Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Claudine G James"'
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8866 (2010)
Endochondral ossification, the process through which long bones are formed, involves chondrocyte proliferation and hypertrophic differentiation in the cartilage growth plate. In a previous publication we showed that pharmacological inhibition of the
Externí odkaz:
https://doaj.org/article/8298fd744a6346a7bd497623d4e2abe5
Autor:
Claudine G James, Lee-Anne Stanton, Hanga Agoston, Veronica Ulici, T Michael Underhill, Frank Beier
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8693 (2010)
Endochondral ossification is a complex process involving a series of events that are initiated by the establishment of a chondrogenic template and culminate in its replacement through the coordinated activity of osteoblasts, osteoclasts and endotheli
Externí odkaz:
https://doaj.org/article/cb0b444e02de4cb08fb6d48545fba2fc
Publikováno v:
Journal of Cellular and Molecular Medicine
Elucidating the signalling pathways that regulate chondrocyte differentiation, such as the actin cytoskeleton and Rho GTPases, during development is essential for understanding of pathological conditions of cartilage, such as chondrodysplasias and os
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::034a4d73445bbcb92717511a7a1c7812
https://doi.org/10.1111/j.1582-4934.2009.00684.x
https://doi.org/10.1111/j.1582-4934.2009.00684.x
Autor:
Claudine G. James, Lee-Anne Stanton, Frank Beier, Veronica Ulici, Hanga Agoston, T. Michael Underhill
Publikováno v:
PLoS ONE
Paediatrics Publications
PLoS ONE, Vol 5, Iss 1, p e8693 (2010)
Paediatrics Publications
PLoS ONE, Vol 5, Iss 1, p e8693 (2010)
Background: Endochondral ossification is a complex process involving a series of events that are initiated by the establishment of a chondrogenic template and culminate in its replacement through the coordinated activity of osteoblasts, osteoclasts a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c44229e08737bba1e2dcf561de613cb
https://pubmed.ncbi.nlm.nih.gov/20084171
https://pubmed.ncbi.nlm.nih.gov/20084171
Publikováno v:
Physiology and Pharmacology Publications
Arthritis Research & Therapy
Arthritis Research & Therapy
Regulated differentiation of chondrocytes is essential for both normal skeletal development and maintenance of articular cartilage. The intracellular pathways that control these events are incompletely understood, and our ability to modulate the chon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a7f163fefe72a7fad1e5b48fb3f312
https://ir.lib.uwo.ca/physpharmpub/15
https://ir.lib.uwo.ca/physpharmpub/15
Publikováno v:
Physiology and Pharmacology Publications
BMC Molecular Biology, Vol 7, Iss 1, p 30 (2006)
BMC Molecular Biology
BMC Molecular Biology, Vol 7, Iss 1, p 30 (2006)
BMC Molecular Biology
BackgroundCoordinated chondrocyte proliferation and differentiation are required for normal endochondral bone growth. Transcription factors binding to the cyclicAMP response element (CRE) are known to regulate these processes. One member of this fami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73a211ba13157fe0824640448c227b07
https://doi.org/10.1186/1471-2199-7-30
https://doi.org/10.1186/1471-2199-7-30
Publikováno v:
Bone and Joint Institute
Control of chondrocyte differentiation is attained, in part, through G-protein signaling, but the functions of the RGS family of genes, well known to control G-protein signaling at the Gα subunit, have not been studied extensively in chondrogenesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d48165243b8b2859b57c0ec1d13431
https://pubmed.ncbi.nlm.nih.gov/16489565
https://pubmed.ncbi.nlm.nih.gov/16489565
Publikováno v:
Bone and Joint Institute
Ordered chondrocyte differentiation and maturation is required for normal skeletal development, but the intracellular pathways regulating this process remain largely unclear. We used Affymetrix microarrays to examine temporal gene expression patterns
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee89d9c3b422b1dd77380f513834ede
https://ir.lib.uwo.ca/boneandjointpub/17
https://ir.lib.uwo.ca/boneandjointpub/17
Publikováno v:
Gene. 342(1)
The type X collagen gene is the classical marker of hypertrophic chondrocytes. Mutations in the human collagen X gene cause metaphyseal chondrodysplasia type Schmid (MCDS). In order to gain insight into the evolution of collagen X genes, we identifie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d2fcb65a16d69fa5683c9c382cf72d
https://pubmed.ncbi.nlm.nih.gov/15573454
https://pubmed.ncbi.nlm.nih.gov/15573454
Publikováno v:
PLoS ONE
Physiology and Pharmacology Publications
PLoS ONE, Vol 5, Iss 1, p e8866 (2010)
Physiology and Pharmacology Publications
PLoS ONE, Vol 5, Iss 1, p e8866 (2010)
Background Endochondral ossification, the process through which long bones are formed, involves chondrocyte proliferation and hypertrophic differentiation in the cartilage growth plate. In a previous publication we showed that pharmacological inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6ae6b04c5a2cacba261de2b53acebe
https://doi.org/10.1371/journal.pone.0008866
https://doi.org/10.1371/journal.pone.0008866