Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Claudia T Mendler"'
Autor:
Volker Morath, Corinna Brandt, Friedrich-Christian Deuschle, Claudia T. Mendler, Birgit Blechert, Dominik Summer, Cyril Barinka, Clemens Decristoforo, Wolfgang A. Weber, Markus Schwaiger, Arne Skerra
Publikováno v:
Molecular Pharmaceutics. 20:2490-2501
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce1dbf5d82b8a134f8cc4262ee2c0303
https://doi.org/10.1021/acs.molpharmaceut.2c01066
https://doi.org/10.1021/acs.molpharmaceut.2c01066
Autor:
Marcus D Hartmann, Claudia T Mendler, Jens Bassler, Ioanna Karamichali, Oswin Ridderbusch, Andrei N Lupas, Birte Hernandez Alvarez
Publikováno v:
eLife, Vol 5 (2016)
Coiled coils are the best-understood protein fold, as their backbone structure can uniquely be described by parametric equations. This level of understanding has allowed their manipulation in unprecedented detail. They do not seem a likely source of
Externí odkaz:
https://doaj.org/article/bacd4c1864cb498a8575e4279f309a77
Autor:
Karina Knorr, Claudia T Mendler, Marion Kiechle, Stephanie Robu, Martin Schlapschy, Antonia Richter, Hsi-Yu Yen, Volker Morath, Arne Skerra, Katja Steiger, Markus Schwaiger, Wolfgang A. Weber
Publikováno v:
Nuclear Medicine and Molecular Imaging. 54:114-119
Purpose PASylation® offers the ability to systematically tune and optimize the pharmacokinetics of protein tracers for molecular imaging. Here we report the first clinical translation of a PASylated Fab fragment (89Zr∙Df-HER2-Fab-PAS200) for the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3c2cb6f584ae9084f0be0dcf3a11e85
https://doi.org/10.1007/s13139-020-00638-7
https://doi.org/10.1007/s13139-020-00638-7
Autor:
Axel Walch, Michaela Aichler, Hans-Jürgen Wester, Birgit Blechert, Claudia T Mendler, Rickmer Braren, Calogero D'Alessandria, Arne Skerra, Sabine Pirsig, Markus Schwaiger, Annette Feuchtinger, Irina Heid
Publikováno v:
Journal of Nuclear Medicine. 57:1971-1977
Antibodies have become an established treatment modality in cancer therapy during the last decade. However, these treatments often suffer from an insufficient and heterogeneous response despite validated antigen or target receptor expression in the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b5931bed8ba4df886249139712ae41
https://doi.org/10.2967/jnumed.116.176784
https://doi.org/10.2967/jnumed.116.176784
Publikováno v:
Journal of Nuclear Medicine. 56:1112-1118
Immuno-PET imaging of the tumor antigen HER2/neu allows for the noninvasive detection and monitoring of oncogene expression; such detection and monitoring are of prognostic value in patients with breast cancer. Compared with the full-size antibody tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e38ca0a8638b9e3b2b41828ffc7e2f7
https://doi.org/10.2967/jnumed.114.149690
https://doi.org/10.2967/jnumed.114.149690
Autor:
Markus Schwaiger, Hans-Jürgen Wester, Iina Laitinen, Claudia T Mendler, Arne Skerra, Martin Schlapschy, Lars Friedrich
Publikováno v:
mAbs
Although antigen-binding fragments (Fabs) of antibodies constitute established tracers for in vivo radiodiagnostics, their functionality is hampered by a very short circulation half-life. PASylation, the genetic fusion with a long, conformationally d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b51e6f556da619de13c8b19cd187de
http://europepmc.org/articles/PMC4622060
http://europepmc.org/articles/PMC4622060
Autor:
Birte Hernandez Alvarez, Ioanna Karamichali, Claudia T Mendler, O. Ridderbusch, Marcus D. Hartmann, Andrei N. Lupas, Jens Bassler
Publikováno v:
eLife
eLife, Vol 5 (2016)
eLife, Vol 5 (2016)
Coiled coils are the best-understood protein fold, as their backbone structure can uniquely be described by parametric equations. This level of understanding has allowed their manipulation in unprecedented detail. They do not seem a likely source of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7208164f9b43be1f8dc29ea3af98e674
https://doi.org/10.7554/elife.11861
https://doi.org/10.7554/elife.11861
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 56(7)
Immuno-PET imaging of the tumor antigen HER2/neu allows for the noninvasive detection and monitoring of oncogene expression; such detection and monitoring are of prognostic value in patients with breast cancer. Compared with the full-size antibody tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::93fab86bb72eaf8afbb8e569f47d30d9
https://pubmed.ncbi.nlm.nih.gov/25999431
https://pubmed.ncbi.nlm.nih.gov/25999431
Autor:
Friedrich, Lars, Kornberger, Petra, Mendler, Claudia T., Multhoff, Gabriele, Schwaiger, Markus, Skerra, Arne
Publikováno v:
Biological Chemistry; Mar2018, Vol. 399 Issue 3, p235-252, 18p, 4 Diagrams, 2 Charts, 4 Graphs