Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Claudio, Valenzuela"'
Autor:
Ricardo Huilcaman, Natalia Veliz-Olivos, Whitney Venturini, Alexandra Olate-Briones, Adriana V. Treuer, Claudio Valenzuela, Nelson Brown, Rodrigo Moore-Carrasco
Publikováno v:
Platelets, Vol 32, Iss 8, Pp 1113-1119 (2021)
Cardiovascular diseases (CVDs) remain leading causes of death worldwide. While platelet-mediated thrombus formation following the rupture of an atherosclerotic plaque is one of the key pathophysiologic events in CVDs, the role of platelets in previou
Externí odkaz:
https://doaj.org/article/bae285f9acae40369ee07ccffe52ca30
Autor:
Oscar Forero-Doria, Luis Guzmán, Felipe Jiménez-Aspee, Javier Echeverría, Sergio Wehinger, Claudio Valenzuela, Ramiro Araya-Maturana, Maximiliano Martínez-Cifuentes
Publikováno v:
Antioxidants, Vol 11, Iss 6, p 1104 (2022)
In this work, we report the synthesis of curcuminoids with ionic liquid characteristics, obtained by incorporating alkyl-substituted pyridinium moiety rather than one phenyl group through a two-step process. The antioxidant capacity of the obtained c
Externí odkaz:
https://doaj.org/article/7aa009af74754b1cacd2c7c9ebdc9a8f
Autor:
Ricardo Huilcaman, Whitney Venturini, Lucia Fuenzalida, Angel Cayo, Raul Segovia, Claudio Valenzuela, Nelson Brown, Rodrigo Moore-Carrasco
Publikováno v:
Cells, Vol 11, Iss 6, p 1014 (2022)
Platelets play important roles in thrombosis-dependent obstructive cardiovascular diseases. In addition, it has now become evident that platelets also participate in the earliest stages of atherosclerosis, including the genesis of the atherosclerotic
Externí odkaz:
https://doaj.org/article/a16ea4e00a6a473aa1ed0acdbb11c5d6
Autor:
Bárbara Arévalo, Verónica García-Castillo, Carlos Pérez-Plasencia, Margarita Gutiérrez, Rebeca Salgado-García, Nelson E. Brown, Alexandra Olate-Briones, Francisco Valdes, Claudio Valenzuela, Angel Cayo
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 22:1414-1425
Background: Adenosine is a natural nucleoside present in a variety of organs and tissues, where it acts as a modulator of diverse physiological and pathophysiological processes. These actions are mediated by at least four G protein-coupled receptors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::630fad045cd1685806fc4e79944f09ac
https://doi.org/10.2174/1871520621666210528151818
https://doi.org/10.2174/1871520621666210528151818
Autor:
Amelia Cox, Rocío González-Parada, José Coche, Gabriela Carrasco, Hugo González, Macarena Gajardo, Camilo Berríos, Antonia Ramos, Patricio Arros, Jorge Vielma, Ian Pérez, Claudio Valenzuela, Julieta Orlando, Andrés E. Marcoleta, Francisco P. Chávez
Tan Tári Bricks is this year's iDL Chilean Team. We propose a platform based on synthetic and computational biology to evaluate the risk of Antarctic beta-lactamases for developing inhibitory proteins. By focusing on three key areas: a new scientifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a847503594deed942ce0fa0932b563
Autor:
Adriana V. Treuer, Whitney Venturini, Rodrigo Moore-Carrasco, Nelson E. Brown, Alexandra Olate-Briones, Claudio Valenzuela, Ricardo Huilcaman, Natalia Veliz-Olivos
Publikováno v:
Platelets. 32:1113-1119
Cardiovascular diseases (CVDs) remain leading causes of death worldwide. While platelet-mediated thrombus formation following the rupture of an atherosclerotic plaque is one of the key pathophysiologic events in CVDs, the role of platelets in previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d461836d2e7eb6107afea50e1f4be96
https://doi.org/10.1080/09537104.2021.1902970
https://doi.org/10.1080/09537104.2021.1902970
Autor:
Angel Cayo, Whitney Venturini, Danitza Rebolledo-Mira, Rodrigo Moore-Carrasco, Andrés A. Herrada, Estefanía Nova-Lamperti, Claudio Valenzuela, Nelson E. Brown
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9284
Despite not dividing, senescent cells acquire the ability to synthesize and secrete a plethora of bioactive molecules, a feature known as the senescence-associated secretory phenotype (SASP). In addition, senescent cells often upregulate autophagy, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120801459f3437679e73f7b0a23e603d
https://doi.org/10.3390/ijms24119284
https://doi.org/10.3390/ijms24119284
Autor:
Iván Palomo, Claudio Valenzuela, Margarita Gutiérrez, Luis Astudillo, Marcelo Alarcón, Eduardo Fuentes
Publikováno v:
Molecules, Vol 18, Iss 7, Pp 8120-8135 (2013)
In the past 30 years, only three natural products have been sources of new drugs with antiplatelet activity. In this study, we have demonstrated for the first time that guanosine from Solanum lycopersicum possesses antiplatelet (secretion, spreading,
Externí odkaz:
https://doaj.org/article/738962b382c542008461eb28a165dc68
Autor:
Francisco, Valdés, Bárbara, Arévalo, Margarita, Gutiérrez, Verónica, García-Castillo, Rebeca, Salgado-García, Carlos, Pérez-Plasencia, Claudio, Valenzuela, Ángel, Cayo, Alexandra, Olate-Briones, Nelson, Brown
Publikováno v:
Anti-cancer agents in medicinal chemistry. 22(7)
Adenosine is a natural nucleoside present in a variety of organs and tissues, where it acts as a modulator of diverse physiological and pathophysiological processes. These actions are mediated by at least four G protein-coupled receptors, which are w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b00f5e4cbef03afacb213c3ff8fa60d
https://pubmed.ncbi.nlm.nih.gov/34053425
https://pubmed.ncbi.nlm.nih.gov/34053425
Autor:
Daniel Mancilla, Claudio Valenzuela, Diego Méndez, Raul Segovia, Rodrigo Moore-Carrasco, Whitney Venturini, Angel Cayo, Eduardo Fuentes, Alexandra Olate-Briones, Nelson E. Brown
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 9
International Journal of Molecular Sciences, Vol 21, Iss 3287, p 3287 (2020)
Volume 21
Issue 9
International Journal of Molecular Sciences, Vol 21, Iss 3287, p 3287 (2020)
Aging is one of the main risk factors for the development of chronic diseases, with both the vascular endothelium and platelets becoming functionally altered. Cellular senescence is a form of permanent cell cycle arrest initially described in primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490ad8e3129d70c92a48eb1f30dcfa00
http://europepmc.org/articles/PMC7246568
http://europepmc.org/articles/PMC7246568