Zobrazeno 1 - 10
of 521
pro vyhledávání: '"Claudio, Tripodo"'
Autor:
Adriana Rosa Gambardella, Caterina Antonucci, Cristiana Zanetti, Francesco Noto, Sara Andreone, Davide Vacca, Valentina Pellerito, Chiara Sicignano, Giuseppe Parrottino, Valentina Tirelli, Antonella Tinari, Mario Falchi, Adele De Ninno, Luca Businaro, Stefania Loffredo, Gilda Varricchi, Claudio Tripodo, Claudia Afferni, Isabella Parolini, Fabrizio Mattei, Giovanna Schiavoni
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-25 (2024)
Abstract Immune cell-derived extracellular vesicles (EV) affect tumor progression and hold promise for therapeutic applications. Eosinophils are major effectors in Th2-related pathologies recently implied in cancer. Here, we evaluated the anti-tumor
Externí odkaz:
https://doaj.org/article/9b0f9646ff2d4fdcab61db2ede19e22c
Autor:
Xinyi Zhang, Saradha Venkatachalapathy, Daniel Paysan, Paulina Schaerer, Claudio Tripodo, Caroline Uhler, G. V. Shivashankar
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Ductal carcinoma in situ (DCIS) is a pre-invasive tumor that can progress to invasive breast cancer, a leading cause of cancer death. We generate a large-scale tissue microarray dataset of chromatin images, from 560 samples from 122 female p
Externí odkaz:
https://doaj.org/article/7d7644fe553d46ba91722e856b0dcf58
Autor:
Min Liu, Giorgio Bertolazzi, Shruti Sridhar, Rui Xue Lee, Patrick Jaynes, Kevin Mulder, Nicholas Syn, Michal Marek Hoppe, Shuangyi Fan, Yanfen Peng, Jocelyn Thng, Reiya Chua, Jayalakshmi, Yogeshini Batumalai, Sanjay De Mel, Limei Poon, Esther Hian Li Chan, Joanne Lee, Susan Swee-Shan Hue, Sheng-Tsung Chang, Shih-Sung Chuang, K. George Chandy, Xiaofei Ye, Qiang Pan-Hammarström, Florent Ginhoux, Yen Lin Chee, Siok-Bian Ng, Claudio Tripodo, Anand D. Jeyasekharan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Macrophages are abundant immune cells in the microenvironment of diffuse large B-cell lymphoma (DLBCL). Macrophage estimation by immunohistochemistry shows varying prognostic significance across studies in DLBCL, and does not provide a compr
Externí odkaz:
https://doaj.org/article/dcc5aed0ca7744c29e4e5d657125614a
Autor:
Francesco Farris, Alice Elhagh, Ilaria Vigorito, Nicoletta Alongi, Federica Pisati, Michele Giannattasio, Francesca Casagrande, Lisa Veghini, Vincenzo Corbo, Claudio Tripodo, Arianna Di Napoli, Vittoria Matafora, Angela Bachi
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The tumor microenvironment is a complex ecosystem that plays a critical role in cancer progression and treatment response. Recently, extracellular amyloid fibrils have emerged as novel components of the tumor microenvironment; however, their
Externí odkaz:
https://doaj.org/article/03990e386b40410eab28aabc219a347f
Autor:
Ambra Cappelletto, Edoardo Alfì, Nina Volf, Thi Van Anh Vu, Francesca Bortolotti, Giulio Ciucci, Simone Vodret, Marco Fantuz, Martina Perin, Andrea Colliva, Giacomo Rozzi, Matilde Rossi, Giulia Ruozi, Lorena Zentilin, Roman Vuerich, Daniele Borin, Romano Lapasin, Silvano Piazza, Mattia Chiesa, Daniela Lorizio, Luca Triboli, Sandeep Kumar, Gaia Morello, Claudio Tripodo, Maurizio Pinamonti, Giulia Maria Piperno, Federica Benvenuti, Alessandra Rustighi, Hanjoong Jo, Stefano Piccolo, Giannino Del Sal, Alessandro Carrer, Mauro Giacca, Serena Zacchigna
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-14 (2024)
Abstract Background New drugs to tackle the next pathway or mutation fueling cancer are constantly proposed, but 97% of them are doomed to fail in clinical trials, largely because they are identified by cellular or in silico screens that cannot predi
Externí odkaz:
https://doaj.org/article/a789156b8a0b44008d091dcfb970d332
Autor:
Emilio Iannitto, Simone Ferrero, Côme Bommier, Daniela Drandi, Martina Ferrante, Krimo Bouabdallah, Sylvain Carras, Guido Gini, Vincent Camus, Salvatrice Mancuso, Luigi Marcheselli, Angela Ferrari, Michele Merli, Benoit Tessoulin, Caterina Stelitano, Kheira Beldjord, Giovanni Roti, Fabrice Jardin, Barbara Castagnari, Francesca Palombi, Lucile Baseggio, Alexandra Traverse-Glehen, Claudio Tripodo, Anna Marina Liberati, Margherita Parolini, Sara Usai, Caterina Patti, Massimo Federico, Maurizio Musso, Marco Ladetto, Emanuele Zucca, Catherine Thieblemont
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/5f4a0e9b701e495c958e1cf920f2724a
Autor:
Francesca Di Modugno, Anna Di Carlo, Sheila Spada, Belinda Palermo, Lorenzo D'Ambrosio, Daniel D'Andrea, Gaia Morello, Beatrice Belmonte, Isabella Sperduti, Vittoria Balzano, Enzo Gallo, Roberta Melchionna, Mariangela Panetta, Giulia Campo, Francesca De Nicola, Frauke Goeman, Barbara Antoniani, Silvia Carpano, Gianmaria Frigè, Sarah Warren, Filippo Gallina, Diether Lambrechts, Jieyi Xiong, Benjamin G. Vincent, Nathan Wheeler, Dante S. Bortone, Federico Cappuzzo, Francesco Facciolo, Claudio Tripodo, Paolo Visca, Paola Nisticò
Publikováno v:
EBioMedicine, Vol 101, Iss , Pp 105003- (2024)
Summary: Background: Tertiary Lymphoid Structures (TLS) correlate with positive outcomes in patients with NSCLC and the efficacy of immune checkpoint blockade (ICB) in cancer. The actin regulatory protein hMENA undergoes tissue-specific splicing, pro
Externí odkaz:
https://doaj.org/article/5fd739eb5c1748ce8a0ed4de3fe1985a
Autor:
Camilla Tombari, Alessandro Zannini, Rebecca Bertolio, Silvia Pedretti, Matteo Audano, Luca Triboli, Valeria Cancila, Davide Vacca, Manuel Caputo, Sara Donzelli, Ilenia Segatto, Simone Vodret, Silvano Piazza, Alessandra Rustighi, Fiamma Mantovani, Barbara Belletti, Gustavo Baldassarre, Giovanni Blandino, Claudio Tripodo, Silvio Bicciato, Nico Mitro, Giannino Del Sal
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Reprogramming of amino acid metabolism, sustained by oncogenic signaling, is crucial for cancer cell survival under nutrient limitation. Here we discovered that missense mutant p53 oncoproteins stimulate de novo serine/glycine synthesis and
Externí odkaz:
https://doaj.org/article/ed8691094df743f6a79d37fb5d803a8a
Autor:
Caterina Cascini, Chiara Ratti, Laura Botti, Beatrice Parma, Valeria Cancila, Adriana Salvaggio, Cristina Meazza, Claudio Tripodo, Mario P. Colombo, Claudia Chiodoni
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-16 (2023)
Abstract Background Osteosarcoma (OS) is the most common primary bone tumor in children and adolescent. Surgery and multidrug chemotherapy are the standard of treatment achieving 60–70% of event-free survival for localized disease at diagnosis. How
Externí odkaz:
https://doaj.org/article/16a61672cdc9484e8c7941b0401dc75c
Autor:
Barbara Bassani, Giorgia Simonetti, Valeria Cancila, Antonio Fiorino, Marilena Ciciarello, Annamaria Piva, Arman Mandegar Khorasani, Claudia Chiodoni, Daniele Lecis, Alessandro Gulino, Eugenio Fonzi, Laura Botti, Paola Portararo, Massimo Costanza, Marta Brambilla, Giorgia Colombo, Juerg Schwaller, Alexandar Tzankov, Maurilio Ponzoni, Fabio Ciceri, Niccolò Bolli, Antonio Curti, Claudio Tripodo, Mario P. Colombo, Sabina Sangaletti
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113794- (2024)
Summary: Acute myeloid leukemia (AML) progression is influenced by immune suppression induced by leukemia cells. ZEB1, a critical transcription factor in epithelial-to-mesenchymal transition, demonstrates immune regulatory functions in AML. Silencing
Externí odkaz:
https://doaj.org/article/da7ae959a4304ef9b858b1b572ed0a44