Proinflammatory mucosal-associated invariant CD8+ T cells react to gut flora yeasts and infiltrate multiple sclerosis brain

Autor: Francesca Gargano, Gisella Guerrera, Eleonora Piras, Barbara Serafini, Monica Di Paola, Lisa Rizzetto, Maria Chiara Buscarinu, Viviana Annibali, Claudia Vuotto, Marco De Bardi, Silvia D’Orso, Serena Ruggieri, Claudio Gasperini, Lorenzo Pavarini, Giovanni Ristori, Mario Picozza, Barbara Rosicarelli, Clara Ballerini, Rosella Mechelli, Francesco Vitali, Duccio Cavalieri, Marco Salvetti, Daniela F. Angelini, Giovanna Borsellino, Carlotta De Filippo, Luca Battistini

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

The composition of the intestinal microbiota plays a critical role in shaping the immune system. Modern lifestyle, the inappropriate use of antibiotics, and exposure to pollution have significantly affected the composition of commensal microorganisms

Externí odkaz: https://doaj.org/article/f7cbdaa66c3d48839d8d7721b91190c1

Synthesis of Novel Hyaluronic Acid Sulfonated Hydrogels Using Safe Reactants: A Chemical and Biological Characterization

Autor: Elisa Sturabotti, Silvia Consalvi, Luca Tucciarone, Elisa Macrì, Valerio Di Lisio, Iolanda Francolini, Carmen Minichiello, Antonella Piozzi, Claudia Vuotto, Andrea Martinelli

Publikováno v: Gels, Vol 8, Iss 8, p 480 (2022)

Here, we present a one-pot procedure for the preparation of hyaluronic acid (HA) sulfonated hydrogels in aqueous alkaline medium. The HA hydrogels were crosslinked using 1,4-butanedioldiglycidyl ether (BDDE) alone, or together with N-bis(2-hydroxyeth

Externí odkaz: https://doaj.org/article/17bcedbd315b4019ad7a5662f4cc665c

Role of Daptomycin in the Induction and Persistence of the Viable but Non-Culturable State of Staphylococcus Aureus Biofilms

Autor: Sonia Pasquaroli, Barbara Citterio, Andrea Di Cesare, Mehdi Amiri, Anita Manti, Claudia Vuotto, Francesca Biavasco

Publikováno v: Pathogens, Vol 3, Iss 3, Pp 759-768 (2014)

We have recently demonstrated that antibiotic pressure can induce the viable but non-culturable (VBNC) state in Staphylococcus aureus biofilms. Since dormant bacterial cells can undermine anti-infective therapy, a greater understanding of the role of

Externí odkaz: https://doaj.org/article/c290260249b640b8973a5149b6786e7c

Antimicrobial ‘Inks’ for 3D Printing: Block Copolymer-Silver Nanoparticle Composites Synthesised Using Supercritical CO2

Autor: Ryan R. Larder, Eduards Krumins, Philippa L. Jacob, Kristoffer Kortsen, Robert Cavanagh, Long Jiang, Claudia Vuotto, Iolanda Francolini, Christopher Tuck, Vincenzo Taresco, Steven M. Howdle

Publikováno v: Kortsen, K 2022, ' Antimicrobial ‘Inks’ for 3D Printing: Block Copolymer-Silver Nanoparticle Composites Synthesised Using Supercritical CO2 ', Polymer Chemistry, vol. 13, no. 25, pp. 3768-3779 . https://doi.org/10.1039/d2py00398h

Silver nanoparticles (AgNP) are widely exploited for their effective antimicrobial activity against a range of pathogens. Their high efficacy in this regard has seen the global demand for AgNP in consumer products steadily increase in recent years, n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b939120a6e2e1f28840a01a64231a106
https://research.manchester.ac.uk/en/publications/af8309cc-8799-492c-bacc-1e53daa5dae9

Novel Treatment Strategies for Biofilm-Based Infections

Autor: Claudia Vuotto, Gianfranco Donelli

Publikováno v: Drugs. 79:1635-1655

Biofilm-growing cells show an enhanced antimicrobial tolerance with respect to the same cells growing in a free-floating way. This is due to physical or chemical diffusion barriers and increased transfer of resistance markers. Thus, tissue- and medic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::883f44b4cd50c8741648af0301b12561
https://doi.org/10.1007/s40265-019-01184-z