
Externí odkaz:
https://doaj.org/article/3544c7d4a0f34860a5c9acc81f71cdbb
Autor:
Luca Baldelli, Chiara Pirazzini, Luisa Sambati, Francesco Ravaioli, Davide Gentilini, Giovanna Calandra-Buonaura, Pietro Guaraldi, Claudio Franceschi, Pietro Cortelli, Paolo Garagnani, Maria Giulia Bacalini, Federica Provini
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-4 (2023)
Abstract Isolated REM Sleep Behavior Disorder (iRBD) is the strongest prodromal marker for α-synucleinopathies. Overt α-synucleinopathies and aging share several mechanisms, but this relationship has been poorly investigated in prodromal phases. Us
Externí odkaz:
https://doaj.org/article/6e884a80cc894b9782345da85797f7bd