Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Claudine Gaudon"'
Autor:
Zaineb Fourati, Olga Kolesnikova, Régis Back, Jenny Keller, Clément Charenton, Valerio Taverniti, Claudine Gaudon Plesse, Noureddine Lazar, Dominique Durand, Herman van Tilbeurgh, Bertrand Séraphin, Marc Graille
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e96828 (2014)
Eukaryotic mRNA decay is a highly regulated process allowing cells to rapidly modulate protein production in response to internal and environmental cues. Mature translatable eukaryotic mRNAs are protected from fast and uncontrolled degradation in the
Externí odkaz:
https://doaj.org/article/f165439262694d659bf245355ce86fcd
Autor:
Loreline Cosson, Bertrand Séraphin, Clément Charenton, Claudine Gaudon-Plesse, Nathalie Ulryck, Régis Back, Marc Graille
Publikováno v:
'Nucleic Acids Research ', vol: 48, pages: 6353-6366 (2020)
Nucleic Acids Research
Nucleic Acids Research, 2020, 48 (11), ⟨10.1093/nar/gkaa337⟩
Nucleic Acids Research, Oxford University Press, 2020, 48 (11), ⟨10.1093/nar/gkaa337⟩
Nucleic Acids Research
Nucleic Acids Research, 2020, 48 (11), ⟨10.1093/nar/gkaa337⟩
Nucleic Acids Research, Oxford University Press, 2020, 48 (11), ⟨10.1093/nar/gkaa337⟩
Most eukaryotic mRNAs harbor a characteristic 5′ m7GpppN cap that promotes pre-mRNA splicing, mRNA nucleocytoplasmic transport and translation while also protecting mRNAs from exonucleolytic attacks. mRNA caps are eliminated by Dcp2 during mRNA dec
Autor:
Bertrand Séraphin, Clément Charenton, Régis Back, Valerio Taverniti, Claudine Gaudon-Plesse, Marc Graille
Publikováno v:
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, Nature Publishing Group, 2016, 23 (11), pp.982-986. ⟨10.1038/nsmb.3300⟩
Nature Structural and Molecular Biology, Nature Publishing Group, 2016, 23 (11), pp.982-986. ⟨10.1038/nsmb.3300⟩
The crystal structure of the Kluyveromyces lactis decapping enzyme complex Dcp1–Dcp2 is solved in the presence of activator Edc3 and reaction product m7GDP, revealing an active conformation of the enzyme. Elimination of the 5′ cap of eukaryotic m
Autor:
Olga Kolesnikova, Marc Graille, Claudine Gaudon-Plesse, Valerio Taverniti, Régis Back, Zaineb Fourati, Bertrand Séraphin, Clément Charenton
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (45), pp.E9493-E9501. ⟨10.1073/pnas.1711680114⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2017, 114 (45), pp.E9493-E9501. ⟨10.1073/pnas.1711680114⟩
International audience; The Pat1 protein is a central player of eukaryotic mRNA decay that has also been implicated in translational control. It is commonly considered a central platform responsible for the recruitment of several RNA decay factors. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c90769e7b90a4bbbecb914927438cf9
https://hal-polytechnique.archives-ouvertes.fr/hal-01953029
https://hal-polytechnique.archives-ouvertes.fr/hal-01953029
Autor:
Clément, Charenton, Valerio, Taverniti, Claudine, Gaudon-Plesse, Régis, Back, Bertrand, Séraphin, Marc, Graille
Publikováno v:
Nature structuralmolecular biology. 23(11)
Elimination of the 5' cap of eukaryotic mRNAs, known as decapping, is considered to be a crucial, irreversible and highly regulated step required for the rapid degradation of mRNA by Xrn1, the major cytoplasmic 5'-3' exonuclease. Decapping is accompl
Autor:
Reinhold Tacke, Martin Kaupp, Dino Moras, Christian Burschka, Claudine Gaudon, Natacha Rochel, Hinrich Gronemeyer, Kathrin Götz, Diana Ivanova, W. Peter Lippert, Yoshiteru Sato, Pierre Antony
Publikováno v:
ChemMedChem
ChemMedChem, Wiley-VCH Verlag, 2009, 4 (7), pp.1143-52. ⟨10.1002/cmdc.200900090⟩
ChemMedChem, 2009, 4 (7), pp.1143-52. ⟨10.1002/cmdc.200900090⟩
ChemMedChem, Wiley-VCH Verlag, 2009, 4 (7), pp.1143-52. ⟨10.1002/cmdc.200900090⟩
ChemMedChem, 2009, 4 (7), pp.1143-52. ⟨10.1002/cmdc.200900090⟩
International audience; C/Si switch: Twofold sila-substitution (C/Si exchange) in the RXR-selective retinoids 4 a (SR11237) and 5 a leads to 4 b (disila-SR11237) and 5 b, respectively. Chemistry and biology of the C/Si pairs are reported.SR11237 (BMS
Autor:
Hinrich Gronemeyer, Sarah Sanglier, Vivian Pogenberg, Alain Van Dorsselaer, Mitchell A. Lazar, William Bourguet, Claudine Gaudon, Pierre Germain, Catherine A. Royer
Publikováno v:
Chemistry and Biology
Chemistry and Biology, 2009, 16 (5), pp.479-89. ⟨10.1016/j.chembiol.2009.03.008⟩
Chemistry and Biology, Elsevier, 2009, 16 (5), pp.479-89. ⟨10.1016/j.chembiol.2009.03.008⟩
Chemistry and Biology, 2009, 16 (5), pp.479-89. ⟨10.1016/j.chembiol.2009.03.008⟩
Chemistry and Biology, Elsevier, 2009, 16 (5), pp.479-89. ⟨10.1016/j.chembiol.2009.03.008⟩
International audience; Retinoic acid receptors (RARs) are ligand-dependent transcription factors that control a plethora of physiological processes. RARs exert their functions by regulating gene networks controlling cell growth, differentiation, sur
Autor:
Enrico Garattini, Claudine Gaudon, Ivan Raska, Maurizio Gianni, Emilie Gaillard, Edoardo Parrella, Elisa Agnese Nigro, Cécile Rochette-Egly
Publikováno v:
EMBO Journal
EMBO Journal, EMBO Press, 2006, 25 (4), pp.739-51. ⟨10.1038/sj.emboj.7600981⟩
EMBO Journal, EMBO Press, 2006, 25 (4), pp.739-51. ⟨10.1038/sj.emboj.7600981⟩
International audience; Nuclear retinoic acid (RA) receptors (RARs) activate gene expression through dynamic interactions with coregulators in coordination with the ligand and phosphorylation processes. Here we show that during RA-dependent activatio
Autor:
Ian N. Fleming, Graham Andrew Showell, Claudine Gaudon, Christian Burschka, Jürgen O. Daiss, Diana Ivanova, Hinrich Gronemeyer, John S. Mills, Reinhold Tacke, John Gary Montana
Publikováno v:
Organometallics. 24:3192-3199
Twofold sila-substitution (C/Si exchange) in the saturated ring of the tetrahydronaphthalene skeleton of the RXR-selective retinoid agonist bexarotene (1a) leads to disila-bexarotene (1b). Compound 1b was synthesized in a multistep synthesis, startin
Publikováno v:
The EMBO Journal. 18:2229-2240
Nuclear receptors (NRs) can function as ligandinducible transregulators in both mammalian and yeast cells, indicating that important features of transcriptional control have been conserved throughout evolution. We report here the isolation and charac