Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Claudia Weidler"'
Autor:
Silvia Capellino, Torsten Lowin, Frank Buttgereit, Claudia Weidler, Zsuzsa Jenei-Lanzl, Rainer H. Straub, Christoph Baerwald
Publikováno v:
Arthritis & Rheumatism. 64:1799-1808
Objective Proliferating pannus is in many aspects similar to placental tissue. Both fibroblast-rich tissues have high vascularity, and tissue from patients with rheumatoid arthritis (RA) and patients with osteoarthritis (OA) demonstrates conversion o
Autor:
Sebastian Häusler, Claudia Weidler, Yvonne Dombrowski, Mathias Krockenberger, Jörg Wischhusen, Jörg B. Engel, Tanja Schönhals, Arnd Honig, Johannes Dietl, Thomas G. P. Grunewald, Lorenz Rieger
Publikováno v:
European Journal of Obstetrics & Gynecology and Reproductive Biology. 141:64-69
Objective Perifosine is an orally active alkylphospholipid analog, which has shown anti-tumor activity in a variety of cancers by inhibition of AKT phosphorylation. The objective of the current study was to evaluate its efficacy in in vitro models of
Autor:
Sebastian Häusler, Heike Voigt, Richard Bucala, Arnd Honig, Claudia Weidler, Jörg Wischhusen, Lin Leng, Johannes Dietl, Mathias Krockenberger, Monika Ossadnik, Yvonne Dombrowski, Michael Weller, Alexander Steinle, Jürgen C. Becker
Publikováno v:
Queen's University Belfast-PURE
The proinflammatory cytokine macrophage migration inhibitory factor (MIF) stimulates tumor cell proliferation, migration, and metastasis; promotes tumor angiogenesis; suppresses p53-mediated apoptosis; and inhibits antitumor immunity by largely unkno
Autor:
Hans-Jörg Linde, Rainer H. Straub, Carsten J. Kirschning, Werner Falk, Thomas Glück, Claudia Weidler, Georg Pongratz, Jürgen Schölmerich
Publikováno v:
The Journal of Infectious Diseases. 192:560-572
The sympathetic nervous system is intensely activated during bacteremia, but its immediate influence on the bacterial tissue burden remains unclear. We demonstrate that prior ablation of the sympathetic nervous system decreases this dissemination of
Publikováno v:
Annals of the Rheumatic Diseases. 64:1083-1086
Objectives: To identify and characterise nerve fibres and inflammatory alterations in painful Achilles tendinosis and thus gain evidence about the origin of pain in Achilles tendinosis. Methods: The composition of 10 tendon samples from patients with
Autor:
Bernhard Ugele, Jürgen Schölmerich, Claudia Weidler, Martin Schmidt, Sona Struharova, Rainer H. Straub
Publikováno v:
Arthritis & Rheumatism. 52:1721-1729
Objective Use of anti–tumor necrosis factor (anti-TNF) antibody therapy in rheumatoid arthritis (RA) has expanded our understanding of possible mechanisms by which this treatment reduces inflammation. Beyond its effects on local immune responses, a
Autor:
C Holzer, Claudia Weidler, J Schölmerich, M Harbuz, Rainer H. Straub, Rafael Hofbauer, Peter Angele
Publikováno v:
Annals of the Rheumatic Diseases. 64:13-20
Objective: To investigate the correlation between density of nerve fibres and the presence of BDNF+ cells. Methods: Densities of nerve fibres and BDNF+ cells were detected by quantitative immunohistochemistry in fresh synovial tissue from 52 patients
Autor:
Martin Schmidt, Jörg Schedel, Markus Herrmann, B Demmel, Claudia Weidler, Frieder Kees, J Schölmerich, Rainer H. Straub
Publikováno v:
Annals of the Rheumatic Diseases. 63:961-968
Background: In rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), patients demonstrate low levels of adrenal hormones. Objective: To investigate whether increased renal clearance and daily excretion contribute to this phenomenon. Metho
Autor:
Luitpold E. Miller, Rainer H. Straub, Werner Falk, Jens Schaumburger, Peter Angele, Jürgen Schölmerich, Claudia Weidler
Publikováno v:
Arthritis & Rheumatism. 50:1156-1163
Objective The presence of selective sympathetic nerve repellents, i.e., semaphorins, may be responsible for the observed reduction of sympathetic innervation in the synovial tissue of patients with rheumatoid arthritis (RA). This study was undertaken
Autor:
Arnd Honig, Jörg Wischhusen, Lorenz Rieger, Claudia Weidler, Tanja Schönhals, Mathias Krockenberger, Sebastian Häusler, Jörg B. Engel, Johannes Dietl
Publikováno v:
Oncology reports. 22(2)
AEZS 112 is an orally active small molecule anticancer drug which inhibits the polymerization of tubulin at low micromolar concentrations. The current study investigates the anti-tumor effect and the mechanism of action of AEZS 112 in in vitro models