Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Claudia Seul"'
Publikováno v:
Cellular Signalling. 13:787-799
In order to identify differentially expressed genes under growth conditions, quiescent vascular smooth muscle cells (VSMCs) were stimulated with foetal calf serum (FCS) or platelet-derived growth factor-BB (PDGF-BB) for different time periods. Analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be7ecfe3c06c3480cc40f3def298276
https://doi.org/10.1016/s0898-6568(01)00198-x
https://doi.org/10.1016/s0898-6568(01)00198-x
Autor:
Claudia Seul, Heiner K. Berthold, Agapios Sachinidis, Ioanna Gouni-Berthold, Hans Vetter, Yon Ko
Publikováno v:
British Journal of Pharmacology. 132:1725-1734
There are contradictory findings regarding the effects of free fatty acids on vascular smooth muscle cell (VSMC) growth. In the present study we investigated the effects of fatty acids released from hydrolysis of human VLDL triglycerides by lipoprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5554dd3f42cbcd075c8a9a83c4023ac4
https://doi.org/10.1038/sj.bjp.0704026
https://doi.org/10.1038/sj.bjp.0704026
Autor:
Claudia Seul, Gouni-Berthold I, Hans Vetter, Agapios Sachinidis, Ko Yd, Stefan Seewald, Berthold Hk
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 60:723-731
Growth factors such as the platelet-derived growth factor (PDGF)-BB and angiotensin II (Ang II) have been shown to induce vascular smooth muscle cell (VSMC) proliferation after long stimulation periods. Little is known though, about the effects of PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d6e2b479fe21826f37de6d7f4486fa9
https://doi.org/10.1080/00365510050216457
https://doi.org/10.1080/00365510050216457
Autor:
Hans Vetter, Ioanna Gouni-Berthold, Claudia Seul, Udo Schmitz, Stefan Seewald, Yon Ko, Agapios Sachinidis
Publikováno v:
British Journal of Pharmacology. 128:1761-1771
ERKs belong to MAP kinase family and are activated by several growth and stress factors. Although ethanol has been shown to modulate ERK1 and ERK2 (p44mapk and p42mapk) activity, it can also act as an antiproliferative agent in various mammalian cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5033c7f1bfea5b39c86b1fd75f185beb
https://doi.org/10.1038/sj.bjp.0702969
https://doi.org/10.1038/sj.bjp.0702969
Autor:
Udo Schmitz, Agapios Sachinidis, Stefan Seewald, Claudia Seul, Ralf Kettenhofen, Ioanna Gouni-Berthold, Hans Vetter, Yon Ko
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 19:2412-2421
Abstract —We recently demonstrated that the mitogenic effect of LDL (100 μg/mL) as well as its early intracellular signaling pathway are mediated by a pertussis-toxin (PTX)-sensitive G i protein-coupled receptor that is independent from its classi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8710b31d217138026242a2ad76f69d
https://doi.org/10.1161/01.atv.19.10.2412
https://doi.org/10.1161/01.atv.19.10.2412
Publikováno v:
American Journal of Hypertension. 12:532-537
The natural phospholipid lysophosphatidic acid (LPA) has been characterized as an important vascular smooth muscle cell (VSMC) mitogen whose effects are mainly mediated by pertussis toxin (PTX)-sensitive guanosine triphosphate (GTP)-binding protein (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5e7042436c1bb33dd93a50824f58ec7
https://doi.org/10.1016/s0895-7061(98)00269-6
https://doi.org/10.1016/s0895-7061(98)00269-6
Autor:
Yeo-Pyo Yun, Hee-Yul Ahn, Agapios Sachinidis, Hans Vetter, Kourosch Reza Hadizadeh, Claudia Seul
Publikováno v:
Molecular Biology of the Cell. 10:1093-1104
Enhanced activity of receptor tyrosine kinases such as the PDGF β-receptor and EGF receptor has been implicated as a contributing factor in the development of malignant and nonmalignant proliferative diseases such as cancer and atherosclerosis. Seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f49fb47690c4adcc313b9679e6c3425a
https://doi.org/10.1091/mbc.10.4.1093
https://doi.org/10.1091/mbc.10.4.1093
Autor:
Stefan Seewald, Hans Vetter, Dirk Bokemeyer, Yon Ko, Agapios Sachinidis, Ralf Kettenhofen, Claudia Seul
Publikováno v:
Hypertension. 31:1151-1156
Abstract —The activation of mitogen-activated protein (MAP) kinase and increase in intracellular free calcium concentration ([Ca 2+ ] i ) are discussed in reference to activation of different protein kinases and growth of vascular smooth muscle cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::593d5b83d4d938e34081e399888c7c63
https://doi.org/10.1161/01.hyp.31.5.1151
https://doi.org/10.1161/01.hyp.31.5.1151
Autor:
Stefan Seewald, Hans Vetter, Agapios Sachinidis, Yon Ko, Claudia Seul, Artur-Aron Weber, Volker Harth
Publikováno v:
British Journal of Pharmacology. 123:906-910
1. The composition of glycosphingolipids is altered in atherosclerotic tissue. In order to study the possible modulation of interleukin-1beta (IL-1beta)-induced expression of inducible nitric oxide synthase (iNOS) by endogenously synthesized glycosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cc347e3db18c2b78418f73775111421
https://doi.org/10.1038/sj.bjp.0701674
https://doi.org/10.1038/sj.bjp.0701674
Publikováno v:
Molecular Pharmacology. 52:389-397
Low-density lipoprotein (LDL) is known to be a mitogenic factor for vascular smooth muscle cells (VSMCs), fibroblasts, and endothelial cells. In the current study, we describe possible intracellular mechanisms by which LDL elicits its mitogenic effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c06f20dd8cedc25d29391415504c49
https://doi.org/10.1124/mol.52.3.389
https://doi.org/10.1124/mol.52.3.389