Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Claudia Von Arx"'
Autor:
Aurora Costa, Iris Maria Forte, Francesca Pentimalli, Carmelina Antonella Iannuzzi, Luigi Alfano, Francesca Capone, Rosa Camerlingo, Alessandra Calabrese, Claudia von Arx, Reyes Benot Dominguez, Massimiliano Quintiliani, Michelino De Laurentiis, Andrea Morrione, Antonio Giordano
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionDiffuse pleural mesothelioma (DPM) of the pleura is a highly aggressive and treatment-resistant cancer linked to asbestos exposure. Despite multimodal treatment, the prognosis for DPM patients remains very poor, with an average survival o
Externí odkaz:
https://doaj.org/article/b853fb46d9b3462d81cf3795b07f7ee6
Autor:
Alessandro Ottaiano, Massimiliano Berretta, Claudia Von Arx, Monica Capozzi, Michele Caraglia
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/34bae374e3ac481c813385696db6178e
Autor:
James R. Birtley, Mohammad Alomary, Elisa Zanini, Jane Antony, Zachary Maben, Grant C. Weaver, Claudia Von Arx, Manuela Mura, Aline T. Marinho, Haonan Lu, Eloise V. N. Morecroft, Evdoxia Karali, Naomi E. Chayen, Edward W. Tate, Mollie Jurewicz, Lawrence J. Stern, Chiara Recchi, Hani Gabra
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
OPCML is a tumour suppressor gene that is epigenetically silenced in ovarian cancer and is somatically mutated in various cancers. Here, the authors solve the X-ray crystal structure of OPCML and model clinically relevant mutations that could contrib
Externí odkaz:
https://doaj.org/article/0d39746c3dc44914b53cf2c2f0ee8062
Autor:
Valentina Massa, Andrea Sbrana, Fortunato Ciardiello, Carminia Maria Della Corte, Floriana Morgillo, Dario Trapani, Sandro Pignata, Antonio Avallone, Vincenzo Montesarchio, Marco Messina, Paolo Antonio Ascierto, Ester Simeone, Antonio Maria Grimaldi, Marcello Curvietto, Lucia Festino, Michela Lia, Giacomo Cartenì, Luisa Piccin, Bruno Daniele, Sabino De Placido, Cesare Gridelli, Stefano Pepe, Vito Vanella, Giuseppe Palmieri, Maria Grazia Vitale, Alessandro Morabito, Margaret Ottaviano, Pasquale Rescigno, Marianna Tortora, Giovannella Palmieri, Michele Aieta, Pasquale Assalone, Laura Attademo, Francesco Bloise, Davide Bosso, Valentina Borzillo, Giuseppe Buono, Giuseppe Calderoni, Francesca Caputo, Diletta Cavallero, Alessia Cavo, Raffaele Conca, Vincenza Conteduca, Stefano De Falco, Marco De Felice, Michelino De Laurentiis, Pietro De Placido, Irene De Santo, Alfonso De Stefano, Rossella Di Franco, Vincenzo Di Lauro, Antonietta Fabbrocini, Piera Federico, Pasqualina Giordano, Mario Giuliano, Antonella Lucia Marretta, Alessia Mennitto, Sara Merler, Valeria Merz, Carlo Messina, Monica Milano, Alessandro Marco Minisini, Brigitta Mucci, Lucia Nappi, Fabiana Napolitano, Immacolata Paciolla, Martina Pagliuca, Sara Parola, Angelica Petrillo, Francovito Piantedosi, Fernanda Picozzi, Erica Pietroluongo, Veronica Prati, Vittorio Riccio, Mario Rosanova, Alice Rossi, Anna Russo, Massimiliano Salati, Giuseppe Santabarbara, Antonia Silvestri, Massimiliano Spada, Paolo Tarantino, Paola Taveggia, Federica Tomei, Tortora Vincenzo, Claudia Trojanello, Sabrina Vari, Jole Ventriglia, Fabiana Vitiello, Caterina Vivaldi, Claudia von Arx, Francesca Zacchi, Ilaria Zampiva, Andrea Zivi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background The coronavirus disease 2019 (COVID-19) pandemic has overwhelmed the health systems worldwide. Data regarding the impact of COVID-19 on cancer patients (CPs) undergoing or candidate for immune checkpoint inhibitors (ICIs) are lacking. We d
Externí odkaz:
https://doaj.org/article/64743faa9b7a4b10b9520d6339d9ebce
Autor:
Antonella Lucia Marretta, Giuseppe Di Lorenzo, Dario Ribera, Lucia Cannella, Claudia von Arx, Alessandra Bracigliano, Ottavia Clemente, Roberto Tafuto, Antonio Pizzolorusso, Salvatore Tafuto
Publikováno v:
Pharmaceutics, Vol 13, Iss 9, p 1522 (2021)
Nucleocytoplasmic transport has been found dysregulated in many types of cancer and is often described as a poor prognostic factor. Specifically, Exportin-1 (XPO1) has been found overexpressed in many tumors and has become an attractive target in mol
Externí odkaz:
https://doaj.org/article/8b23c6cc2463492394dd68d9b27c4eae
Autor:
Michela Piezzo, Roberta D’Aniello, Ilaria Avallone, Bruno Barba, Daniela Cianniello, Stefania Cocco, Antonio D’Avino, Germira Di Gioia, Vincenzo Di Lauro, Giuseppina Fusco, Raffaele Piscitelli, Claudia von Arx, Michelino De Laurentiis, Piera Maiolino
Publikováno v:
Pharmaceutics, Vol 13, Iss 5, p 684 (2021)
Background: The introduction of trastuzumab biosimilars in clinical practice plays an important role in promoting the sustainability of healthcare systems. By contrast, the switching process can be challenging to the clinics. This survey describes th
Externí odkaz:
https://doaj.org/article/606ff46d6a98435db203621155ad3571
Autor:
Lucia Cannella, Francesco Perri, Ottavia Clemente, Claudia von Arx, Antonio Pizzolorusso, Maurizio Di Bonito, Alessandra Bracigliano, Massimiliano Di Marzo, Giuseppina Della Vittoria Scarpati, Annarosaria De Chiara, Salvatore Tafuto
Publikováno v:
Oncology. 101:234-239
Background/Aim: Breast angiosarcoma is a rare and aggressive disease with a poor prognosis. Two subtypes have been identified: primary angiosarcoma (PBA) and secondary breast angiosarcoma (SBA). In this retrospective analysis, we describe and compare
Autor:
Claudia von Arx, Pietro De Placido, Aldo Caltavituro, Rossana Di Rienzo, Roberto Buonaiuto, Michelino De Laurentiis, Grazia Arpino, Fabio Puglisi, Mario Giuliano, Lucia Del Mastro
Publikováno v:
Cancer treatment reviews. 113
A novel class of drugs, antibody-drug conjugates (ADCs), are now rapidly emerging as highly effective treatments for solid tumours. ADCs conjugate conventional chemotherapeutics with highly selective targeted monoclonal antibodies. Anti-HER2 therapie
Autor:
Salvatore Tafuto, Antonio Pizzolorusso, Claudia von Arx, Lucia Cannella, Antonella Lucia Marretta, Dario Ribera, Giuseppe Di Lorenzo, Roberto Tafuto, Alessandra Bracigliano, Ottavia Clemente
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 13, Iss 1522, p 1522 (2021)
Pharmaceutics, Vol 13, Iss 1522, p 1522 (2021)
Nucleocytoplasmic transport has been found dysregulated in many types of cancer and is often described as a poor prognostic factor. Specifically, Exportin-1 (XPO1) has been found overexpressed in many tumors and has become an attractive target in mol
Autor:
Haonan Lu, Mohammad N. Alomary, Hani Gabra, Chiara Recchi, Evdoxia Karali, Edward W. Tate, Naomi E. Chayen, Manuela Mura, Zachary Maben, Grant C. Weaver, Aline T. Marinho, Mollie Jurewicz, James R. Birtley, Eloise V. N. Morecroft, Lawrence J. Stern, Jane Antony, Claudia von Arx, Elisa Zanini
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications
Nature Communications
OPCML, a tumor suppressor gene, is frequently silenced epigenetically in ovarian and other cancers. Here we report, by analysis of databases of tumor sequences, the observation of OPCML somatic missense mutations from various tumor types and the impa