Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Claudia von Zimmermann"'
Autor:
Razvan-Marius Brazdis, Claudia von Zimmermann, Bernd Lenz, Johannes Kornhuber, Christiane Mühle
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3219 (2024)
Due to the high comorbidity of Parkinson’s disease (PD) with major depressive disorder (MDD) and the involvement of sphingolipids in both conditions, we investigated the peripheral expression levels of three primarily PD-associated genes: α-synucl
Externí odkaz:
https://doaj.org/article/6d2fcff38f2848ccba7ade5a7a01ab7a
Autor:
Claudia von Zimmermann, Lena Brückner, Christiane Mühle, Christian Weinland, Johannes Kornhuber, Bernd Lenz
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
BackgroundMajor depressive disorder (MDD) is a main reason for suicide, and serum lipids are involved in both affective disorders and related suicidal behavior. Moreover, masculine depression has been suggested as a subtype of depression with an incr
Externí odkaz:
https://doaj.org/article/4bd6b4d475ac4e189a9bef8ea622a088
Autor:
Caroline Swoboda, Lena Deloch, Claudia von Zimmermann, Tanja Richter-Schmidinger, Bernd Lenz, Johannes Kornhuber, Christiane Mühle
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15460 (2022)
Macrophage migration inhibitory factor (MIF) is a controversially discussed inflammatory marker in major depressive disorder (MDD). While some studies show an association of high MIF protein levels with depression, animal models have yielded conflict
Externí odkaz:
https://doaj.org/article/c1aac897e9a04fb38b07cb41a7c61478
Autor:
Christiane Mühle, Massimiliano Mazza, Christian Weinland, Claudia von Zimmermann, Patrick Bach, Falk Kiefer, Valery Grinevich, Iulia Zoicas, Johannes Kornhuber, Bernd Lenz
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9940 (2022)
Alcohol use disorder (AUD) is a major global mental health challenge. Knowledge concerning mechanisms underlying AUD and predictive biomarkers of AUD progression and relapse are insufficient. Recently, addiction research is focusing attention on the
Externí odkaz:
https://doaj.org/article/132fb5b5bce9480390a3b7a63968f340
Autor:
Claudia von Zimmermann, Merle Winkelmann, Tanja Richter-Schmidinger, Christiane Mühle, Johannes Kornhuber, Bernd Lenz
Publikováno v:
Frontiers in Psychiatry, Vol 11 (2020)
BackgroundPhysical activity and a healthy body composition are said to reduce the risk of major depressive disorder. Nonetheless, deeper insight is needed into which specific forms of physical activity (and their relation to body composition) are eff
Externí odkaz:
https://doaj.org/article/8eb9300222ca4411bdc1c2fe05077527
Autor:
Cosima Rhein, Iulia Zoicas, Lena M. Marx, Stefanie Zeitler, Tobias Hepp, Claudia von Zimmermann, Christiane Mühle, Tanja Richter-Schmidinger, Bernd Lenz, Yesim Erim, Martin Reichel, Erich Gulbins, Johannes Kornhuber
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 5700 (2021)
Major depressive disorder (MDD) is a severe psychiatric condition with key symptoms of low mood and lack of motivation, joy, and pleasure. Recently, the acid sphingomyelinase (ASM)/ceramide system has been implicated in the pathogenesis of MDD. ASM i
Externí odkaz:
https://doaj.org/article/410c77b0b64b4afc83f69d33cedfb4a1
Autor:
Claudia von Zimmermann, Magdalena Hübner, Christiane Mühle, Christian P. Müller, Christian Weinland, Johannes Kornhuber, Bernd Lenz
Publikováno v:
European Archives of Psychiatry and Clinical Neuroscience.
The gender role influences vulnerability to mental illness. Substance use, even critical in scale, is perceived as masculine, just like hard (over-)work, while not seeking help. With the ongoing separation between gender and sex, masculine norms beco
Publikováno v:
Addiction Biology. 27
Previous studies have established a role of sex hormones in alcohol use disorder (AUD).Only few clinical investigations with low numbers of patients with AUD have focused on the sulphated form of dehydroepiandrosterone (DHEA-S), despite its function
Autor:
Cosima, Rhein, Iulia, Zoicas, Lena M, Marx, Stefanie, Zeitler, Tobias, Hepp, Claudia, von Zimmermann, Christiane, Mühle, Tanja, Richter-Schmidinger, Bernd, Lenz, Yesim, Erim, Martin, Reichel, Erich, Gulbins, Johannes, Kornhuber
Publikováno v:
International Journal of Molecular Sciences
Major depressive disorder (MDD) is a severe psychiatric condition with key symptoms of low mood and lack of motivation, joy, and pleasure. Recently, the acid sphingomyelinase (ASM)/ceramide system has been implicated in the pathogenesis of MDD. ASM i
Autor:
Christiane Mühle, Lea Böhm, Tanja Richter-Schmidinger, Claudia von Zimmermann, Bernd Lenz, Johannes Kornhuber
Publikováno v:
Journal of Neural Transmission
Directly measuring hypothalamic pituitary adrenal (HPA) axis function, an important player in affective disorders, is intensive and invasive. A crucial component of this system, the activity of the glucocorticoid receptor (GR), can be assessed ex viv