CDX2 expression in the hematopoietic lineage promotes leukemogenesis via TGFβ inhibition

Autor: Ava Galland, Victor Gourain, Karima Habbas, Yonca Güler, Elisabeth Martin, Claudine Ebel, Manuela Tavian, Laurent Vallat, Marie‐Pierre Chenard, Laurent Mauvieux, Jean‐Noël Freund, Isabelle Duluc, Claire Domon‐Dell

Publikováno v: Molecular Oncology, Vol 15, Iss 9, Pp 2318-2329 (2021)

The intestine‐specific caudal‐related homeobox gene‐2 (CDX2) homeobox gene, while being a tumor suppressor in the gut, is ectopically expressed in a large proportion of acute leukemia and is associated with poor prognosis. Here, we report that

Externí odkaz: https://doaj.org/article/897ff20dc4204936a7914f96da43039a

The role of 5-HT2Breceptors in mitral valvulopathy: bone marrow mobilization of endothelial progenitors

Autor: Laurent Monassier, Sophie M. Banas, Jean-Philippe Mazzucotelli, Roland Lawson, Emily Quentin, Francine Côté, Jérôme Guyonnet, Estelle Ayme-Dietrich, Nelly Frossard, François Daubeuf, Bernard Gasser, Christian Gachet, Hélène Rouillard, Sylvia Da Silva, Jordane Stoltz, Béatrice Hechler, Olivier Hermine, Luc Maroteaux, Claudine Ebel, Claudia de Tapia

Publikováno v: British Journal of Pharmacology. 174:4123-4139

Valvular heart disease is highly prevalent in industrialized countries. Chronic use of anorexigens, amphetamine or ergot derivatives targeting the serotonin system has been associated with valvular heart disease.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::698b0b6a0af4c56e2dabec38c2769fd8
https://doi.org/10.1111/bph.13981

Severe combined immunodeficiency in stimulator of interferon genes (STING) V154M/wild-type mice

Autor: Claudine Ebel, Anne-Marie Knapp, Virginia Delgado, Isabelle André-Schmutz, Anne-Sophie Korganow, Pauline Soulas-Sprauel, Delphine Bouis, Delphine Lamon, Nadia Jeremiah, Florent Arbogast, Peggy Kirstetter, Alexandre Belot, Thierry Martin, Frédéric Rieux-Laucat, Yanick J. Crow, Hugues Jacobs, Sophie Jung

Publikováno v: Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology, 2019, 143 (2), pp.712-725.e5. ⟨10.1016/j.jaci.2018.04.034⟩
Journal of Allergy and Clinical Immunology, Elsevier, 2019, 143 (2), pp.712-725.e5. ⟨10.1016/j.jaci.2018.04.034⟩

International audience; Background: Autosomal dominant gain-of-function mutations in human stimulator of interferon genes (STING) lead to a severe autoinflammatory disease called STING-associated vasculopathy with onset in infancy that is associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb9f91c87ed65aaf78c93f21cfb205e
https://pubmed.ncbi.nlm.nih.gov/29800647

The role of 5-HT

Autor: Estelle, Ayme-Dietrich, Roland, Lawson, Francine, Côté, Claudia, de Tapia, Sylvia, Da Silva, Claudine, Ebel, Béatrice, Hechler, Christian, Gachet, Jérome, Guyonnet, Hélène, Rouillard, Jordane, Stoltz, Emily, Quentin, Sophie, Banas, François, Daubeuf, Nelly, Frossard, Bernard, Gasser, Jean-Philippe, Mazzucotelli, Olivier, Hermine, Luc, Maroteaux, Laurent, Monassier

Publikováno v: British journal of pharmacology. 174(22)

Valvular heart disease (VHD) is highly prevalent in industrialized countries. Chronic use of anorexigens, amphetamine or ergot derivatives targeting the 5-HT system is associated with VHD. Here, we investigated the contribution of 5-HT receptors in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::62a8f41c66b3e68655ab38b5d32d98f5
https://pubmed.ncbi.nlm.nih.gov/28806488

Constitutive Activation of the Calcium Sensor STIM1 Causes Tubular-Aggregate Myopathy

Autor: Marc Bartoli, Marc Koch, Jocelyn Laporte, Johann Böhm, Frédéric Chevessier, Martin Krahn, Claudine Ebel, Jean-Michel Vallat, Jean Pouget, Michel Fardeau, Dominique Figarella-Branger, Daniel Hantaï, Karima Ghorab, Bruno Eymard, Shahram Attarian, Pascal Laforêt, André Maues De Paula, Norma B. Romero, Claire Feger, Nicolas Lévy, Catherine Koch

Publikováno v: American Journal of Human Genetics
American Journal of Human Genetics, 2013, 92 (2), pp.271-278. ⟨10.1016/j.ajhg.2012.12.007⟩
American Journal of Human Genetics, Elsevier (Cell Press), 2013, 92 (2), pp.271-278. ⟨10.1016/j.ajhg.2012.12.007⟩

International audience; Tubular aggregates are regular arrays of membrane tubules accumulating in muscle with age. They are found as secondary features in several muscle disorders, including alcohol- and drug-induced myopathies, exercise-induced cram

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6109776a395b316a93a75b549ca23f
https://hal.science/hal-01610022