Preclinical modeling of metabolic syndrome to study the pleiotropic effects of novel antidiabetic therapy independent of obesity

Autor: Jonathan P. Mochel, Jessica L. Ward, Thomas Blondel, Debosmita Kundu, Maria M. Merodio, Claudine Zemirline, Emilie Guillot, Ryland T. Giebelhaus, Paulina de la Mata, Chelsea A. Iennarella-Servantez, April Blong, Seo Lin Nam, James J. Harynuk, Jan Suchodolski, Asta Tvarijonaviciute, José Joaquín Cerón, Agnes Bourgois-Mochel, Faiez Zannad, Naveed Sattar, Karin Allenspach

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)

Abstract Cardiovascular-kidney-metabolic health reflects the interactions between metabolic risk factors, chronic kidney disease, and the cardiovascular system. A growing body of literature suggests that metabolic syndrome (MetS) in individuals of no

Externí odkaz: https://doaj.org/article/d64609278e0c44a5a0b47e66b29defbd

Performance and Tolerance of a Protocol for Idiopathic Chronic Greasy Seborrhea in 18 Dogs Using a Shampoo and Mousse Containing Plant Extracts

Autor: Jevgenija Kondratjeva, Jessie Brun, Nicolas Amalric, Fabien Moog, Daniel Combarros, Charline Pressanti, Claudine Zemirline, Nadège Maubert, Elodie Ollivier, Marina Gatellet, Marie Christine Cadiergues

Publikováno v: Veterinary Sciences, Vol 10, Iss 2, p 95 (2023)

The study aimed to evaluate the tolerance, performance and effect on hair lipids and skin hydration of a protocol combining applications of one shampoo and subsequent mousses containing plant extracts (Ophytrium and Seboliance) in dogs with an undiag

Externí odkaz: https://doaj.org/article/0e81b174bc38410cb58c067325479ca7

Dynamic interactions between cephalexin and macrophages on different Staphylococcus aureus inoculum sizes: a tripartite in vitro model

Autor: Claudine Zemirline, Séverine Boullier, Aude A. Ferran, Alain Bousquet-Mélou, Pierre-Louis Toutain, Elodie Lallemand

Publikováno v: BMC Veterinary Research, Vol 17, Iss 1, Pp 1-10 (2021)
BMC Veterinary Research
BMC Veterinary Research, BioMed Central, 2021, 17 (1), ⟨10.1186/s12917-021-02746-8⟩

Background The bactericidal activity of an antimicrobial drug is generally assessed by in vitro bacterial time-kill experiments which do not include any components of the immune system, even though the innate immunity, the primary host defence, is pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9262106545e01e2f2bb0519b71e34d40
https://doaj.org/article/7e2bc957757248328addf4ee43574941

SGLT2 Inhibitors and Potential Applications in Treating Metabolic Syndrome

Autor: Clayton Goddard, Karin Allenspach, Audrey Deflandre, Claudine Zemirline, Emilie Guillot, Jonathan P. Mochel

SGLT2 inhibitors act to induce glucosuria and have been shown to be efficacious in the treatment of type II diabetes mellitus but have also been shown to positively affect cardiovascular conditions and some benefitting kidney function. SGLT2i have sh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef684c71eca4c086c134ddce5301f035
https://doi.org/10.20944/preprints202204.0202.v1

Performance of Daily Pads Containing Ophytrium and Chlorhexidine Digluconate 3% in Dogs With Local Cutaneous Bacterial and/or

Autor: Marina, Gatellet, Roxane, Kesteman, Benjamin, Baulez, Félix, Pradiès, Pierre-Marie, Cadot, Hélène, Dropsy, Pierre, Fiora, Jean-Loup, Mathet, Elodie, Ollivier, Charlotte, Billy, Claudine, Zemirline, Xavier, De Jaeger

Publikováno v: Frontiers in Veterinary Science

Local disturbances of the microbiota are common in dogs with underlying skin conditions. Antiseptic topical products are indicated to control such superficial disorders. The objective of this study was to evaluate the performance of a daily applicati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dce6a8060002429afd3ae525125f9942
https://pubmed.ncbi.nlm.nih.gov/34026882