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pro vyhledávání: '"Claudia Rivera-Guevara"'
Autor:
Claudia Rivera-Guevara, Javier Camacho
Publikováno v:
Recent Patents on Anti-Cancer Drug Discovery. 6:237-245
A major challenge in cancer research is to discover drugs with high selectivity and minor side-effects. Tamoxifen has been widely used for more than 30 years in breast cancer treatment and prevention. Tamoxifen acts mainly via estrogen receptors (ER)
Autor:
Víctor Pérez-Álvarez, Javier Camacho, Elizabeth Hernández-Gallegos, Martha S. Morales-Rios, David Ordaz-Rosado, Fernando Larrea, Claudia Rivera-Guevara, Rocío García-Becerra, María Elena Bravo-Gómez, Austin J. Cooney
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:5593-5601
Tamoxifen is a selective estrogen receptor modulator widely used in oncology and reproductive endocrinology. In order to decrease its non-desirable effects and elucidate mechanisms of action, permanently charged tamoxifen derivatives (PCTDs) have bee
Autor:
Elizabeth Hernández-Gallegos, Euclides Avila-Chávez, Irais Ceja-Ochoa, Elizabeth Borja-Cacho, Rocío García-Becerra, Elías Ahumada, Claudia Rivera-Guevara, Juan C. Escamilla, David Barrera, Cindy Sharon Ortiz, Eunice Vera, Armando Gamboa-Domínguez, M. Uribe-Ramírez, Andrea De Vizcaya-Ruiz, Iván Restrepo-Angulo, Milena Saqui-Salces, David Ordaz-Rosado, Ethel García-Latorre, Ignacio Camacho-Arroyo, Elizabeth Alvarez-Rios, Angélica Morales, Patricio Gariglio, Luz C. Sánchez-Peña, Janet Murbartián, Rodolfo Ocadiz-Delgado, Javier Camacho, Fernando Larrea, Lorenza Díaz, Enrique García-Villa
Publikováno v:
Cancer Research. 69:3300-3307
Ether-à-go-go-1 (Eag1) potassium channels are potential tools for detection and therapy of numerous cancers. Here, we show human Eag1 (hEag1) regulation by cancer-associated factors. We studied hEag1 gene expression and its regulation by estradiol,