Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Claudia Miele"'
Autor:
Antonella Desiderio, Monica Pastorino, Michele Campitelli, Michele Longo, Claudia Miele, Raffaele Napoli, Francesco Beguinot, Gregory Alexander Raciti
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Cardiovascular diseases (CVD) affect over half a billion people worldwide and are the leading cause of global deaths. In particular, due to population aging and worldwide spreading of risk factors, the prevalence of heart failure
Externí odkaz:
https://doaj.org/article/22874d2adca3478a96d405b07b92ac66
Autor:
Michele Longo, Federica Zatterale, Rosa Spinelli, Jamal Naderi, Luca Parrillo, Pasqualina Florese, Cecilia Nigro, Alessia Leone, Augusta Moccia, Antonella Desiderio, Gregory A. Raciti, Claudia Miele, Ulf Smith, Francesco Beguinot
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-24 (2023)
Abstract Background First-degree relatives of type 2 diabetics (FDR) exhibit a high risk of developing type 2 diabetes (T2D) and feature subcutaneous adipocyte hypertrophy, independent of obesity. In FDR, adipose cell abnormalities contribute to earl
Externí odkaz:
https://doaj.org/article/67d0a5fc91c74ab8832d99e8826746b5
Autor:
Serena Cabaro, Ayewa L. Agognon, Cecilia Nigro, Sonia Orso, Immacolata Prevenzano, Alessia Leone, Cristina Morelli, Federica Mormone, Serena Romano, Claudia Miele, Francesco Beguinot, Pietro Formisano, Francesco Oriente
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 11891 (2023)
PREP1 is a homeodomain transcription factor that impairs metabolism and is involved in age-related aortic thickening. In this study, we evaluated the role of PREP1 on endothelial function. Mouse Aortic Endothelial Cells (MAECs) transiently transfecte
Externí odkaz:
https://doaj.org/article/f253ce7e89c544da8372a958509fe42f
Autor:
Alessia Leone, Antonella Nicolò, Immacolata Prevenzano, Federica Zatterale, Michele Longo, Antonella Desiderio, Rosa Spinelli, Michele Campitelli, Domenico Conza, Gregory Alexander Raciti, Francesco Beguinot, Cecilia Nigro, Claudia Miele
Publikováno v:
Cells, Vol 12, Iss 13, p 1741 (2023)
Adipose-derived stem cells (ADSCs) play a crucial role in angiogenesis and repair of damaged tissues. However, in pathological conditions including diabetes, ADSC function is compromised. This work aims at evaluating the effect of Methylglyoxal (MGO)
Externí odkaz:
https://doaj.org/article/ae86b98c3888430b893c0a56643f7c45
Autor:
Marco Milone, Antonella Desiderio, Nunzio Velotti, Michele Manigrasso, Sara Vertaldi, Umberto Bracale, Michele D’Ambra, Giuseppe Servillo, Giuseppe De Simone, Fatima Domenica Elisa De Palma, Giuseppe Perruolo, Gregory Alexander Raciti, Claudia Miele, Francesco Beguinot, Giovanni Domenico De Palma
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract No clear consensus on the need to perform an intracorporeal anastomosis (IA) after laparoscopic right colectomy is currently available. One of the potential benefits of intracorporeal anastomosis may be a reduction in surgical stress. Herein
Externí odkaz:
https://doaj.org/article/4c8ab5a4e9e14868a773269f5bec8b0d
Autor:
Maria Rosaria Ambrosio, Giusy Mosca, Teresa Migliaccio, Domenico Liguoro, Gisella Nele, Fabrizio Schonauer, Francesco D’Andrea, Federica Liotti, Nella Prevete, Rosa Marina Melillo, Carla Reale, Concetta Ambrosino, Claudia Miele, Francesco Beguinot, Vittoria D’Esposito, Pietro Formisano
Publikováno v:
Cancers, Vol 14, Iss 21, p 5421 (2022)
Adiposity and diabetes affect breast cancer (BC) progression. We addressed whether glucose may affect the interaction between mammary adipose tissue-derived mesenchymal stromal/stem cells (MAT-MSCs) and BC cells. Two-dimensional co-cultures and spher
Externí odkaz:
https://doaj.org/article/812e9264e186481cb135ae041314c331
Autor:
Gianluca Bianchini, Cecilia Nigro, Anna Sirico, Rubina Novelli, Immacolata Prevenzano, Claudia Miele, Francesco Beguinot, Andrea Aramini
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 139, Iss , Pp 111613- (2021)
G-protein coupled receptors 40 and 120 (GPR40 and GPR120) are increasingly emerging as potential therapeutic targets for the treatment of altered glucose homeostasis, and their agonists are under evaluation for their glucagon-like peptide-1 (GLP-1)-m
Externí odkaz:
https://doaj.org/article/ff02de5f55984e2eaf598240e9f57907
Autor:
Alessia Leone, Cecilia Nigro, Antonella Nicolò, Immacolata Prevenzano, Pietro Formisano, Francesco Beguinot, Claudia Miele
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
One of the hallmarks of cancer cells is their metabolic reprogramming, which includes the preference for the use of anaerobic glycolysis to produce energy, even in presence of normal oxygen levels. This phenomenon, known as “Warburg effect”, lead
Externí odkaz:
https://doaj.org/article/3117bd5e35df44038a8159231201f332
Autor:
Luca Ulianich, Paola Mirra, Corrado Garbi, Gaetano Calì, Domenico Conza, Antonella Sonia Treglia, Alessandro Miraglia, Dario Punzi, Claudia Miele, Gregory Alexander Raciti, Francesco Beguinot, Eduardo Consiglio, Bruno Di Jeso
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
The endoplasmic reticulum stress and the unfolded protein response are triggered following an imbalance between protein load and protein folding. Until recently, two possible outcomes of the unfolded protein response have been considered: life or dea
Externí odkaz:
https://doaj.org/article/7cd84bf4c0da44c8a574057c161573b8
Autor:
Luca Parrillo, Rosa Spinelli, Mattia Costanzo, Pasqualina Florese, Serena Cabaro, Antonella Desiderio, Immacolata Prevenzano, Gregory Alexander Raciti, Ulf Smith, Claudia Miele, Pietro Formisano, Raffaele Napoli, Francesco Beguinot
Publikováno v:
Cells, Vol 11, Iss 4, p 728 (2022)
Along with insulin resistance and increased risk of type 2 diabetes (T2D), lean first-degree relatives of T2D subjects (FDR) feature impaired adipogenesis in subcutaneous adipose tissue (SAT) and subcutaneous adipocyte hypertrophy well before diabete
Externí odkaz:
https://doaj.org/article/c5fb346355f44d8097e2c7d9804d2b22