Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Claudia Neumann-Haefelin"'
Autor:
Hans-Paul Juretschke, Claudia Neumann-Haefelin, Frans A. van Nieuwenhoven, Marc van Bilsen, Ger J. van der Vusse, Dominik Linz, Anneleen Daniels, Chantal Munts, Thorsten Sadowski, Sven Ruf, Hartmut Rütten
Publikováno v:
European journal of heart failure, 14(2), 193-201. Wiley
Aims Type 2 diabetes mellitus (DM) leads to cardiac dysfunction irrespective of hypertension and coronary artery disease; this is called diabetic cardiomyopathy. Here, we investigated the severity of diabetic cardiomyopathy and myocardial remodelling
Autor:
Hans-Paul Juretschke, Ralf Elvert, Werner Kramer, Michaela Liebig, Guido Haschke, Andreas W. Herling, Claudia Neumann-Haefelin, Mark D. Black, Matthias Gossel, Jeremy Pratt
Publikováno v:
Obesity. 18:1952-1958
This is the first study to examine the effect of subchronic olanzapine (OLZ) on energy homeostasis in rats, covering all aspects of energy balance, including energy intake as metabolizable energy, storage, and expenditure. We further analyzed whether
Autor:
Johanna Kuhlmann, Hans-Paul Juretschke, Michael Roden, Anja Beha, Martin Gerl, Werner Kramer, Claudia Neumann-Haefelin, Ulrich Belz, Andreas W. Herling
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 290:E989-E997
Intramyocellular lipid content (IMCL) serves as a good biomarker of skeletal muscle insulin resistance (IR). However, intracellular fatty acid metabolites [malonyl-CoA, long-chain acyl-CoA (LCACoA)] rather than IMCL are considered to be responsible f
Autor:
Andreas W. Herling, Claudia Neumann-Haefelin, W. Kramer, Ulrich Belz, Johanna Kuhlmann, Hans-Paul Juretschke
Publikováno v:
Magnetic Resonance in Medicine. 53:1275-1282
Increased intramyocellular lipid (IMCL) content has been proposed as biomarker for insulin resistance (IR). An inverse correlation between IMCL and insulin sensitivity (IS) was found in nonathletic humans, whereas in animal models only a few validati
Autor:
Gabriele Biemer-Daub, Juergen Kalisch, Claudia Neumann-Haefelin, Werner Kramer, Johanna Kuhlmann, Matthias Gossel, Corinna Schoelch, Andreas W. Herling, Guenter Mueller, Hans-Paul Juretschke, Ulrich Belz
Publikováno v:
Diabetes. 53:1920-1926
Increased supply of fatty acids to muscle and liver is causally involved in the insulin resistance syndrome. Using a tissue microdialysis technique in Wistar and Zucker fatty (ZF) rats, we determined tissue glycerol levels as a marker of lipolysis in
Autor:
Claudia Neumann-Haefelin, Shakir Sarhan, Hans-Paul Juretschke, Juergen Kalisch, Petty Margaret, Joseph G Wettstein
Publikováno v:
European Journal of Pharmacology. 474:53-62
The neuroprotective activity of ACEA 1021 (5-nitro-6,7-dichloro-1,4-dihydro-2,3-quinoxalinedione; licostinel), a selective antagonist at the strychnine-insensitive glycine site associated with the NMDA receptor complex, has been investigated in vario
Autor:
Johanna Kuhlmann, Claudia Neumann-Haefelin, Hans-Paul Juretschke, Andreas W. Herling, Werner Kramer, Jürgen Kalisch, Elke Kleinschmidt, Ulrich Belz, Marion Stein
Publikováno v:
Diabetes. 52:138-144
Insulin resistance plays an important role in the pathogenesis of human type 2 diabetes. In humans, a negative correlation between insulin sensitivity and intramyocellular lipid (IMCL) content has been shown; thus, IMCL becomes a marker for insulin r
Autor:
Frank Pillekamp, Gerrit Brinker, Mathias Hoehn, Ulla Uhlenküken, Konstantin-Alexander Hossmann, Claudia Neumann-Haefelin
Publikováno v:
Stroke. 33:1392-1398
Background and Purpose — Thrombolytic treatment of stroke carries the risk of hemorrhagic transformation. Therefore, the potential of MRI for prediction of recombinant tissue plasminogen activator (rtPA)–induced bleeding is explored to identify p
Autor:
Barbara Vollmayr, Alexander Sartorius, Gabriele Ende, Claudia Neumann-Haefelin, Fritz A. Henn, Mathias Hoehn
Publikováno v:
NeuroReport. 14:2199-2201
Metabolic changes in the hippocampus formation can be investigated with in vivo magnetic resonance spectroscopy (MRS). Learned helplessness (LH) is a well validated animal model of depression which we established in Sprague-Dawley rats defining some
Autor:
Hans-Paul Juretschke, Gerl M, Claudia Neumann-Haefelin, Kilp S, W. Kramer, Andreas W. Herling
Publikováno v:
International journal of obesity (2005). 32(9)
The severity of obesity is often more determined by the distribution of fat depots rather than by body weight itself. Therefore, the effect of rimonabant on fat distribution pattern was investigated in female candy-fed Wistar rats. Female Wistar rats