Zobrazeno 1 - 10
of 438
pro vyhledávání: '"Claudin-Low"'
Autor:
Sara Giovannini, Artem Smirnov, Livia Concetti, Manuel Scimeca, Alessandro Mauriello, Julia Bischof, Valentina Rovella, Gerry Melino, Claudio Oreste Buonomo, Eleonora Candi, Francesca Bernassola
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Breast cancer is the most common cause of death from cancer in women. Here, we present the case of a 43-year-old woman, who received a diagnosis of claudin-low luminal B breast cancer. The lesion revealed to be a poorly differentiated high-g
Externí odkaz:
https://doaj.org/article/ccdd64d0c6924cd9a3773406e9be3184
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
Externí odkaz:
https://doaj.org/article/ee338860fd10430a958559bc1a3c15a8
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Claudin-low breast cancer (CLBC) is a subgroup of breast cancer discovered at the molecular level in 2007. Claudin is one of the primary proteins that make up tight junctions, and it plays crucial roles in anti-inflammatory and antitumor responses as
Externí odkaz:
https://doaj.org/article/04b86a8d03ff49c193bc0b843e2eccc6
Akademický článek
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Autor:
Yu Hin Tang, Anja Rockstroh, Kamil A. Sokolowski, Layla-Rose Lynam, Melanie Lehman, Erik W. Thompson, Philip A. Gregory, Colleen C. Nelson, Marianna Volpert, Brett G. Hollier
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-17 (2022)
Abstract Background Triple-negative breast cancers (TNBC) have a relatively poor prognosis and responses to targeted therapies. Between 25 and 39% of TNBCs are claudin-low, a poorly differentiated subtype enriched for mesenchymal, stem cell and mitog
Externí odkaz:
https://doaj.org/article/684155e1b55647e9a6a13d4ab5bc7d5f
Autor:
Huizhi Sun, Yanlei Li, Yanhui Zhang, Xiulan Zhao, Xueyi Dong, Yuhong Guo, Jing Mo, Na Che, Xinchao Ban, Fan Li, Xiaoyu Bai, Yue Li, Jihui Hao, Danfang Zhang
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionHypoxia is an important characteristic of solid tumors. However, spatial transcriptomics (ST) of hypoxia-associated heterogeneity is not clear.MethodsThis study integrated Spatial Transcriptomics (ST) with immunofluorescence to demonstrat
Externí odkaz:
https://doaj.org/article/c3b25f10ed784398a6b4b85d3dd20e1d
Akademický článek
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Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-16 (2021)
Abstract Background MicroRNAs are a class of non-coding RNAs that regulate gene expression through binding to mRNAs and preventing their translation. One family of microRNAs known as the miR-200 family is an important regulator of epithelial identity
Externí odkaz:
https://doaj.org/article/a4d5ae2f6c064127848efd4e3c5a6fae
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Breast cancer (BCa) is the most common malignancy in women and claudin-low breast cancer (CL-BCa) is a newly identified BCa subtype characterized by low expression of claudin 3&4&7. However, the hub genes associated with the recruitment of immune cel
Externí odkaz:
https://doaj.org/article/59083d24b7d940829959edfb9bff737f
Publikováno v:
Cancer Management and Research, Vol Volume 12, Pp 2641-2651 (2020)
Jun Chang,1,2 Ling Hong,2 Yaozhong Liu,3 Yiwen Pan,2 Hao Yang,2 Wenrui Ye,3 Keli Xu,4 Zhijian Li,1 Shubing Zhang1,2,5,6 1Department of Anesthesiology, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, People’s Republi
Externí odkaz:
https://doaj.org/article/547e16454c2b40dca265515d48ce251c