Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Claudine Guilbault"'
Autor:
Claude Lachance, Gabriella Wojewodka, Tom A A Skinner, Claudine Guilbault, Juan B De Sanctis, Danuta Radzioch
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74875 (2013)
We previously identified Fragile X-related protein 1 (FXR1) as an RNA-binding protein involved in the post-transcriptional control of TNF and other cytokines in macrophages. Macrophages derived from FXR1-KO mice overexpress several inflammatory cytok
Externí odkaz:
https://doaj.org/article/3dcb8abab53a45ea8b6d179c7f5c9337
Autor:
Elias Matouk, Marian Hajduch, Zienab Saeed, Gabriella Wojewodka, Claudine Guilbault, Danuta Radzioch, Juan B. De Sanctis
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 41:100-106
Patients with cystic fibrosis (CF) and Cftr-knockout mice (CF mice) display an imbalance in fatty acids, with high arachidonic acid (AA) and low docosahexaenoic acid (DHA) concentrations. Our recent studies demonstrated defects in another class of li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed6db7c90384d5c4eaa8405151feb92a
https://doi.org/10.1165/rcmb.2008-0279oc
https://doi.org/10.1165/rcmb.2008-0279oc
Autor:
Claudine Guilbault, Danuta Radzioch, Juan B. De Sanctis, René St-Arnaud, Dominique Marion, Jennifer Henri, Zienab Saeed
Publikováno v:
Journal of Cystic Fibrosis. 7:222-230
Background The most recently described phenotype associated with Cystic Fibrosis (CF) is reduced bone mineral density which results in osteopenia and osteoporosis. The etiology of the early onset of osteoporosis in CF patients has remained to be esta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019a3f5aef81b147a06043be2e7253f1
https://doi.org/10.1016/j.jcf.2007.09.001
https://doi.org/10.1016/j.jcf.2007.09.001
Autor:
Thomas A. A. Skinner, Danuta Radzioch, Claudine Guilbault, Zienab Saeed, Stan Kubow, Juan B. De Sanctis, Elias Matouk, Gabriella Wojewodka, Marian Hajduch, Larry C. Lands, Regina Maria Vilela, Claude Lachance
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 38:47-56
Chronic and persistent lung infections cause the majority of morbidity and mortality in patients with cystic fibrosis (CF). Galactosyl ceramide has been previously shown to be involved in Pseudomonas internalization. Therefore, we assessed ceramide l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb2e65a6d723a24350a8bbcef9cf05e
https://doi.org/10.1165/rcmb.2007-0036oc
https://doi.org/10.1165/rcmb.2007-0036oc
Publikováno v:
Current Pharmaceutical Design. 13:3252-3263
Before the cloning of the CFTR gene in 1989, there were relatively few treatment options for the many phenotypes associated with cystic fibrosis (CF). The advancement of research in areas such as immunology, molecular biology and pharmacology have pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff3cd707a01060541ef0809fedbc93e0
https://doi.org/10.2174/138161207782341268
https://doi.org/10.2174/138161207782341268
Autor:
Danuta Radzioch, Claude Lachance, Peter K. Stotland, Claudine Guilbault, Thomas A. Hamilton, David H. Eidelman, Mifong Tam, Anna Keller, Mary M. Stevenson, Elizabeth A. Cowley, Luann Thompson-Snipes
Publikováno v:
Immunology. 107:297-305
Cystic fibrosis females have a worse prognosis compared to male patients. Furthermore, cystic fibrosis patients infected with Pseudomonas aeruginosa have been shown to have dysregulated cytokine profiles, as higher levels of tumour necrosis factor al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2427511e9e60811f2e0f244316a8f4e4
https://doi.org/10.1046/j.1365-2567.2002.01508.x
https://doi.org/10.1046/j.1365-2567.2002.01508.x
Autor:
Tom A. A. Skinner, Claude Lachance, Gabriella Wojewodka, Danuta Radzioch, Juan B. De Sanctis, Claudine Guilbault
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74875 (2013)
PLoS ONE
PLoS ONE
We previously identified Fragile X-related protein 1 (FXR1) as an RNA-binding protein involved in the post-transcriptional control of TNF and other cytokines in macrophages. Macrophages derived from FXR1-KO mice overexpress several inflammatory cytok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3470a4367dcdcb8fafae608a773068be
http://europepmc.org/articles/PMC3771966?pdf=render
http://europepmc.org/articles/PMC3771966?pdf=render
Publikováno v:
American journal of respiratory cell and molecular biology. 36(1)
Animal models of cystic fibrosis (CF) are powerful tools that enable the study of the mechanisms and complexities of human disease. Murine models have several intrinsic advantages compared with other animal models, including lower cost, maintenance,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e178ebbaecbba0ea470d326b7c23639
https://pubmed.ncbi.nlm.nih.gov/16888286
https://pubmed.ncbi.nlm.nih.gov/16888286
Autor:
Jaroslav P. Novak, Marie-Christine Guiot, Marie-Linda Boghdady, Thomas J. Hudson, Danuta Radzioch, Zienab Saeed, Claudine Guilbault, Patricia Martin
Publikováno v:
Physiological genomics. 25(2)
Cystic fibrosis (CF) is caused by a defect in the CF transmembrane conductance regulator (CFTR) protein that functions as a chloride channel. Dysfunction of the CFTR protein results in salty sweat, pancreatic insufficiency, intestinal obstruction, ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e58860746f355d4cb40ebee5c9324d
https://pubmed.ncbi.nlm.nih.gov/16418321
https://pubmed.ncbi.nlm.nih.gov/16418321
Autor:
M. L. Boghdady, Danuta Radzioch, Houle D, Marie-Christine Guiot, D. Marion, Claudine Guilbault, P. Martin
Publikováno v:
Laboratory animals. 39(3)
To better understand the mechanism of lung infection with Pseudomonas aeruginosa ( P. aeruginosa), many techniques have been developed in order to establish lung infection in rodents. A model of chronic lung infection, using tracheotomy to inoculate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afd55a850487e43c1cb5b3e58a167116
https://pubmed.ncbi.nlm.nih.gov/16004694
https://pubmed.ncbi.nlm.nih.gov/16004694