PPARα in the Epigenetic Driver Seat of NAFLD: New Therapeutic Opportunities for Epigenetic Drugs?

Autor: Claudia Theys, Dorien Lauwers, Claudina Perez-Novo, Wim Vanden Berghe

Publikováno v: Biomedicines, Vol 10, Iss 12, p 3041 (2022)

Nonalcoholic fatty liver disease (NAFLD) is a growing epidemic and the most common cause of chronic liver disease worldwide. It consists of a spectrum of liver disorders ranging from simple steatosis to NASH which predisposes patients to further fibr

Externí odkaz: https://doaj.org/article/48c1e8cd24a7432aad0f0f0921f80f0d

LC-MS Characterization and Biological Activities of Cuban Cultivars of Plectranthus neochilus Schltr

Autor: Annarli O. Rodríguez-Ferreiro, Ania Ochoa-Pacheco, Daniel Méndez-Rodriguez, Emilia Ortiz-Beatón, Oneida Font-Salmo, Frenkel Guisado-Bourzac, Silvia Molina-Bertrán, Lianet Monzote, Paul Cos, Kenn Foubert, Luc Pieters, Claudina Perez-Novo, Wim Vanden Berghe, Julio C. Escalona-Arranz, William N. Setzer

Publikováno v: Plants, Vol 11, Iss 1, p 134 (2022)

Plectranthus neochilus Schltr. (Lamiaceae) is a plant recently introduced in Cuba. Worldwide, it is an ethnomedicinal alternative for its use against microbial infections, but the Cuban population use the extracts to treat sleep disorders. To address

Externí odkaz: https://doaj.org/article/205ae55365704644963ef4f0536352df

Lamin B1 curtails early human papillomavirus infection by safeguarding nuclear compartmentalization and autophagic capacity

Autor: Freya Molenberghs, Marlies Verschuuren, Lauran Vandeweyer, Sarah Peeters, Johannes Bogers, Claudina Perez Novo, Wim Vanden Berghe, Hans De Reu, Nathalie Cools, Mario Schelhaas, Winnok De Vos

Human papillomavirus (HPV) infection is the prime elicitor of cervical and head-and-neck cancers. The HPV genome enters the nucleus during mitosis when the nuclear envelope dismantles. Since lamins safeguard nuclear integrity during interphase, we as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d82bf125114078a010c9782299783ef1
https://doi.org/10.21203/rs.3.rs-1911728/v1

Alterations in cellular force parameters and cell projections in Nasal polyps-derived fibroblasts

Autor: Claudina Perez-Novo, Jônatas Bussador do Amaral, Adriano M. Alencar, A. C. Bloise, Rogério Pezato, Gláucia Maria Machado-Santelli, Carolina Nunes França

Publikováno v: Auris, nasus, larynx
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Objective: Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is a disease that features a mechanical dysfunction involving chronic inflammation and altered tissue remodeling. In this study, we aim to evaluate the fibroblast morphology and its cellula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d8ce23fb5c9e6c750c5083c12617c1b
https://doi.org/10.1016/j.anl.2019.06.007

Echinacea purpurea (L.) Moench treatment of monocytes promotes tonic interferon signaling, increased innate immunity gene expression and DNA repeat hypermethylated silencing of endogenous retroviral sequences

Autor: Ken Declerck, Claudina Perez Novo, Guy Van Camp, Wim Vanden Berghe, Andreas Suter, Lisa Grielens

Publikováno v: BMC COMPLEMENTARY MEDICINE AND THERAPIES
BMC Complementary Medicine and Therapies
BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-20 (2021)

Background Herbal remedies of Echinacea purpurea tinctures are widely used today to reduce common cold respiratory tract infections. Methods Transcriptome, epigenome and kinome profiling allowed a systems biology level characterisation of genomewide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e13af34ebe438a2b5ad4e449d45c8e8
https://biblio.ugent.be/publication/8715267