Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Claudia R. Vianna"'
Autor:
Gloria Ursino, Giorgio Ramadori, Anna Höfler, Soline Odouard, Pryscila D. S. Teixeira, Florian Visentin, Christelle Veyrat-Durebex, Giulia Lucibello, Raquel Firnkes, Serena Ricci, Claudia R. Vianna, Lin Jia, Mirjam Dirlewanger, Philippe Klee, Joel K. Elmquist, Johannes Roth, Thomas Vogl, Valérie M. Schwitzgebel, François R. Jornayvaz, Andreas Boland, Roberto Coppari
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Excess ketogenesis can lead to ketoacidosis, a serious complication in patients with diabetes. Here the authors report an insulin independent pathway, the hepatic nonparenchymal S100A9-TLR4-mTORC1 axis, that is able to normalize diabetic ketogenesis
Externí odkaz:
https://doaj.org/article/8ed9f595195e400f85d854d78ace7d95
Autor:
Eun-Seon Yoo, Li Li, Lin Jia, Caleb C. Lord, Charlotte E. Lee, Shari G. Birnbaum, Claudia R. Vianna, Eric D. Berglund, Kathryn A. Cunningham, Yong Xu, Jong-Woo Sohn, Chen Liu
Publikováno v:
Cell Reports, Vol 37, Iss 7, Pp 109997- (2021)
Summary: The anorexigenic effect of serotonergic compounds has largely been attributed to activation of serotonin 2C receptors (Htr2cs). Using mouse genetic models in which Htr2c can be selectively deleted or restored (in Htr2c-null mice), we investi
Externí odkaz:
https://doaj.org/article/35dc83b9b582460d887dc765f85d34a0
Autor:
Eun-Seon, Yoo, Li, Li, Lin, Jia, Caleb C, Lord, Charlotte E, Lee, Shari G, Birnbaum, Claudia R, Vianna, Eric D, Berglund, Kathryn A, Cunningham, Yong, Xu, Jong-Woo, Sohn, Chen, Liu
Publikováno v:
Cell reports
SUMMARY The anorexigenic effect of serotonergic compounds has largely been attributed to activation of serotonin 2C receptors (Htr2cs). Using mouse genetic models in which Htr2c can be selectively deleted or restored (in Htr2c-null mice), we investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4c74b88799d5c2c6769a05193b310d3
https://pubmed.ncbi.nlm.nih.gov/34788630
https://pubmed.ncbi.nlm.nih.gov/34788630
Autor:
Yong Xu, Jong Woo Sohn, Kathryn A. Cunningham, Claudia R. Vianna, Chen Liu, Caleb C. Lord, Eun-Seon Yoo, Charlotte E. Lee, Lin Jia, Eric D. Berglund, Li Li, Shari G. Birnbaum
Publikováno v:
Cell Reports, Vol 37, Iss 7, Pp 109997-(2021)
Summary: The anorexigenic effect of serotonergic compounds has largely been attributed to activation of serotonin 2C receptors (Htr2cs). Using mouse genetic models in which Htr2c can be selectively deleted or restored (in Htr2c-null mice), we investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e10c2704bd2b71f5cb960e3bfc9704
https://doi.org/10.1016/j.celrep.2021.109997
https://doi.org/10.1016/j.celrep.2021.109997
Autor:
Claudia R. Vianna, Carlos M. Castorena, Nathan P. Metzger, Jeffrey M. Zigman, Joel K. Elmquist, Prasanna Vijayaraghavan, Sherri Osborne-Lawrence, Bharath K. Mani, Charlotte E. Lee
Publikováno v:
Neuroscience
Ghrelin administration increases food intake, body weight (BW), adiposity, and blood glucose. In contrast, although mouse models lacking ghrelin or its receptor (Growth Hormone Secretagogue Receptor (GHSR)) exhibit life-threatening hypoglycemia in st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c3b66936f57da3fdc463d73e51d5be
https://pubmed.ncbi.nlm.nih.gov/31520709
https://pubmed.ncbi.nlm.nih.gov/31520709
Autor:
Jae Geun Kim, Pasko Rakic, Tamas L. Horvath, Francisco Hernandez-Nuno, Xiao-Bing Gao, Luis Varela, Sabrina Diano, Joel K. Elmquist, Stephanie E. Simonds, Claudia R. Vianna, Carlos M. Castorena, Yury M. Morozov, Klara Szigeti-Buck, Michael A. Cowley, Ingo Bechmann, Marcelo O. Dietrich, Jung Dae Kim, Marco Koch
Publikováno v:
Nature. 519:45-50
Hypothalamic pro-opiomelanocortin (POMC) neurons promote satiety. Cannabinoid receptor 1 (CB1R) is critical for the central regulation of food intake. Here we test whether CB1R-controlled feeding in sated mice is paralleled by decreased activity of P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cfb11ea73799588ff2d4df2007b96e4
https://doi.org/10.1038/nature14260
https://doi.org/10.1038/nature14260
Autor:
Claudia R. Vianna, Lauren Gautron, Stephanie Pierpont, Kyriakos D. Economides, Jari Rossi, Michael Scott, Jose Donato, Joel K. Elmquist, Carol F. Elias
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
The cannabinoid receptor 1 (CB(1)R) is required for body weight homeostasis and normal gastrointestinal motility. However, the specific cell types expressing CB(1)R that regulate these physiological functions are unknown. CB(1)R is widely expressed,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d12a5aed70c881db9fbf90d591772f03
https://doi.org/10.1523/jneurosci.4507-11.2012
https://doi.org/10.1523/jneurosci.4507-11.2012
Publikováno v:
Endocrinology. 151:5415-5427
Studies have indicated that the neurotransmitter nitric oxide (NO) mediates leptin’s effects in the neuroendocrine reproductive axis. However, the neurons involved in these effects and their regulation by leptin is still unknown. We aimed to determ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e28d43ce772431bf4e5b410327d279a6
https://doi.org/10.1210/en.2010-0651
https://doi.org/10.1210/en.2010-0651
Autor:
Mario Perello, Teppei Fujikawa, Giorgio Ramadori, Jason G. Anderson, Claudia R. Vianna, Raul Mostoslavsky, Ronald C. Stuart, Donald A. Morgan, Roberto Coppari, Kamal Rahmouni, Eduardo A. Nillni, Makoto Fukuda
Publikováno v:
Cell Metabolism. 12(1):78-87
Summary Feeding on high-calorie (HC) diets induces serious metabolic imbalances, including obesity. Understanding the mechanisms against excessive body weight gain is critical for developing effective antiobesity strategies. Here we show that lack of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d886e798bea5d3e4ea36246ea5e24e4b
Autor:
Claudia R. Vianna, Laurent Gautron, Giorgio Ramadori, Roberto Coppari, Joel K. Elmquist, Teppei Fujikawa
Publikováno v:
Endocrinology. 150:5326-5333
Resveratrol is a natural polyphenolic compound that activates nicotinamide adenosine dinucleotide-dependent deacetylase SIRT1. Resveratrol has recently been shown to exert potent antidiabetic actions when orally delivered to animal models of type 2 d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8228ab6a272f16e02df76483545356ef
https://doi.org/10.1210/en.2009-0528
https://doi.org/10.1210/en.2009-0528