Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Claudia N. Paiva"'
Autor:
Rafael Cardoso Maciel Costa Silva, Luis Batista Tan, Andreza Moreira dos Santos Gama, Nuccia Nicole Theodoro De Cicco, Nicolas S. Merle, Lubka T. Roumenina, Yi Zhang, Gregory C. Henderson, André N.A. Gonçalves, Georgia C. Atella, João Trindade Marques, Leonardo Holanda Travassos, Claudia N. Paiva, Bénédicte Manoury, Marcelo Torres Bozza
Publikováno v:
Advances in Redox Research, Vol 8, Iss , Pp 100069- (2023)
Free heme released from hemoglobin contributes to exacerbated inflammation and tissue damage in hemolytic diseases. While a moderate level of free heme does not cause intravascular inflammation by itself, its presence during infection greatly enhance
Externí odkaz:
https://doaj.org/article/caf0e5f9c6324117a28d75b119f708d1
Autor:
Gustavo Monnerat, Micaela L. Alarcón, Luiz R. Vasconcellos, Camila Hochman-Mendez, Guilherme Brasil, Rosana A. Bassani, Oscar Casis, Daniela Malan, Leonardo H. Travassos, Marisa Sepúlveda, Juan Ignacio Burgos, Martin Vila-Petroff, Fabiano F. Dutra, Marcelo T. Bozza, Claudia N. Paiva, Adriana Bastos Carvalho, Adriana Bonomo, Bernd K. Fleischmann, Antonio Carlos Campos de Carvalho, Emiliano Medei
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/a2e0e508ba484f888703530cef72d553
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
Leishmaniasis is an infectious disease caused by protozoans of the genus Leishmania. The macrophage is the resident cell in which the parasite replicates and it is important to identify new compounds that can aid in parasite elimination since the dru
Externí odkaz:
https://doaj.org/article/b12fc921674540bab4f7d6f00c4b557c
Autor:
Gustavo Monnerat, Micaela L. Alarcón, Luiz R. Vasconcellos, Camila Hochman-Mendez, Guilherme Brasil, Rosana A. Bassani, Oscar Casis, Daniela Malan, Leonardo H. Travassos, Marisa Sepúlveda, Juan Ignacio Burgos, Martin Vila-Petroff, Fabiano F. Dutra, Marcelo T. Bozza, Claudia N. Paiva, Adriana Bastos Carvalho, Adriana Bonomo, Bernd K. Fleischmann, Antonio Carlos Campos de Carvalho, Emiliano Medei
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Ventricular arrhythmia is a leading cause of death in patients with diabetes. Here the authors show that inflammasome activation and ILK-1β production in cardiac macrophages cause arrhythmia in diabetic mice, which can be successfully treated using
Externí odkaz:
https://doaj.org/article/dd521bbbf78046d888ba049b54d46e2e
Autor:
Milena B. P. Soares, Renata Gonçalves, Alexandre S. Pyrrho, Deise A. Costa, Claudia N. Paiva, Cerli R. Gattass
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 75, Iss 2, Pp 167-172 (2003)
We have previously demonstrated that inoculation of BALB/c mice with trypomastigotes of CL-14, an avirulent Trypanosoma cruzi clone, prevents the development of parasitemia and mortality after challenge with virulent CL strain. In this report, we inv
Externí odkaz:
https://doaj.org/article/bfc77d573c834150bebfc910c9604f02
Publikováno v:
Journal of Parasitology Research, Vol 2012 (2012)
Macrophage migration inhibitory factor (MIF) is a cytokine that plays a central role in immune and inflammatory responses. In the present paper, we discussed the participation of MIF in the immune response to protozoan parasite infections. As a gener
Externí odkaz:
https://doaj.org/article/25eb38d0ee4b4fec977642eec8a6abb5
Autor:
Hilton A. Mata-Santos, Daniel V. Tausk, Claudia N. Paiva, Marcio Watanabe, Ellen Guimarães, Francisco Cardoso
Short article asking for retraction of the paper by Borba et al. (Jama Network Open, 2020) due to the use of a potentially lethal dose of chloroquine in the clinical trial. As we show, the study attempted to follow the dose recommended by the Chinese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b41444749c39defda6c60a5a9a0528a
Autor:
Elisa Beatriz Prestes, Bénédicte Manoury, Pedro Lagerblad de Oliveira, Andreza Moreira Gama, Caroline Pereira Gomes, Danielle A. S. Rodrigues, Rafael Cardoso Maciel Costa Silva, Claudia N. Paiva, Marcelo T. Bozza, Luis Tan
Publikováno v:
Free Radical Biology and Medicine
Free Radical Biology and Medicine, Elsevier, 2021, 173, pp.104-116. ⟨10.1016/j.freeradbiomed.2021.07.028⟩
Free Radical Biology and Medicine, Elsevier, 2021, 173, pp.104-116. ⟨10.1016/j.freeradbiomed.2021.07.028⟩
Background Chloroquine has been used successfully to treat Malaria, including by chloroquine-resistant Plasmodium sp., indicating that it has effects on disease itself. Since heme has inflammatory effects and contributes to the pathogenesis of hemoly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d2fe3ac7c0215e91b365cbc05ecab3
https://hal.archives-ouvertes.fr/hal-03453897
https://hal.archives-ouvertes.fr/hal-03453897
Publikováno v:
Clinical Reviews in Allergy & Immunology. 58:15-24
Macrophage migration inhibitory factor (MIF) is an inflammatory cytokine that participates in innate and adaptive immune responses. MIF contributes to the resistance against infection agents, but also to the cellular and tissue damage in infectious,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c28b790455240d7623da9f728023e6c1
https://doi.org/10.1007/s12016-019-08726-z
https://doi.org/10.1007/s12016-019-08726-z
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 7, p e1008599 (2020)
PLoS Pathogens, Vol 16, Iss 7, p e1008599 (2020)
Heme oxygenase (HO-1) mediates the enzymatic cleavage of heme, a molecule with proinflammatory and prooxidant properties. HO-1 activity deeply impacts host capacity to tolerate infection through reduction of tissue damage or affecting resistance, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4273a776e03ed49e49adb61fd01e2309
http://europepmc.org/articles/PMC7373268
http://europepmc.org/articles/PMC7373268