Zobrazeno 1 - 10 of 110 pro vyhledávání: '"Claudia Peitzsch"'
1
Akademický článek
Efficient DNA Repair Mitigates Replication Stress Resulting in Less Immunogenic Cytosolic DNA in Radioresistant Breast Cancer Stem Cells
Autor: Felix Meyer, Anna Maria Engel, Ann Kristin Krause, Tim Wagner, Lena Poole, Anna Dubrovska, Claudia Peitzsch, Kai Rothkamm, Cordula Petersen, Kerstin Borgmann
Publikováno v: Frontiers in Immunology, Vol 13 (2022)
Cancer stem cells (CSCs) are a major cause of tumor therapy failure. This is mainly attributed to increased DNA repair capacity and immune escape. Recent studies have shown that functional DNA repair via homologous recombination (HR) prevents radiati
Externí odkaz: https://doaj.org/article/fdb2d8df0fc941a283280939b46c8565
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2
Akademický článek
Comprehensive Evaluation of Multiple Approaches Targeting ABCB1 to Resensitize Docetaxel-Resistant Prostate Cancer Cell Lines
Autor: Dinah Linke, Lukas Donix, Claudia Peitzsch, Holger H. H. Erb, Anna Dubrovska, Manuel Pfeifer, Christian Thomas, Susanne Fuessel, Kati Erdmann
Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 1, p 666 (2022)
Docetaxel (DTX) is a mainstay in the treatment of metastatic prostate cancer. Failure of DTX therapy is often associated with multidrug resistance caused by overexpression of efflux membrane transporters of the ABC family such as the glycoprotein ABC
Externí odkaz: https://doaj.org/article/e6f8e7868a164829a0c4b73361f74359
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4
Akademický článek
Metastatic Spread in Prostate Cancer Patients Influencing Radiotherapy Response
Autor: Daria Klusa, Fabian Lohaus, Giulia Furesi, Martina Rauner, Martina Benešová, Mechthild Krause, Ina Kurth, Claudia Peitzsch
Publikováno v: Frontiers in Oncology, Vol 10 (2021)
Radiotherapy and surgery are curative treatment options for localized prostate cancer (PCa) with a 5-year survival rate of nearly 100%. Once PCa cells spread into distant organs, such as bone, the overall survival rate of patients drops dramatically.
Externí odkaz: https://doaj.org/article/86f4222e0ee742fba57571ebccea3724
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5
Akademický článek
Network-based analysis of prostate cancer cell lines reveals novel marker gene candidates associated with radioresistance and patient relapse.
Autor: Michael Seifert, Claudia Peitzsch, Ielizaveta Gorodetska, Caroline Börner, Barbara Klink, Anna Dubrovska
Publikováno v: PLoS Computational Biology, Vol 15, Iss 11, p e1007460 (2019)
Radiation therapy is an important and effective treatment option for prostate cancer, but high-risk patients are prone to relapse due to radioresistance of cancer cells. Molecular mechanisms that contribute to radioresistance are not fully understood
Externí odkaz: https://doaj.org/article/72ad028e987d4d9b8b5c4360841a115c
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