Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Claudia Pfander"'
Autor:
Claudia Pfander, Johanna Bischof, Marianna Childress-Poli, Antje Keppler, Alessandra Viale, Silvio Aime, John E. Eriksson
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103800- (2022)
Externí odkaz:
https://doaj.org/article/9d508d30ebba427f814c525fa0cd63fe
Autor:
Katrin Volkmann, Claudia Pfander, Charlotte Burstroem, Malika Ahras, David Goulding, Julian C Rayner, Friedrich Frischknecht, Oliver Billker, Mathieu Brochet
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41409 (2012)
Alveolins, or inner membrane complex (IMC) proteins, are components of the subpellicular network that forms a structural part of the pellicle of malaria parasites. In Plasmodium berghei, deletions of three alveolins, IMC1a, b, and h, each resulted in
Externí odkaz:
https://doaj.org/article/92c4506048e24dc9a90e810cff6840f1
Autor:
Ana Rita Gomes, Kirsten Dundas, Lia Chappell, Jyoti S. Choudhary, Katarzyna Modrzynska, Lu Yu, Catherine Suarez, David Goulding, Oliver Billker, Claudia Pfander, Julian C. Rayner
Publikováno v:
Cell Host & Microbe
Summary A family of apicomplexa-specific proteins containing AP2 DNA-binding domains (ApiAP2s) was identified in malaria parasites. This family includes sequence-specific transcription factors that are key regulators of development. However, function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81451a1ddb755bf88eff503f09a7cf2a
https://doi.org/10.1016/j.chom.2016.12.003
https://doi.org/10.1016/j.chom.2016.12.003
Autor:
Claudia Pfander, Kayode K. Ojo, David J. Leibly, Dustin J. Maly, Henning Mann, Charlotte Burstroem, Ryan C. Murphy, Mark Kennedy, Cassie M. Bryan, Steven M. Johnson, Ethan A. Merritt, Stephen N. Hewitt, Natascha Mueller, Oliver Billker, Molly C. Reid, Anna M. W. Fox, Eric T. Larson, Christophe L. M. J. Verlinde, Wesley C. Van Voorhis, Stefan H. I. Kappe
Publikováno v:
Journal of Clinical Investigation; Vol 122
Effective control and eradication of malaria will require new tools to prevent transmission. Current antimalarial therapies targeting the asexual stage of Plasmodium do not prevent transmission of circulating gametocytes from infected humans to mosqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d47a0f0d75061cef960f3c330d4841
Autor:
Arnab Pain, Claudia Pfander, Michael A. Quail, Frank Schwach, William C. Skarnes, Katrin Volkmann, Julian C. Rayner, Barry Rosen, Mathieu Brochet, Thomas D. Otto, Oliver Billker, Burcu Anar
Publikováno v:
Nature Methods; Vol 8
Nature methods
Nature methods
In malaria parasites, the systematic experimental validation of drug and vaccine targets by reverse genetics is constrained by the inefficiency of homologous recombination and by the difficulty of manipulating adenine and thymine (A+T)-rich DNA of mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0793b1b04bd39682800ef96b025c8c7c
https://doi.org/10.1038/nmeth.1742
https://doi.org/10.1038/nmeth.1742
Autor:
Michael A. Quail, Ana Rita Gomes, Julian C. Rayner, Claudia Pfander, Gareth Girling, Katarzyna Modrzynska, Burcu Anar, Colin Herd, Oliver Billker, Frank Schwach, Ellen Bushell
Publikováno v:
Cell Host & Microbe
Summary The genome-wide identification of gene functions in malaria parasites is hampered by a lack of reverse genetic screening methods. We present a large-scale resource of barcoded vectors with long homology arms for effective modification of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1bcdc83a9bfe3aa88614384cecce3e4
https://pubmed.ncbi.nlm.nih.gov/25732065
https://pubmed.ncbi.nlm.nih.gov/25732065
Autor:
David Goulding, Mathieu Brochet, Mandy Sanders, Gary Vanderlaan, Jimin Pei, Frank Schwach, Claudia Pfander, William J. Snell, Nick V. Grishin, Oliver Billker, Paul A. Lefebvre, Ellen Bushell, Thomas D. Otto, Jue Ning
Publikováno v:
Genes and Development, Vol. 27, No 10 (2013) pp. 1198-1215
Fertilization is a crucial yet poorly characterized event in eukaryotes. Our previous discovery that the broadly conserved protein HAP2 (GCS1) functioned in gamete membrane fusion in the unicellular green alga Chlamydomonas and the malaria pathogen P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c67f82c9641cc8453a1d18416c0c467
https://eprints.gla.ac.uk/148019/1/148019.pdf
https://eprints.gla.ac.uk/148019/1/148019.pdf
Autor:
Katie R. Hughes, Katarzyna Modrzynska, Ellen Bushell, Abhinav Sinha, Nicholas J. Dickens, Thomas D. Otto, Björn F.C. Kafsack, April E. Williams, Agnieszka A. Religa, Andrew P. Waters, Manuel Llinás, Matthew Berriman, Anne Graham, Rachael Cameron, Oliver Billker, Claudia Pfander
Publikováno v:
Nature
Commitment to and completion of sexual development are essential for malaria parasites (protists of the genus Plasmodium) to be transmitted through mosquitoes. The molecular mechanism(s) responsible for commitment have been hitherto unknown. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3af2f735046585040df88eebd557bd
https://pubmed.ncbi.nlm.nih.gov/24608336
https://pubmed.ncbi.nlm.nih.gov/24608336
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 923
DNA of Plasmodium berghei is difficult to manipulate in Escherichia coli by conventional restriction and ligation methods due to its high content of adenine and thymine (AT) nucleotides. This limits our ability to clone large genes and to generate co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71c9184f22e926d24a92c7a807781045
https://pubmed.ncbi.nlm.nih.gov/22990774
https://pubmed.ncbi.nlm.nih.gov/22990774
Publikováno v:
Methods in Molecular Biology ISBN: 9781627030250
DNA of Plasmodium berghei is difficult to manipulate in Escherichia coli by conventional restriction and ligation methods due to its high content of adenine and thymine (AT) nucleotides. This limit ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31d7748205cecc1ca8b3d498f352190f
https://doi.org/10.1007/978-1-62703-026-7_8
https://doi.org/10.1007/978-1-62703-026-7_8