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Autor:
Corinne E. Griguer, Victor M. Darley-Usmar, Anne R. Diers, Praveen K. Vayalil, Aimee Landar, Claudia R. Olivia, Danny R. Welch, Douglas R. Hurst
Publikováno v:
Cancer Research. 73:1864-1864
Solid tumors are characterized by regions of low oxygen tension, which play a central role in tumor progression and resistance to therapy. The major organelle affected by reduced oxygen tension is the mitochondrion, which has to functionally adapt to