Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Claudia P Figueiredo"'
Autor:
Ana C Vicente Santos, Francisca H Guedes-da-Silva, Carlos H Dumard, Vivian N S Ferreira, Igor P S da Costa, Ruana A Machado, Fernanda G Q Barros-Aragão, Rômulo L S Neris, Júlio S Dos-Santos, Iranaia Assunção-Miranda, Claudia P Figueiredo, André A Dias, Andre M O Gomes, Herbert L de Matos Guedes, Andrea C Oliveira, Jerson L Silva
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 11, p e0009907 (2021)
Zika virus (ZIKV) emerged as an important infectious disease agent in Brazil in 2016. Infection usually leads to mild symptoms, but severe congenital neurological disorders and Guillain-Barré syndrome have been reported following ZIKV exposure. Crea
Externí odkaz:
https://doaj.org/article/9a0c189268f04faf98a26350189d234f
Autor:
Julia R Clarke, Natalia M Lyra e Silva, Claudia P Figueiredo, Rudimar L Frozza, Jose H Ledo, Danielle Beckman, Carlos K Katashima, Daniela Razolli, Bruno M Carvalho, Renata Frazão, Marina A Silveira, Felipe C Ribeiro, Theresa R Bomfim, Fernanda S Neves, William L Klein, Rodrigo Medeiros, Frank M LaFerla, Jose B Carvalheira, Mario J Saad, Douglas P Munoz, Licio A Velloso, Sergio T Ferreira, Fernanda G De Felice
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 2, Pp 190-210 (2015)
Abstract Alzheimer's disease (AD) is associated with peripheral metabolic disorders. Clinical/epidemiological data indicate increased risk of diabetes in AD patients. Here, we show that intracerebroventricular infusion of AD‐associated Aβ oligomer
Externí odkaz:
https://doaj.org/article/bfe3876cdb4d49808c5c97e93ba78817
Autor:
Fabricia L. Fontes-Dantas, Gabriel G. Fernandes, Elisa G. Gutman, Emanuelle V. De Lima, Leticia S. Antonio, Mariana B. Hammerle, Hannah P. Mota-Araujo, Lilian C. Colodeti, Suzana M.B. Araújo, Gabrielle M. Froz, Talita N. da Silva, Larissa A. Duarte, Andreza L. Salvio, Karina L. Pires, Luciane A.A. Leon, Claudia Cristina F. Vasconcelos, Luciana Romão, Luiz Eduardo B. Savio, Jerson L. Silva, Robson da Costa, Julia R. Clarke, Andrea T. Da Poian, Soniza V. Alves-Leon, Giselle F. Passos, Claudia P. Figueiredo
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112189- (2023)
Summary: Cognitive dysfunction is often reported in patients with post-coronavirus disease 2019 (COVID-19) syndrome, but its underlying mechanisms are not completely understood. Evidence suggests that severe acute respiratory syndrome coronavirus 2 (
Externí odkaz:
https://doaj.org/article/fe134363e486421c960c5fd3b4c479bc
Autor:
Talita Nascimento da Silva, Emanuelle V. de Lima, Thaís Nogueira Barradas, Carla G. Testa, Paulo H.S. Picciani, Claudia P. Figueiredo, Flavia A. do Carmo, Julia R. Clarke
Publikováno v:
Materials Today Bio, Vol 18, Iss , Pp 100525- (2023)
Several human pathogens can cause long-lasting neurological damage. Despite the increasing clinical knowledge about these conditions, most still lack efficient therapeutic interventions. Gene therapy (GT) approaches comprise strategies to modify or a
Externí odkaz:
https://doaj.org/article/8fe72e0acfe140d6bd6891cc0b86b091
Akademický článek
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Autor:
Danilo Predes, Lorena A. Maia, Isadora Matias, Hannah Paola Mota Araujo, Carolina Soares, Fernanda G. Q. Barros-Aragão, Luiz F. S. Oliveira, Renata R. Reis, Nathalia G. Amado, Alessandro B. C. Simas, Fabio A. Mendes, Flávia C. A. Gomes, Claudia P. Figueiredo, Jose G. Abreu
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12078 (2022)
The Wnt/β-catenin signaling pathway dictates cell proliferation and differentiation during embryonic development and tissue homeostasis. Its deregulation is associated with many pathological conditions, including neurodegenerative disease, frequentl
Externí odkaz:
https://doaj.org/article/b6e7926c111541fdb55d182315a0acfc
Autor:
Ingrid Del Castilo, Arthur S. Neumann, Felipe S. Lemos, Marco A. De Bastiani, Felipe L. Oliveira, Eduardo R. Zimmer, Amanda M. Rêgo, Cristiane C. P. Hardoim, Luis Caetano M. Antunes, Flávio A. Lara, Claudia P. Figueiredo, Julia R. Clarke
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5583 (2022)
RoundUp® (RUp) is a comercial formulation containing glyphosate (N-(phosphono-methyl) glycine), and is the world’s leading wide-spectrum herbicide used in agriculture. Supporters of the broad use of glyphosate-based herbicides (GBH) claim they are
Externí odkaz:
https://doaj.org/article/180388f54b89451686bac1edafd03660
Autor:
Helen M. Melo, Gisele da S. Seixas da Silva, Marcella Ramos Sant’Ana, Camila Vieira Ligo Teixeira, Julia R. Clarke, Vivian S. Miya Coreixas, Bruno C. de Melo, Juliana T.S. Fortuna, Leticia Forny-Germano, José Henrique Ledo, Maíra S. Oliveira, Claudia P. Figueiredo, Raphaelle Pardossi-Piquard, Frédéric Checler, José María Delgado-García, Agnès Gruart, Licio A. Velloso, Marcio L.F. Balthazar, Dennys E. Cintra, Sergio T. Ferreira, Fernanda G. De Felice
Publikováno v:
Cell Reports, Vol 30, Iss 7, Pp 2180-2194.e8 (2020)
Summary: Obesity has been associated with cognitive decline, atrophy of brain regions related to learning and memory, and higher risk of developing dementia. However, the molecular mechanisms underlying these neurological alterations are still largel
Externí odkaz:
https://doaj.org/article/a8705f38283e423d9640c717a5d7ee14
Autor:
Fabricia L. Fontes-Dantas, Gabriel G. Fernandes, Elisa G. Gutman, Emanuelle V. De Lima, Leticia S. Antonio, Mariana B. Hammerle, Hannah P. Mota-Araujo, Lilian C. Colodeti, Suzana M. B. Araújo, Talita N. da Silva, Larissa A. Duarte, Andreza L. Salvio, Karina L. Pires, Luciane A. A. Leon, Claudia Cristina F. Vasconcelos, Luciana Romão, Luiz Eduardo B. Savio, Jerson L. Silva, Robson da Costa, Julia R. Clarke, Andrea T. Da Poian, Soniza V. Alves-Leon, Giselle F. Passos, Claudia P. Figueiredo
Cognitive dysfunction is often reported in post-COVID patients, but its underlying mechanisms remain unknown. While some evidence indicate that SARS-CoV-2 can reach and directly impact the brain, others suggest viral neuroinvasion as a rare event. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c0339e927cbaa9c7540b83589ff021e
https://doi.org/10.1101/2022.06.07.495149
https://doi.org/10.1101/2022.06.07.495149
Autor:
John G M, Mina, Rebecca L, Charlton, Edubiel, Alpizar-Sosa, Douglas O, Escrivani, Christopher, Brown, Amjed, Alqaisi, Maria Paula G, Borsodi, Claudia P, Figueiredo, Emanuelle V, de Lima, Emily A, Dickie, Wenbin, Wei, Robson, Coutinho-Silva, Andy, Merritt, Terry K, Smith, Michael P, Barrett, Bartira, Rossi-Bergmann, Paul W, Denny, Patrick G, Steel
Publikováno v:
ACS Infectious Diseases
Current chemotherapeutics for leishmaniasis have multiple deficiencies, and there is a need for new safe, efficacious, and affordable medicines. This study describes a successful drug repurposing approach that identifies the over-the-counter antihist