Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Claudia R. Ruprecht"'
Autor:
Andreas Schweizer, Peter Rusert, Livia Berlinger, Claudia R Ruprecht, Axel Mann, Stéphanie Corthésy, Stuart G Turville, Meropi Aravantinou, Marek Fischer, Melissa Robbiani, Patrick Amstutz, Alexandra Trkola
Publikováno v:
PLoS Pathogens, Vol 4, Iss 7, p e1000109 (2008)
Here, we describe the generation of a novel type of HIV entry inhibitor using the recently developed Designed Ankyrin Repeat Protein (DARPin) technology. DARPin proteins specific for human CD4 were selected from a DARPin DNA library using ribosome di
Externí odkaz:
https://doaj.org/article/63f2e46f9bed439bb295b004f6d2249c
Autor:
Claudia R. Ruprecht, Livia Berlinger, Axel M Mann, Alexandra Trkola, Peter Rusert, Lucy Reynell, Anders Krarup, Oliver F. Brandenberg, Huldrych F. Günthard, Roland R. Regoes, Irene A Abela
Publikováno v:
The Journal of Experimental Medicine
The Journal of experimental medicine
The Journal of experimental medicine
Antibody-mediated gp120 shedding and HIV neutralization exhibit similar kinetics and thermodynamic requirements.
Interference with virus entry is known to be the principle mechanism of HIV neutralization by antibodies, including 2F5 and 4E10, wh
Interference with virus entry is known to be the principle mechanism of HIV neutralization by antibodies, including 2F5 and 4E10, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::013e2eefd0b6bc18cbd0fd8fda04fa41
http://europepmc.org/articles/PMC3058584
http://europepmc.org/articles/PMC3058584
Autor:
Antonio Lanzavecchia, Elisabetta Traggiai, Nadia L. Bernasconi, Davide Corti, Claudia R. Ruprecht, Federica Sallusto
Publikováno v:
Immunological Reviews
Summary: The work of our laboratory has focused on the study of human memory B cells. Using an in vitro approach we dissected the triggering requirements of B cells and unveiled a distinct role for TLRs in the activation of naive versus memory B cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7467f5de5f5a8785388c1c0729e79c0
https://doi.org/10.1111/j.0105-2896.2006.00403.x
https://doi.org/10.1111/j.0105-2896.2006.00403.x
Autor:
Robert A, Rasmussen, Helena, Ong, Christian, Kittel, Claudia R, Ruprecht, Flavia, Ferrantelli, Shiu-Lok, Hu, Patricia, Polacino, Patricia, Policano, Jennifer, McKenna, Jane, Moon, Bruce, Travis, Ruth M, Ruprecht
Publikováno v:
Vaccine. 24:2324-2332
The induction of both cellular and humoral immunity is an important goal for vaccine development against HIV. As a step towards the development of an efficacious vaccine against HIV clade C, the world's most prevalent strain, a combination DNA prime/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abac7b14f6af96ac1cdb9fbdc963576b
https://doi.org/10.1016/j.vaccine.2005.11.063
https://doi.org/10.1016/j.vaccine.2005.11.063
Autor:
Andrea Gregorio, Francesca Ferlito, Antonio Lanzavecchia, Marco Gattorno, Federica Sallusto, Claudia R. Ruprecht, Alberto Martini
Publikováno v:
The Journal of Experimental Medicine
A better understanding of the role of CD4+CD25+ regulatory T cells in disease pathogenesis should follow from the discovery of reliable markers capable of discriminating regulatory from activated T cells. We report that the CD4+CD25+ population in sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0678eb315a7db7b83747d566ce3a9f46
https://doi.org/10.1084/jem.20050085
https://doi.org/10.1084/jem.20050085
Autor:
Christine Leemann, Alexandra Trkola, B. Hirschel, Beda Joos, Amalio Telenti, Huldrych F. Günthard, Herbert Kuster, Sebastian Bonhoeffer, Claudia R. Ruprecht, Rainer Weber
Publikováno v:
Journal of Virology, Vol. 77, No 24 (2003) pp. 13146-13155
Human immunodeficiency virus type 1 (HIV-1) isolates from 20 chronically infected patients who participated in a structured treatment interruption (STI) trial were studied to determine whether viral fitness influences reestablishment of viremia. Viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c67fd9b5fa35aa6308bfec95cba3052
https://doi.org/10.1128/jvi.77.24.13146-13155.2003
https://doi.org/10.1128/jvi.77.24.13146-13155.2003
Publikováno v:
Retrovirology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cce03dd2f2517338f6167abb14572c3
https://doi.org/10.1186/1742-4690-6-s3-p65
https://doi.org/10.1186/1742-4690-6-s3-p65
Autor:
Meropi Aravantinou, Livia Berlinger, Stuart Turville, Stéphanie Corthésy, Marek Fischer, Claudia R. Ruprecht, Melissa Robbiani, Andreas Schweizer, Axel M Mann, Peter Rusert, Alexandra Trkola, Patrick Amstutz
Publikováno v:
PLoS Pathogens, Vol 4, Iss 7, p e1000109 (2008)
PLoS Pathogens
PLoS Pathogens
Here, we describe the generation of a novel type of HIV entry inhibitor using the recently developed Designed Ankyrin Repeat Protein (DARPin) technology. DARPin proteins specific for human CD4 were selected from a DARPin DNA library using ribosome di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f24ba0caaa0af8956f11c6cc8f4a0fa
https://www.zora.uzh.ch/id/eprint/8137/
https://www.zora.uzh.ch/id/eprint/8137/
Autor:
Helena Ong, C. M. McCann, Elizabeth Strobert, Weidong Xu, James G. Else, Robert A. Rasmussen, E. Shai-Kobiler, L. M. Goins, Ricky D. Grisson, Saied Mirshahidi, W. E. Secor, Harold M. McClure, Charles E. Wood, Claudia R. Ruprecht, Agnès-Laurence Chenine, P.-L. Li, Hong Zhang, James B. Whitney, Chipeppo Kankasa, Ruijiang Song, Tao Wang, Ruth M. Ruprecht
Publikováno v:
Journal of virology. 80(17)
Human immunodeficiency virus type 1 (HIV-1) clade C causes >50% of all HIV infections worldwide, and an estimated 90% of all transmissions occur mucosally with R5 strains. A pathogenic R5 simian-human immunodeficiency virus (SHIV) encoding HIV clade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d12e36b2674b84decf58154a6cefc2
https://pubmed.ncbi.nlm.nih.gov/16912320
https://pubmed.ncbi.nlm.nih.gov/16912320
Publikováno v:
European journal of immunology. 36(4)
According to the current model, naive B cell activation is dependent on the sequential integration of two signals: B cell receptor (BCR) cross-linking by antigen, followed by cognate interaction with helper T cells through an immunological synapse. U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a261226804385e9b32a9b5632edf704d
https://pubmed.ncbi.nlm.nih.gov/16572389
https://pubmed.ncbi.nlm.nih.gov/16572389