Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Claudia Peitzsch"'
Autor:
Iñaki Schniewind, Maria José Besso, Sebastian Klicker, Franziska Maria Schwarz, Wahyu Wijaya Hadiwikarta, Susan Richter, Steffen Löck, Annett Linge, Mechthild Krause, Anna Dubrovska, Michael Baumann, Ina Kurth, Claudia Peitzsch
Publikováno v:
Cancers, Vol 16, Iss 4, p 730 (2024)
(1) Background: The sensitivity of head and neck squamous cell carcinoma (HNSCC) to ionizing radiation, among others, is determined by the number of cells with high clonogenic potential and stem-like features. These cellular characteristics are dynam
Externí odkaz:
https://doaj.org/article/83e3524b7dc14bd592f79225adf307d4
Autor:
Felix Meyer, Anna Maria Engel, Ann Kristin Krause, Tim Wagner, Lena Poole, Anna Dubrovska, Claudia Peitzsch, Kai Rothkamm, Cordula Petersen, Kerstin Borgmann
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Cancer stem cells (CSCs) are a major cause of tumor therapy failure. This is mainly attributed to increased DNA repair capacity and immune escape. Recent studies have shown that functional DNA repair via homologous recombination (HR) prevents radiati
Externí odkaz:
https://doaj.org/article/fdb2d8df0fc941a283280939b46c8565
Autor:
Dinah Linke, Lukas Donix, Claudia Peitzsch, Holger H. H. Erb, Anna Dubrovska, Manuel Pfeifer, Christian Thomas, Susanne Fuessel, Kati Erdmann
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 666 (2022)
Docetaxel (DTX) is a mainstay in the treatment of metastatic prostate cancer. Failure of DTX therapy is often associated with multidrug resistance caused by overexpression of efflux membrane transporters of the ABC family such as the glycoprotein ABC
Externí odkaz:
https://doaj.org/article/e6f8e7868a164829a0c4b73361f74359
Autor:
Daria Klusa, Fabian Lohaus, Giulia Furesi, Martina Rauner, Martina Benešová, Mechthild Krause, Ina Kurth, Claudia Peitzsch
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Radiotherapy and surgery are curative treatment options for localized prostate cancer (PCa) with a 5-year survival rate of nearly 100%. Once PCa cells spread into distant organs, such as bone, the overall survival rate of patients drops dramatically.
Externí odkaz:
https://doaj.org/article/86f4222e0ee742fba57571ebccea3724
Autor:
Michael Seifert, Claudia Peitzsch, Ielizaveta Gorodetska, Caroline Börner, Barbara Klink, Anna Dubrovska
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 11, p e1007460 (2019)
Radiation therapy is an important and effective treatment option for prostate cancer, but high-risk patients are prone to relapse due to radioresistance of cancer cells. Molecular mechanisms that contribute to radioresistance are not fully understood
Externí odkaz:
https://doaj.org/article/72ad028e987d4d9b8b5c4360841a115c
Autor:
Lina Lüttich, María José Besso, Stephan Heiden, Lydia Koi, Michael Baumann, Mechthild Krause, Anna Dubrovska, Annett Linge, Ina Kurth, Claudia Peitzsch
Publikováno v:
Cancers, Vol 13, Iss 8, p 1865 (2021)
The receptor tyrosine kinase c-MET activates intracellular signaling and induces cell proliferation, epithelial-to-mesenchymal-transition and migration. Within the present study, we validated the prognostic value of c-MET in patients with head and ne
Externí odkaz:
https://doaj.org/article/f413cb176072476cb94a50e626a21233
Autor:
Maik Friedrich, Karolin Wiedemann, Kristin Reiche, Sven-Holger Puppel, Gabriele Pfeifer, Ivonne Zipfel, Stefanie Binder, Ulrike Köhl, Gerd A. Müller, Kurt Engeland, Achim Aigner, Susanne Füssel, Michael Fröhner, Claudia Peitzsch, Anna Dubrovska, Michael Rade, Sabina Christ, Stephan Schreiber, Jörg Hackermüller, Jörg Lehmann, Marieta I. Toma, Michael H. Muders, Ulrich Sommer, Gustavo B. Baretton, Manfred Wirth, Friedemann Horn
Publikováno v:
Cancers, Vol 12, Iss 5, p 1122 (2020)
In search of new biomarkers suitable for the diagnosis and treatment of prostate cancer, genome-wide transcriptome sequencing was carried out with tissue specimens from 40 prostate cancer (PCa) and 8 benign prostate hyperplasia patients. We identifie
Externí odkaz:
https://doaj.org/article/38b05cd247be42b0aab2a78f192acbbe
Autor:
Nastassja Terraneo, Francis Jacob, Claudia Peitzsch, Anna Dubrovska, Christiane Krudewig, Yen-Lin Huang, Viola Heinzelmann-Schwarz, Roger Schibli, Martin Béhé, Jürgen Grünberg
Publikováno v:
Cancers, Vol 12, Iss 1, p 217 (2020)
Many solid tumors, including ovarian cancer, contain small populations of cancer stem cells (CSCs). These cells are usually resistant against conventional cancer therapies and play a role in disease recurrence. We demonstrated that the L1 cell adhesi
Externí odkaz:
https://doaj.org/article/3a05e9c7457442ba8e3d5f4441697861
Autor:
Claudia Peitzsch, Jacqueline Nathansen, Sebastian I. Schniewind, Franziska Schwarz, Anna Dubrovska
Publikováno v:
Cancers, Vol 11, Iss 5, p 616 (2019)
Head and neck squamous cell carcinoma (HNSCC) is the sixth most commonly diagnosed cancer worldwide. Despite advances in the treatment management, locally advanced disease has a poor prognosis, with a 5-year survival rate of approximately 50%. The gr
Externí odkaz:
https://doaj.org/article/c9c37732c67544c3918f1d9991f9aa25
Autor:
Daria Klusa, Fabian Lohaus, Andre Franken, Marian Baumbach, Monica Cojoc, Paul Dowling, Annett Linge, Anne Offermann, Steffen Löck, Dejan Hušman, Mahdi Rivandi, Bernhard Polzer, Vera Freytag, Tobias Lange, Hans Neubauer, Michael Kücken, Sven Perner, Tobias Hölscher, Anna Dubrovska, Mechthild Krause, Ina Kurth, Michael Baumann, Claudia Peitzsch
Publikováno v:
International Journal of Cancer. 152:2639-2654