Efficacy of vildagliptin for prevention of postpartum diabetes in women with a recent history of insulin-requiring gestational diabetes: A phase II, randomized, double-blind, placebo-controlled study

Autor: Sandra Hummel, Andreas Beyerlein, Markus Pfirrmann, Anna Hofelich, Daniela Much, Susanne Hivner, Melanie Bunk, Melanie Herbst, Claudia Peplow, Markus Walter, Denise Kohn, Nadine Hummel, Jürgen Kratzsch, Michael Hummel, Martin Füchtenbusch, Joerg Hasford, Anette-G. Ziegler, Heike Börschmann, Sophia Ebe, Eleni Giannopoulou, Minna Harsunen, Veronika Hofbauer, Andrea Schuppenies, Maike Wallner, David Wiesenäcker, Stephanie Zillmer, Lorenz Lachmann, Rüdiger Landgraf, Karl-Theo Maria Schneider, Elisabeth André, Viktoria Janke, Ezio Bonifacio

Publikováno v: Molecular Metabolism, Vol 9, Iss , Pp 168-175 (2018)

Objective: Women with insulin-requiring gestational diabetes mellitus (GDM) are at high risk of developing diabetes within a few years postpartum. We implemented this phase II study to test the hypothesis that vildagliptin, a dipeptidyl peptidase-4 i

Externí odkaz: https://doaj.org/article/635c2bfed81846888df968d30e3d0269

Effects of Gluten Intake on Risk of Celiac Disease: A Case-Control Study on a Swedish Birth Cohort

Autor: Carin Andrén Aronsson, Hye-Seung Lee, Sibylle Koletzko, Ulla Uusitalo, Jimin Yang, Suvi M. Virtanen, Edwin Liu, Åke Lernmark, Jill M. Norris, Daniel Agardh, Marian Rewers, Kimberly Bautista, Judith Baxter, Ruth Bedoy, Daniel Felipe-Morales, Brigitte I. Frohnert, Patricia Gesualdo, Michelle Hoffman, Rachel Karban, Jill Norris, Adela Samper-Imaz, Andrea Steck, Kathleen Waugh, Hali Wright, Jin-Xiong She, Desmond Schatz, Diane Hopkins, Leigh Steed, Jamie Thomas, Janey Adams, Katherine Silvis, Michael Haller, Melissa Gardiner, Richard McIndoe, Ashok Sharma, Joshua Williams, Gabriela Foghis, Stephen W. Anderson, Richard Robinson, Anette G. Ziegler, Andreas Beyerlein, Ezio Bonifacio, Michael Hummel, Sandra Hummel, Kristina Foterek, Mathilde Kersting, Annette Knopff, Claudia Peplow, Roswith Roth, Joanna Stock, Elisabeth Strauss, Katharina Warncke, Christiane Winkler, Jorma Toppari, Olli G. Simell, Annika Adamsson, Heikki Hyöty, Jorma Ilonen, Sanna Jokipuu, Tiina Kallio, Miia Kähönen, Mikael Knip, Annika Koivu, Mirva Koreasalo, Kalle Kurppa, Maria Lönnrot, Elina Mäntymäki, Katja Multasuo, Juha Mykkänen, Tiina Niininen, Mia Nyblom, Petra Rajala, Jenna Rautanen, Anne Riikonen, Minna Romo, Satu Simell, Tuula Simell, Ville Simell, Maija Sjöberg, Aino Stenius, Maria Särmä, Sini Vainionpää, Eeva Varjonen, Riitta Veijola, Mari Vähä-Mäkilä, Mari Åkerlund, Maria Ask, Jenny Bremer, Ulla-Marie Carlsson, Corrado Cilio, Emelie Ericson-Hallström, Lina Fransson, Thomas Gard, Joanna Gerardsson, Rasmus Bennet, Monica Hansen, Gertie Hansson, Cecilia Harmby, Susanne Hyberg, Fredrik Johansen, Berglind Jonasdottir, Helena Elding Larsson, Sigrid Lenrick Forss, Markus Lundgren, Maria Månsson-Martinez, Maria Markan, Jessica Melin, Zeliha Mestan, Kobra Rahmati, Anita Ramelius, Anna Rosenquist, Falastin Salami, Sara Sibthorpe, Birgitta Sjöberg, Ulrica Swartling, Evelyn Tekum Amboh, Erika Trulsson, Carina Törn, Anne Wallin, Åsa Wimar, Sofie Åberg, William A. Hagopian, Michael Killian, Claire Cowen Crouch, Jennifer Skidmore, Stephen Ayres, Kayleen Dunson, Rachel Hervey, Corbin Johnson, Rachel Lyons, Arlene Meyer, Denise Mulenga, Elizabeth Scott, Joshua Stabbert, Alexander Tarr, Morgan Uland, John Willis, Dorothy Becker, Margaret Franciscus, MaryEllen Dalmagro-Elias Smith, Ashi Daftary, Mary Beth Klein, Chrystal Yates, Jeffrey P. Krischer, Michael Abbondondolo, Sarah Austin-Gonzalez, Sandra Baethke, Rasheedah Brown, Brant Burkhardt, Martha Butterworth, Joanna Clasen, David Cuthbertson, Christopher Eberhard, Steven Fiske, Dena Garcia, Jennifer Garmeson, Veena Gowda, Kathleen Heyman, Francisco Perez Laras, Shu Liu, Xiang Liu, Kristian Lynch, Jamie Malloy, Cristina McCarthy, Wendy McLeod, Steven Meulemans, Chris Shaffer, Laura Smith, Susan Smith, Noah Sulman, Roy Tamura, Kendra Vehik, Ponni Vijayakandipan, Keith Wood, Lori Ballard, David Hadley, Beena Akolkar, Kasia Bourcier, Thomas Briese, Suzanne Bennett Johnson, Eric Triplett

Publikováno v: Clin. Gastroenterol. Hepatol. 14, 403-409 (2016)
Clinical Gastroenterology and Hepatology; 14(3), pp 403-409 (2016)

BACKGROUND & AIMS: It is not clear how intake of gluten during infancy affects subsequent risk of celiac disease. We investigated whether gluten intake before 2 years of age increases risk for celiac disease in genetically susceptible children. METHO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538cc2d41c6440f5df943a9b42dbe017
https://pubmed.ncbi.nlm.nih.gov/26681485

Effects of high-dose oral insulin on immune responses in children at high risk for type 1 diabetes: The Pre-POINT randomized clinical trial

Autor: Ezio, Bonifacio, Anette-G, Ziegler, Georgeanna, Klingensmith, Edith, Schober, Polly J, Bingley, Marietta, Rottenkolber, Anke, Theil, Anne, Eugster, Ramona, Puff, Claudia, Peplow, Florian, Buettner, Karin, Lange, Jörg, Hasford, Peter, Achenbach, Nicola, Farthing

Publikováno v: JAMA 313, 1541-1549 (2015)

Importance: Exposing the oral mucosa to antigen may stimulate immune tolerance. It is unknown whether treatment with oral insulin can induce a tolerogenic immune response in children genetically susceptible to type 1 diabetes. Objective: To assess th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec6917165400fd690c99d6660dbfda7
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=44455